A5044499506- Homelessness and Social Issues
- Schizophrenia research and treatment
- Substance Abuse Treatment and Outcomes
- Neurotransmitter Receptor Influence on Behavior
- Food Security and Health in Diverse Populations
- Psychiatric care and mental health services
- COVID-19 and Mental Health
- Suicide and Self-Harm Studies
- Mental Health Treatment and Access
- Housing, Finance, and Neoliberalism
- Digital Mental Health Interventions
- Treatment of Major Depression
- Psychedelics and Drug Studies
- Opioid Use Disorder Treatment
- Bipolar Disorder and Treatment
- Psychosomatic Disorders and Their Treatments
- Neural and Behavioral Psychology Studies
- Migration, Health and Trauma
- Maternal Mental Health During Pregnancy and Postpartum
- Tryptophan and brain disorders
- Genetic Associations and Epidemiology
- Virtual Reality Applications and Impacts
- Health and Medical Studies
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Charité - Universitätsmedizin Berlin
2016-2025
Humboldt-Universität zu Berlin
2011-2025
Freie Universität Berlin
2017-2025
St. Hedwig-Krankenhaus
2011-2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2022
University Psychiatric Hospital
2017
University of Zurich
2017
Ludwig-Maximilians-Universität München
2017
University of British Columbia
2017
Quality and Reliability (Greece)
2013
Background Homelessness continues to be a pressing public health concern in many countries, and mental disorders homeless persons contribute their high rates of morbidity mortality. Many primary studies have estimated prevalence for individuals. We conducted systematic review meta-analysis on the any disorder major psychiatric diagnoses clearly defined populations high-income country. Methods findings systematically searched observational that samples individuals, using Medline, Embase,...
Context: Schizophrenia is the collective term for a heterogeneous group of mental disorders with still obscure biological basis.In particular, specific contribution risk or candidate gene variants to complex schizophrenic phenotype largely unknown.Objective: To prepare ground novel "phenomics" approach, unique schizophrenia patient database was established by GRAS (Göttingen Research Association Schizophrenia), designed allow association genetic information quantifiable phenotypes.Because...
Abstract Background Most studies agree that the Covid-19 pandemic and subsequent lockdown had a negative impact on mental health. On other hand, international have shown psychiatric emergency departments (pED) experienced decrease in presentations admissions. Methods Retrospective chart review of all pED admissions during first wave Germany (Covid-19 period: 3/2/20 to 05/24/20) hospital Berlin compared 1 year earlier (pre-Covid-19 period). Descriptive statistics logistic regression were...
Background While hemispheric specialization of language processing is well established, lateralization emotion still under debate. Several conflicting hypotheses have been proposed, including right hemisphere hypothesis, valence asymmetry hypothesis and region-specific hypothesis. However, experimental evidence for these remains inconclusive, partly because direct comparisons between hemispheres are scarce. Methods The present fMRI study systematically investigated functional during...
Abstract Neuropsychological studies reported decoding deficits of emotional facial expressions in alcohol‐dependent patients, and imaging revealed reduced prefrontal limbic activation during face processing. However, it remains unclear whether this neural is mediated by alcohol‐associated volume reductions interacts with treatment outcome. We combined analyses an aversive face‐cue‐comparison task local gray matter volumes ( GM ) using B iological P arametric M apping 33 detoxified patients...
In recent years, different forms of poverty and their interaction with mental illness have been in the focus research, although implementation action health care policy making so far is scarce. This perspective article offers perspectives its reciprocal association outlines possible future research implications. We will approach topic from various levels: On a micro-level, focusing on absolute precarious housing malnutrition. meso-level, neighborhood-related as factor individuals' illness....
Abstract One of the leading drug addiction theories states that habits and underlying neural process a ventral to dorsal striatal shift are building blocks compulsive drug‐seeking behaviour compulsion is maladaptive persistence responding despite adverse consequences. Here we discuss as defined primarily from perspective animal experimentation falls short clinical phenomena their neurobiological correlates. Thus for human condition, concept should be critically addressed potentially revised.
Clozapine is highly effective for treatment-resistant schizophrenia but underutilized due to patient and clinician-related concerns. Little known about the general level of satisfaction with clozapine determinants thereof. We therefore explored in individuals diagnosed spectrum disorders (SSDs). Cross-sectional data from 480 users were used examine demographic clinical factors, including symptom severity, treatment response, adverse drug reactions (ADRs). Patient was self-rated on a scale 1...
Abstract Clozapine is the most effective antipsychotic for patients with treatment-resistant schizophrenia. However, response highly variable and possible genetic underpinnings of this variability remain unknown. Here, we performed polygenic risk score (PRS) analyses to estimate amount variance in symptom severity among clozapine-treated explained by PRSs (R2) examined association between genotype-predicted CYP1A2, CYP2D6, CYP2C19 enzyme activity. Genome-wide (GWA) were explore loci...
Psychiatric patients are prone to mental health deterioration during the Covid-19 pandemic. Little is known about suicidality in psychiatric This study a retrospective chart review of emergency department (pED) presentations with present or absent (5634 pED attendances, 4110 patients) an academic Berlin, Germany. Poisson regression analysis was performed on effect period (suicidal ideation (SI), suicide plans (SP) attempt (SA)) first (3/2/2020-5/24/2020 "first-wave") and second...