A5004822611- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- Tuberculosis Research and Epidemiology
- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- Immunotherapy and Immune Responses
- Respiratory viral infections research
- SARS-CoV-2 detection and testing
- Pneumonia and Respiratory Infections
- Metabolomics and Mass Spectrometry Studies
- Syphilis Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Diabetes and associated disorders
- Pregnancy and preeclampsia studies
- Dermatologic Treatments and Research
- COVID-19 Clinical Research Studies
- Vaccine Coverage and Hesitancy
- Temporomandibular Joint Disorders
- Advanced biosensing and bioanalysis techniques
- Pneumocystis jirovecii pneumonia detection and treatment
- Biosensors and Analytical Detection
- Hemoglobinopathies and Related Disorders
- Virology and Viral Diseases
- Biomedical and Engineering Education
- Orthodontics and Dentofacial Orthopedics
Institute of Liver and Biliary Sciences
2020-2024
Defence Research and Development Establishment
2024
Manubhai Patel Dental College and Hospital
2023
University of Aberdeen
2021
American Dental Education Association
2020-2021
Czech Academy of Sciences, Institute of Biotechnology
2019-2020
Jamia Hamdard
2020
Indian Institute of Technology Guwahati
2018
MedStar Washington Hospital Center
2012
This study investigates the integration of Artificial Intelligence in contemporary dental practices, focusing on its impact and implementation. A structured survey administered to 150 professionals evaluates awareness, adoption rates perceived benefits artificial intelligence technologies dentistry. Simulated data reveals emerging trends applications, including diagnostic accuracy, treatment planning efficiency patient management optimization. Findings highlight a growing acceptance...
Abstract The recent Coronavirus Disease 2019 (COVID-19) causes an immense health crisis to global public health. COVID-19 is the etiologic agent of a recently arose disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Presently, there no vaccine available against this emerged viral disease. Therefore, it indeed need hour develop effectual and safe decidedly pandemic In current study, we collected SARS-CoV-2 genome which prominent in India human host, further more...
The SARS-CoV-2 Omicron (B.1.1.529) variant emerged in early November 2021 and its rapid spread created fear worldwide. This was attributed to increased infectivity escaping immune mechanisms. spike protein of has more mutations (>30) than any other previous variants declared as the concern (VOC) by WHO. among scientific community huge about this variant, a piece updated information on circulating viral strains is important order better understand epidemiology, virus pathogenicity,...
The recent emergence of COVID-19 has caused an immense global public health crisis. etiological agent is the novel coronavirus SARS-CoV-2. More research in field developing effective vaccines against this emergent viral disease indeed a need hour.The aim study was to identify vaccine candidates that can offer new milestone battle COVID-19.We used reverse vaccinology approach explore SARS-CoV-2 genome among strains prominent India. Epitopes were predicted and then molecular docking simulation...
The purpose of this study was to use cone bar CT investigate the root trench morphology two-hundred mesiobuccal permanent first molars in maxilla.The distobuccal and palatal roots were removed at furcation 250 maxillary molars. then imaged using beam computed tomography on all specimens. specimens analyzed compared one another." This looked into following factors. How Many Canals There Are What Shape Those Take Errors such as lateral canals, apical delta, calcified segments,...
In this protocol, we describe global proteome profiling for the respiratory specimen of COVID-19 patients, patients suspected with COVID-19, and H1N1 patients. details identifying host, viral, or bacterial (Meta-proteome) are provided. Major steps protocol include virus inactivation, protein quantification digestion, desalting peptides, high-resolution mass spectrometry (HRMS)-based analysis, downstream bioinformatics analysis. For complete on use execution profile, please refer to Maras et...
Background: Mycobacterium tuberculosis is a causative agent of tuberculosis. It non-motile, acid-fast, obligatory aerobic bacterium. Finding novel drug targets in has become extremely important as the bacterium evolving into more dangerous multi-drug resistant pathogen. The predominant strains India belong to Central-Asian, East- African Indian, and Beijing clad. For same reason, whole proteomes non-virulent strain (H37Ra), virulent (H37Rv) two clinical strains, Central-Asian clad...
In the current investigation, aqueous two-phase methodology with polyethylene glycol (PEG) 6000/phosphate salt has been used for single-step purification of β-galactosidase from recombinant Pichia pastoris. Optimized parameters 12% (w/w) concentration, 25% polymer 0.6 (mg/ml) protein load and 0.1 M ionic concentration resulted in a maximum 4.7 fold 97% yield. The enzyme kinetic study purified revealed Vm Km 97.087 (U/mg), 0.027(U/mg), 0.07 (U/mg) 0.7 (mM), 11.13 10.73 (mM)...
ChatGPT, an AI chatbot, has the potential to revolutionize field of orthodontics by providing valuable support orthodontists, staff, and patients. By leveraging its natural language processing capabilities, ChatGPT can assist in several ways, including answering patient questions, educational information about orthodontic treatments, offering post-treatment guidance, even supporting staff managing administrative tasks. The implementation practices improve satisfaction, streamline...
Introduction: Parkinson's disease (PD) is the widespread neurodegenerative disorder ranked second in this categories and PD also most common movement disorder.PD affects more than 0.1% of total population older 40 years age.Contemporary, therapies are restricted to only symptomatic relief without dealing with basic etiology such as aggregation αSyn, thus progression continues current therapies.The major objective study was find out putative inhibitors human alfa-synuclein search possible...
Introduction: Hemolysis, elevated liver enzymes and low platelets (HELLP) is a rare (0.5-0.9%) complication of pregnancy mostly seen in the 3rd trimester. Presentation prior to 20 weeks gestation very rare. Here we report case HELLP which was diagnosed at 17 gestation. Case Report-A 40 year old, pregnant woman presented with nausea, vomiting diffuse abdominal pain. Her blood pressure 150/90 mm Hg. She had icterus tenderness. Laboratory investigation revealed hemoglobin 10.9 gm/dL, platelet...
Context: Tuberculosis (TB) is among the top ten causes of mortality, and to control this growing burden disease, it imperative that all TB patients receive same quality care, based on best evidence available. The practices for as enshrined in International Standards Care (ISTC) if adhered can expedite efforts TB. Aims: aim study was evaluate current diagnosis treatment private medical practitioners against benchmark ISTC assess factors associated with adherence ISTC. Subjects Methods: A...
Background: Pneumococcal conjugate vaccine (PCV-13) has been introduced in India a phased manner. In Haryana it was 2017. The adverse events following immunization (AEFI) with PCV real community setting are yet to be detected. Objective: To calculate the incidence and associated factors for various AEFI after pneumococcal vaccination at tertiary centre of Faridabad, Haryana. Methodology: descriptive observational study conducted from April through October 2019 care Each dose PCV-13 given...
Rapid diagnosis and outcome prediction of SARS-CoV-2 infection remains a major challenge. A multi-omic approach was adopted, in the discovery phase, respiratory specimens 20 positive, negative 5 H1N1 positive cases were subjected to global proteomics, metaproteomics metabolomics. We identified MX1 (MX Dynamin like GTPase 1) WARS (Tryptophan--tRNA ligase) as clues viral which validated 200 suspects. MX1>30pg/ml WARS>25ng/ml distinctly segregated virus positives [AUC=94%CI(0.91-0.97)], severe...
Abstract BACKGROUNDProgression of dental caries can result in irreversible pulpal damage. Partial pulpitis, is the initial stage this damage, confined to coronal pulp whilst radicular show little or no sign infection. Preserving with sustained vitality and developing minimally invasive biologically based therapies are key themes within contemporary clinical practice. However, root canal treatment involving complete removal often only option (other than extraction) given patients substantial...
<sec> <title>BACKGROUND</title> The recent emergence of COVID-19 has caused an immense global public health crisis. etiological agent is the novel coronavirus SARS-CoV-2. More research in field developing effective vaccines against this emergent viral disease indeed a need hour. </sec> <title>OBJECTIVE</title> aim study was to identify vaccine candidates that can offer new milestone battle COVID-19. <title>METHODS</title> We used reverse vaccinology approach explore SARS-CoV-2 genome among...