A5019324474- Bee Products Chemical Analysis
- Genomics, phytochemicals, and oxidative stress
- Healthcare and Venom Research
- Insect and Pesticide Research
- Essential Oils and Antimicrobial Activity
- Photodynamic Therapy Research Studies
- Healthcare Regulation
- Toxin Mechanisms and Immunotoxins
- Coffee research and impacts
- MicroRNA in disease regulation
- Bacterial biofilms and quorum sensing
- Biological Research and Disease Studies
- Bacterial Identification and Susceptibility Testing
- Pharmacogenetics and Drug Metabolism
- Algal biology and biofuel production
- Folate and B Vitamins Research
- Nanoplatforms for cancer theranostics
- Cancer Immunotherapy and Biomarkers
- Biosensors and Analytical Detection
- Energy and Environment Impacts
- Phytochemistry Medicinal Plant Applications
- Antimicrobial Resistance in Staphylococcus
Fox Chase Cancer Center
2023-2024
Universidade Estadual Paulista (Unesp)
2015-2022
Colorectal cancer (CRC) is one of most common cancers worldwide, with high rates mortality. Epidemiological findings demonstrate that coffee consumption reduces the risk developing CRC by ~13%. In general, in vivo and vitro antiproliferative, antioxidant proapoptotic effects brewed or major bioavailable compounds. Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates early-stage chemically induced mouse colon carcinogenesis. Male Swiss mice were submitted to a...
The aim of this study was to evaluate the antimicrobial susceptibility profile 85 Staphylococcus epidermidis and 84 haemolyticus strains isolated from blood cultures oxacillin, vancomycin, tigecycline, linezolid, daptomycin, quinupristin/dalfopristin over a period 12 years. S. inpatients, attended at teaching hospital, were analyzed for presence mecA gene by SCCmec typing. minimum inhibitory concentration (MIC) values quinupristin/dalfopristin, vancomycin determined. Isolates exhibiting MICs...
The effects of propolis and phenolic compounds (caffeic acid - Caf; dihydrocinnamic Cin; p-coumaric Cou) in the same quantity found our sample were investigated on human laryngeal epidermoid carcinoma (HEp-2) cells.Cell viability, apoptosis/necrosis cell cycle arrest, P53 CASPASE-3 gene expression, generation reactive oxygen species (ROS) ability to induce doxorubicin (DOX) efflux using a P-glycoprotein (P-gp) inhibitor (verapamil) assayed.Propolis exerted cytotoxic effect HEp-2 cells,...
Abstract Colorectal cancer is the third most diagnosed worldwide and linked to dietary/lifestyle factors. Arthrospira ( Spirulina) platensis (AP) contains bioactive compounds with beneficial effects in vivo / vitro . We evaluated of AP feeding against 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis. Male Sprague Dawley rats were given subcutaneous injections DMH (4 × 40 mg/kg body weight) (G1–G3) or vehicle (G4–G5) twice a week (weeks 3–4). During weeks 1–4, animals fed diet...
The current standard of care for colon cancer surveillance relies heavily on white light endoscopy (WLE). However, dysplastic lesions that are not visible to the naked eye often missed when conventional WLE equipment is used. Although dye-based chromoendoscopy shows promise, dyes cannot delineate tumor tissues from surrounding healthy accurately. goal present study was screen various phthalocyanine (PC) dye-loaded micelles their ability improve direct visualization under following...
Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) characterized by persistent mucosal inflammation extending throughout the colon. Due to compromised intestinal surface integrity and prolonged use of medication, individuals with UC often develop folate deficiency, requiring folic acid (FA) supplementation. Prior findings from this group indicate that FA supplementation, at clinically relevant levels, promotes UC-associated dysplasia. Supplementation resulted in...
Introdução: O câncer colorretal (CCR) é uma neoplasia que acomete pessoas com vida sedentária e alimentação rica em gordura, carne vermelha pobre fibras estão relacionadas incidência mortalidade para esse câncer. A Spirulina platensis (Sp) possui capacidade antioxidante anti-inflamatória podendo ser um alimento potencial preventivo contra o CCR. Objetivo: Este trabalho tem como objetivo avaliar efeito da Sp (1 2% na dieta) nas etapas iniciação promoção carcinogênese de cólon induzida pela...