A5102770429- Reproductive Biology and Fertility
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Nutritional Studies and Diet
- Birth, Development, and Health
- Cardiac Arrest and Resuscitation
- Obesity, Physical Activity, Diet
- Folate and B Vitamins Research
- Trauma and Emergency Care Studies
- Prenatal Substance Exposure Effects
- Traumatic Brain Injury and Neurovascular Disturbances
- Sperm and Testicular Function
- Vitamin D Research Studies
- Gestational Diabetes Research and Management
- Traumatic Brain Injury Research
- Maternal and Perinatal Health Interventions
- Reproductive Health and Technologies
- Antioxidant Activity and Oxidative Stress
- Emergency and Acute Care Studies
- Pregnancy and preeclampsia studies
- Obstructive Sleep Apnea Research
- Reproductive System and Pregnancy
- Stress Responses and Cortisol
- Prostate Cancer Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
Alexander T. Augusta Military Medical Center
2019-2024
The University of Texas Health Science Center at Houston
2024
United States Department of Veterans Affairs
2024
National Institute on Aging
2019-2024
National Institutes of Health
2024
Shepherd Center
2023
Western Carolina University
2022
Johns Hopkins University
2016-2022
Johns Hopkins Medicine
2017-2022
Triangle
2020
Background. Inactivated polio vaccine (IPV) is necessary for global eradication because oral can rarely cause poliomyelitis as it mutates and may fail to provide adequate immunity in immunocompromised populations. However, IPV unaffordable many developing countries. Intradermal shows promise a means decrease the effective dose cost of IPV, but prior studies, all using 20% standard used intramuscular resulted inferior antibody titers. Methods. We randomly assigned 231 adults with...
We examined associations of physical intimate partner violence (PIPV) with selected mental health disorders using a nationally representative sample emergency department (ED) discharges corresponding to men and women (18-64 years) from the 2010 Nationwide Emergency Department Sample.PIPV was determined International Classification Disease, 9th Revision, Clinical Modification (ICD-9-CM) external cause injury code E967.3 (battering by spouse or partner). ICD-9-CM clinical classification...
Abstract The plasma proteome can mediate associations between periodontal disease (Pd) and brain white matter integrity (WMI). We screened 5089 UK Biobank participants aged 40–70 years for poor oral health problems (POHP). examined the association POHP WMI (fractional anisotropy (FA), mean diffusivity (MD), Intracellular Volume Fraction (ICVF), Isotropic (ISOVF) Orientation Diffusion (OD)), decomposing total effect through of 1463 proteins into pure mediation, interaction, neither, while...
Objectives To determine if there are changes in the central apnea index (CAI) when pediatric patients undergo adenotonsillectomy for obstructive sleep (OSA). Study Design Case series with chart review. Setting Two tertiary children’s hospitals. Subjects and Methods Children between 1 16 years of age who underwent OSA had both preoperative postoperative full‐night polysomnography (PSG) CAI greater than on PSG were eligible inclusion. Central was defined as absence inspiratory effort chest...
Visceral adipose tissue (VAT) is a key contributor to chronic inflammation in obesity. The 12/15-lipoxygenase pathway (ALOX) present (AT) and leads inflammatory cascades that are causal for the onset of insulin resistance rodent models pathophysiology ALOX 12/15 human AT unknown. We characterized different depots obese humans with or without type 2 diabetes (T2D). This study includes cross-sectional cohort 46 morbidly (body mass index >39 kg/m2) nondiabetic (n = 25) T2D 21) subjects. was...
Increased expression of CD169 on monocytes has been reported in HIV-1-infected humans. Using rhesus macaque models HIV infection, we sought to investigate whether simian immunodeficiency virus (SIV) infection upregulates monocytes/macrophages. We also determine CD8 T cells and plasma viral load directly impact the during SIV infection. longitudinally assessed monocyte course by flow cytometry, examined macrophages immunohistochemistry spleen lymph nodes uninfected infected macaques. was...
Although herpes simplex virus (HSV)-1 and HSV-2 may co-exist interact, some epidemiologic features including geographical distribution, secular trends, route of transmission, established risk factors distinguish these HSV sub-types. With recent data indicating a link between genital either strain, re-evaluation for HSV-1/HSV-2 infection co-infection is needed.We used the 1999-2004 National Health Nutrition Examination Study (NHANES) logistic regression modeling to identify socio-demographic...
Objective Rheumatoid arthritis, a condition of unknown etiology, has been associated with considerable costs to society. The purpose this study is determine whether selected reproductive history characteristics are postmenopausal rheumatoid arthritis diagnosis. Methods Secondary analyses were performed using cross-sectional data from the Third National Health and Nutrition Examination Survey. Of 1,892 eligible participants, 182 fulfilled criteria for based on self-report 1987 American...
Recent studies have shown that postoperative antibiotics in nonperforated appendicitis do not reduce infectious complications; however, there is no consensus on patients with complicated appendicitis. The aim of this study to determine whether antibiotic administration prevents intra-abdominal abscess formation. We conducted a retrospective chart review all undergoing appendectomy from 2007 2012 at our institution. Patients (perforated, gangrenous, or periappendiceal abscess) were identified...
Abstract The role of dairy foods and related nutrients in cardiometabolic health aetiology is poorly understood. We investigated longitudinal associations between the metabolic syndrome (MetS) its components with key product exposures. used prospective data from a bi-racial cohort urban adults (30–64 years at baseline ( n 1371)), Healthy Aging Neighborhoods Diversity across Life Span (HANDLS), Baltimore City, MD (2004–2013). average two 24-h dietary recalls measured 4–10 d apart was computed...
Abstract Background Elevated levels of inflammatory biomarkers are consistently associated with chronic conditions, for which periodontitis and sleep established risk factors. We examined the relationships between periodontitis, hours white blood cell (WBC) markers among a nationally representative sample US adults. Methods Cross‐sectional study using existing demographic, examination, laboratory questionnaire data on 11,813 participants (5,814 men 5,999 women, mean age ± SE; range: 52.74...
Abstract Background We compared outcomes of therapeutic plasma exchange (TPE) vs intravenous immunoglobulin (IVIG) among hospitalized patients diagnosed with Guillain‐Barré syndrome (GBS). Methods In a retrospective cohort study 6642 records (2637 TPE and 4005 IVIG) from the 2002–2014 Nationwide Inpatient Sample, treatment type was examined as predictor length stay, total charges, in‐hospital death, regression modeling using risk adjustment propensity scoring to control for confounders....
<i>Background:</i> Cancer-specific mortality is projected to be only 1% in 15 years approximately 75% of patients with screen-detected localized prostate cancer (LPC). Nearly 94% choose treatment even though damages health-related quality life. No data are available regarding what survival benefit expected from treatment. <i>Objectives:</i> A self-administered mailed survey was sent 184 men newly diagnosed LPC query about versus observation. <i>Results:</i> More than 90% had at least a high...