Jie Guo

ORCID: 0000-0002-5003-9785
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Research Areas
  • Vagus Nerve Stimulation Research
  • Endometrial and Cervical Cancer Treatments
  • Gastroesophageal reflux and treatments
  • Gastrointestinal motility and disorders
  • Sarcoma Diagnosis and Treatment
  • Acupuncture Treatment Research Studies
  • Management of metastatic bone disease
  • Gut microbiota and health
  • Anesthesia and Neurotoxicity Research
  • Hepatitis B Virus Studies
  • Garlic and Onion Studies
  • Ultrasound and Hyperthermia Applications
  • Urinary Bladder and Prostate Research
  • Dysphagia Assessment and Management
  • Oral microbiology and periodontitis research
  • Esophageal Cancer Research and Treatment
  • Heart Rate Variability and Autonomic Control
  • Gallbladder and Bile Duct Disorders
  • Eosinophilic Esophagitis
  • 3D Printing in Biomedical Research
  • Hepatitis C virus research
  • Pediatric Pain Management Techniques
  • Neurological Disorders and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Traditional Chinese Medicine Analysis

China Pharmaceutical University
2024

Xianyang Normal University
2022

Second Affiliated Hospital of Jilin University
2017-2020

Wuhan No.1 Hospital
2017-2019

Johns Hopkins University
2019

First Affiliated Hospital of Bengbu Medical College
2019

Guangzhou Development Zone Hospital
2005

The purpose of this study was to determine the effects and mechanisms vagal nerve stimulation (VNS) additive electroacupuncture (EA) on colonic inflammation in a rodent model IBD. Chronic rats induced by intrarectal TNBS (2,4,6-trinitrobenzenesulfonic acid). were then treated with sham ES (electrical stimulation), VNS, or VNS + EA for 3 wk. Inflammatory responses assessed disease activity index (DAI), macroscopic scores histological tissues, plasma levels TNFα, IL-1β, IL-6, myeloperoxidase...

10.1152/ajpgi.00254.2016 article EN AJP Gastrointestinal and Liver Physiology 2017-05-26

Abstract Background Vagal nerve stimulation (VNS) was reported to have a therapeutic potential for inflammatory bowel disease (IBD). This study designed determine effects and mechanisms of SNS on colonic inflammation in rodent models IBD compare the difference among SNS, VNS, plus VNS. Methods Intestinal rats induced by intrarectal administration TNBS (2,4,6‐Trinitrobenzenesulfonic acid) first day. Five days after TNBS, were treated with sham‐VNS, Sham‐SNS, + VNS 10 days. In another...

10.1111/nmo.13676 article EN publisher-specific-oa Neurogastroenterology & Motility 2019-07-21

Abstract Background Acupuncture has been widely accepted for treatments of many diseases. This study was performed to determine effects and mechanisms electroacupuncture (EA) by chronically implanted electrodes at acupoint ST36 on colonic inflammation induced TNBS in rats. Methods After intrarectal administration TNBS, the rats were treated with sham‐EA, EA1/EA2 (two sets parameters) 3 weeks. Disease activity index (DAI), macroscopic microscopic lesions, plasma levels TNF‐α, IL‐1β IL‐6...

10.1111/nmo.13615 article EN Neurogastroenterology & Motility 2019-05-22

High-resolution manometry (HRM) is used to assess esophageal motility diseases. Abnormalities in a number of HRM parameters have been reported patients with dysphagia. However, it unclear whether some abnormal are predictive The aim this retrospective study was investigate the roles predicting incomplete bolus clearance (IBC) dysphagia using high-resolution impedance manometry.A total 644 wet swallows were reviewed and analyzed 63 symptoms or reflux who underwent clinical test. IBC defined...

10.1097/mcg.0000000000000949 article EN Journal of Clinical Gastroenterology 2017-10-31

The aim of this study was to research the antiapoptotic effect astragaloside, principal component Astragalus membranaceus (Fisch) Bge, in human gingiva cells induced by lipopolysaccharide (LPS).According treatment, were divided into five groups, including (1) control group without drug treatment; (2) imitating group, treated with LPS (10 μg·mL-1 ) alone; (3) low and 50 μmol·L -1 astragaloside; (4) medium 100 (5) high 150 astragaloside. Cell proliferation apoptosis investigated using MTT...

10.1002/jcb.28286 article EN Journal of Cellular Biochemistry 2019-04-18

Objective To examine the dosimetric advantages of three-dimensional (3D) computed tomography (CT)-guided interstitial brachytherapy (BT) for target volume and surrounding normal tissue in patients with locally advanced cervical cancer, to provide a simple effective clinical treatment approach. Methods A total 52 who had poor tumor response external beam radiotherapy (EBRT) residual greater than 5 cm at time BT were included. The treated by 3D CT-guided using hybrid applicator...

10.3760/cma.j.issn.1004-4221.2017.05.015 article EN Zhonghua fangshe zhongliuxue zazhi 2017-05-15

Objective To investigate the dosimetric difference between inverse planning simulated annealing (IPSA) and manual optimized plan for isodose line in interstitial brachytherapy locally advanced cervical cancer to provide a better optimization method clinical application. Methods A total of 104 patients with were enrolled this study. They received pelvic external beam radiotherapy five fractions. Both IPSA used optimize dose each fraction. Dose volume parameters two plans compared...

10.3760/cma.j.issn.1004-4221.2017.11.010 article EN Zhonghua fangshe zhongliuxue zazhi 2017-11-15

Objective To discuss the dosimetric advantage of computed tomography-guided interstitial brachytherapy compared with conventional intracavitary for locally advanced cervical cancer, offering a more advantageous clinical treatment approach. Methods Twenty-eight cancer patients bulky tumors (tumor size>5 cm) after external beam radiotherapy received brachytherapy. Dosimetric outcomes current study, including total dose (external radiotherapy+ brachytherapy) D90 HR-CTV and D2cc bladder,...

10.3760/cma.j.issn.1004-4221.2018.06.011 article EN Zhonghua fangshe zhongliuxue zazhi 2018-06-15

Objective: To investigate the effects of preoperative percutaneous transhepatic biliary drainage on surgical treatment type Ⅲ and Ⅳ hilar cholangiocarcinoma. Methods: Clinical data 72 patients with cholangiocarcinoma Bismuth-Corlette treated at Department General Surgery,First Affiliated Hospital Bengbu Medical College from January 2010 to December 2017 were analyzed retrospectively.Patients divided into two groups based whether PTBD was performed:a drained group an undrained group.In...

10.3760/cma.j.issn.0529-5815.2019.04.009 article EN PubMed 2019-04-01
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