A5000262736- Cardiovascular Function and Risk Factors
- Cancer Research and Treatments
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Peripheral Neuropathies and Disorders
- Neuroblastoma Research and Treatments
- Microscopic Colitis
- Computational Drug Discovery Methods
- Hepatocellular Carcinoma Treatment and Prognosis
- Probiotics and Fermented Foods
- Essential Oils and Antimicrobial Activity
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Synthesis and biological activity
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Parkinson's Disease and Spinal Disorders
- Acute Myocardial Infarction Research
- Abdominal Trauma and Injuries
- Spondyloarthritis Studies and Treatments
- Foreign Body Medical Cases
- Gastrointestinal Bleeding Diagnosis and Treatment
- Melanoma and MAPK Pathways
- Microbial Metabolism and Applications
- Long-Term Effects of COVID-19
Victor Babeș University of Medicine and Pharmacy Timișoara
2008-2025
West University of Timişoara
2018
County Hospital
2008
Abstract Backgrounds Acotiamide is a novel acetylcholinesterase inhibitor for treatment of postprandial distress syndrome ( PDS ) symptoms functional dyspepsia FD ). This European phase 3 open‐label safety trial has been conducted to evaluate the long‐term acotiamide and explore efficacy on using validated LPDS , quality life SF ‐36 ‐ NDI work productivity WPAI . Methods patients (defined by ROME III criteria) aged ≥18 years with active without predominant overlapping epigastric pain related...
Skin injuries, and especially wounds of chronic nature, can cause a major negative impact on the quality life. New efficient alternatives are needed for wound healing therapy herbal products being investigated due to high content natural compounds with promising activity. For this purpose, we three Artemisia species, absinthium L. (AAb), dracunculus (ADr) annua (AAn). Ethanolic extracts, containing different polyphenolic compounds, elicited strong antioxidant activities in DPPH assay,...
Most studies analyzing data from patients who experienced at least one episode of acute COVID-19 infection have attributed the cascade immediate and late complications to disruption inflammatory system neutrophil activity in particular. Among various functions neutrophils is release pro-inflammatory mediators, including interleukin-6 (IL-6). Oxidative stress induced by mediators secreted leads vascular endothelial dysfunction. Neutrophil counts neutrophil-to-lymphocyte ratio (NLR) are...
Cancer remains a leading cause of death worldwide and, even though several advances have been made in terms specific treatment, the late-stage detection and associated side effects conventional drugs sustain search for better treatment alternatives. Probiotics are live microorganisms that proven to possess numerous health benefits human hosts, including anticancer effects. In present study, vitro effect association two probiotic strains (PBT), Lactobacillus sporogenes Clostridium butyricum,...
Despite the notable advancements witnessed in past decade medical and health research domain, cancer remains a prominent global cause of mortality. Moreover, conventional treatments employed to combat this disease have been found considerably compromise quality life experienced by patients due its severe side effects. Recent vitro studies revealed encouraging findings on potential beneficial effects probiotics as adjuvants anticancer therapy, even possible agents for prevention treatment...
The goal of this study was to assess whether subtle changes in myocardial work indices may predict left ventricular (LV) remodeling and major cardiac events (MACEs) patients with a first ST-elevation acute infarction (STEMI) preserved LVEF after successful revascularization PCI. Methods. Consecutive STEMI sinus rhythm an LV ejection fraction ≥ 50% following PCI were recruited. Conventional two-dimensional speckle tracking echocardiography (2D-STE) conducted within 36 h the 3 months later....
The components of metabolic syndrome (MS) are risk factors for developing both cardiovascular disease (CVD) and non-alcoholic fatty liver (NAFLD). Strain (SI) strain‑rate imaging (SRI) able to recognize early changes in cardiac function. Vibration-controlled transient elastography (VCTE) controlled attenuation parameter (CAP) detect quantify fibrosis steatosis. We aimed assess whether there is any correlation between steatosis left ventricular (LV) dysfunction MS patients.A total 150 adults...
Mebendazole and flubendazole are antihelmintic drugs that have re-entered the research spotlight due to their exhibited anticancer effects, thus making them strong candidates as repurposed drugs. However, these benzimidazole derivatives exhibit poor solubility in water various organic solvents, which limits bioavailability. With aim of obtaining an improved drug increased biological effect, mebendazole were complexed with 2-hydroxypropyl-β-cyclodextrin (HPBCD). The binary 1:1 conjugates...
Broncho-esophageal fistula (BEF) is a severe yet relatively rare connection between the bronchus and esophagus usually caused by esophageal pulmonary malignancies. We present case report of 49-year-old man diagnosed with terminal lung carcinoma who developed BEF. The thoracic computed tomography scan detected mass in left bronchi that partially covers disrupts bronchial contour certain regions extends to wall. After thoroughly evaluating alternative treatment approaches, we opt for stenting...
This case report describes an uncommon overlap syndrome between ankylosing spondylitis (AS) and amyotrophic lateral sclerosis (ALS). Initially, the patient was diagnosed with AS, for which he received various specific treatments, including TNF-α inhibitors. After five years of treatment inhibitor etanercept, referred a full neurological assessment after reported balance disturbances, postural instability, muscle weakness, other symptoms that indicated presence disorder. thorough...
The current study proposes the in vitro and silico anticancer evaluation of clove (
Background and Aims: Real-world assessments of efficacy safety advanced therapies used for inflammatory bowel disease (IBD) patients are limited. We aimed to report safety, treatment persistence new molecules (infliximab, adalimumab, vedolizumab, tofacitinib, ustekinumab) in a retrospective multicentric national Romanian analysis.
 Methods: conducted nationwide, observational study. Data were collected retrospectively from electronic paper files. Patients who started on one the five...
Important achievements have been obtained in paediatric oncology the last period of time domain diagnosis and therapy. To obtain a good evolution malign process on child, it is very important to diagnose an early stage. We reported prospective study over 5 years with 30 children abdominal tumours which had proven be malignant. As initial diagnostic method power triplex ultrasound was principal investigation this proves its importance for screenings paediatry. Colour Doppler contrast...
Probiotic strains such as Lactobacillus spp. are already known for their beneficial effect on human health and new research supports role in colon cancer prevention treatment. The current study reports the of different concentrations Lacticaseibacillus rhamnosus (LGG, 106–109 CFU/mL), alone or association with 5-fluorouracil (5-FU, 10 μM), tested against normal HaCaT cells, HT-29 colorectal adenocarcinoma HCT-116 carcinoma cell lines. underlying cytotoxic was further investigated. LGG...
Aim: The most frequent risk factors for urinary tract infection in elderly, witch can be diagnosed using an abdominal ultrasound exam, are: nephrolithiasis, renal cysts, nephroptosis, tumors causing exterior obstruction on the and benign prostate hyperplasia or cancer men. aim of this study is to establish UTI elderly residents community ultrasound.
Subcapsular and intraparenchymatous hepatic hematomas (HH) raise special management problems due to parenchymatous associated lesions. Despite intense rapid liver regeneration, this process is affected by the presence of bile. Therefore nonoperative determines a weak slow healing. The drainage fluid (biliohepatic collection), surgical hepatostomy or percutaneous drainage, promotes optimal cure. Laparotomy with solutioning HH method important morbidity mortality, but transhepatic US guided...
Objective: The diagnosis of pancreatic tumors affections is facilitated by abdominal echography, completed when necessary, TC and MRI.
Aim: Urinary tract infection (UTI) is a common problem in the elderly. Diagnosis, prevention, and treatment can be complex because clinical manifestations atypical host defenses diminish with age. The aim of this study to establish role renal ultrasound diagnosing chronic pielonephritis elderly patients.
Ultrasound guided puncture biopsy represents a useful instrument in the diagnostic approach of tumoral masses, having as main advantages minimally invasive character, possibility performing procedure ambulatory or daily admittance, histopathological exam from extracted material.
Background: Hepatic tumors affections have most often an atypical debut, and the minimal biological modifications are shown only by imagistic exam: abdominal echography completed TC, MRI simple or contrast.
Objective: The aim of the study was evaluation characteristics and advantages home blood pressure monitoring (HBPM), compared with office (BP) measurement to establish its utility in primary care offices. Design method: From 2314 annual examinations (1st. visit), detected 255 subjects (11.01%) newly diagnosed HT. On second visit, involving 200 these cases grade I II hypertension, BP hypertension 182 (91%) patients normal 18 (9%). Home confirmed 128 (84.76%) sustained 23 (15.24%) white-coat...