A5057489926- Liver Disease Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Gallbladder and Bile Duct Disorders
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Cardiovascular Function and Risk Factors
- Animal Virus Infections Studies
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Infrared Thermography in Medicine
- Cardiovascular Disease and Adiposity
- Pediatric Hepatobiliary Diseases and Treatments
- Ultrasound Imaging and Elastography
- Diet, Metabolism, and Disease
- Cardiovascular Health and Disease Prevention
- Colorectal Cancer Screening and Detection
- Diabetes Management and Research
- Systemic Sclerosis and Related Diseases
- Diabetes and associated disorders
- Leprosy Research and Treatment
- Congenital gastrointestinal and neural anomalies
Victor Babeș University of Medicine and Pharmacy Timișoara
2016-2025
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara
2022
Hospital Braga
2012
The performance of percutaneous echo-guided biopsy in the hepatic tumoral diagnosis is limited (90% sensitivity) by several factors, among which tumor characteristics (type, size, and location) play an important role. Contrast enhanced ultrasound guided (CEUS-PLB) a new developed technique aimed at increasing accuracy biopsies. objective our study was to evaluate feasibility CEUS as guiding method performing liver (PLB).One hundred seventy one patients with tumors referred department for LB...
To evaluate the performance of 2D shear-wave elastography from General Electric (2D-SWE.GE) for noninvasiveassessment liver fibrosis and to identify stiffness (LS) cut-off values predicting different stages fibrosisusing Transient Elastography (TE) as reference method.We included 331 consecutive subjectswith or without chronic hepatopathies in whom LS was evaluated same session by means 2 elastographic techniques:TE 2D-SWE.GE. Reliable measurements were defined TE median value 10 with a...
Type 2 diabetes mellitus (T2DM), obesity, hyperlipidemia, and hypertension are considered risk factors for developing non-alcoholic fatty liver disease (NAFLD). This study aims to assess steatosis fibrosis severity in a cohort of T2DM patients, using vibration controlled transient elastography (VCTE) attenuation parameter (CAP).We performed prospective which, each patient, we aimed 10 valid CAP stiffness measurements (LSM). To discriminate between stages, used the following VCTE cut-offs: F...
Liver stiffness (LS) measurement by Transient Elastography (TE) has been widely accepted as a tool for fibrosis assessment. The aim of this study was to assess LS dynamics in group patients with HCV liver cirrhosis after interferon free treatment (IFT).This two-center clinical trial included 225 compensated (all genotype 1b), who received IFT 12 weeks. All were evaluated means TE at the beginning and end (EOT), subgroup (170 patients) also weeks EOT; all them had sustained viral response...
Abstract Background Since nonalcoholic fatty liver disease (NAFLD) has become the leading cause of in Western world, clinicians need reliable noninvasive tools for identification NAFLD-associated fibrosis. Limited evidence on performance novel shear wave elastography technique Elast-PQ (EPQ) NAFLD is available. Method In this prospective, European multinational study we assessed diagnostic accuracy EPQ using vibration-controlled transient (VCTE) as a reference standard. Results Among 353...
Reliable liver stiffness measurements (RLSM) using Transient Elastography (TE) with the standard M probe are difficult to obtain in overweight (BMI≥25kg/m2) and obese (BMI>30kg/m2) patients. The aim of our paper was assess feasibility TE daily practice both XL probes.We studied retrospectively 3235 patients chronic disease assessed by first (standard – transducer frequency 3.5 MHz), if were unreliable, (transducer 2.5 MHz). defined as median 10 valid a success rate ≥ 60% an interquartile...
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic diseases worldwide. The aim our study was to evaluate a population diabetic patients regarding severity steatosis and fibrosis.The included 392 type 2 prospectively randomized, evaluated in same session by transabdominal ultrasound assess elastography fibrosis (Transient Elastography - TE, FibroScan, EchoSens). Steatosis graded using semi-quantitative scale (S0-no steatosis; S1-mild S2-moderate S3-severe steatosis)....
Aim: The study compared the usefulness of 2D-SWE and attenuation measurements obtained using Aplio i800 from Canon together with Transient Elastography (TE) Controlled Attenuation Parameter (CAP) as reference method.Material methods: We included 112 consecutive adults reliable LS measurements, 44 healthy subjects 68 chronic hepatopathies in whom liver stiffness (LS) steatosis were evaluated same session employing two elastography techniques: implemented on FibroScan® 530 Compact system Two...
Elastography is a useful noninvasive tool for the assessment of renal transplant recipients. 2D-shear wave elastography (SWE) PLUS and viscosity plane-wave ultrasound (Vi PLUS) have emerged as novel techniques that promise to offer improved stiffness measures due processing algorithms. Methods: We performed cross-sectional study 50 kidney transplanted patients (16 women, 34 men; mean age 47.5 ± 12.5; estimated glomerular filtration rate (eGFR) by Chronic Kidney Disease Epidemiology...
Non-invasive methods to assess the severity of chronic liver diseases have become more and popular. The aim our study was evaluate correlation four Shear Waves Elastographic in a cohort patients with mixed etiologies compare their performances for fibrosis evaluation. A prospective conducted on 127 consecutive etiologies. LS measurements were performed all subjects, one session, during same day, by means 4 elastographic methods: Transient Elastography (TE), Virtual Touch Quantification...
Background: Whether endoscopic ultrasound (EUS) contrast-enhanced fine-needle aspiration (CH-EUS-FNA) determines superior results in comparison to standard EUS-FNA tissue acquisition of pancreatic masses remains unclear. The aim this study was compare these two techniques on a series patients with solid lesions. Methods: 362 underwent (2008–2019), after the propensity score matching groups were compared; 103 treated CH-EUS-FNA (group 1) and 2). primary outcome diagnostic accuracy. Secondary...
Abstract Purpose Liver stiffness measurement (LSM) using vibration-controlled transient elastography (VCTE) or two-dimensional shear wave (2D-SWE) is recommended to assess the risk of liver fibrosis and advanced chronic disease. Even though both techniques measure stiffness, their numerical results often diverge. Confounders reliability criteria for 2D-SWE have not been systematically investigated. Materials Methods We prospectively recruited participants with paired LSM by VCTE novel...
This study evaluated ElastQ, a two-dimensional shear wave elastography (2D-SWE) technique, for the non-invasive assessment of liver fibrosis risk using stiffness measurement (LSM). The aim was to determine its diagnostic accuracy and establish LSM cutoffs clinical stratification.A prospective multicenter conducted, employing vibration-controlled transient (VCTE) as reference standard. statistical analysis utilized Pearson correlations Lin concordance correlation coefficients, areas under...
The constitutive elements of the metabolic syndrome (MetS) are linked with both non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease. Controlled attenuation parameter (CAP), vibration controlled transient elastography (VCTE), able to detect quantify NAFLD, while conventional two-dimensional speckle tracking echocardiography (2D-STE) is capable identify subclinical changes in cardiac function. We wanted evaluate whether there any correspondence between left ventricular (LV)...
The components of metabolic syndrome (MS) are risk factors for developing both cardiovascular disease (CVD) and non-alcoholic fatty liver (NAFLD). Strain (SI) strain‑rate imaging (SRI) able to recognize early changes in cardiac function. Vibration-controlled transient elastography (VCTE) controlled attenuation parameter (CAP) detect quantify fibrosis steatosis. We aimed assess whether there is any correlation between steatosis left ventricular (LV) dysfunction MS patients.A total 150 adults...
This is a retrospective single-center study that included 87 subjects. All subjects had chronic hepatitis B or HBV cirrhosis and underwent nucleos(t)ide analogs (NUC) treatment for more than one year. The aimed to evaluate the dynamic changes in liver stiffness (LS) measured by transient elastography (TE) during median interval of 64 months. Patients were assessed prior starting therapy followed up annually. Liver measurements (LSM) performed annually, ten valid LSMs obtained each session....
Background and Objectives: Diabetes mellitus (DM) is connected to both cardiovascular disease non-alcoholic fatty liver (NAFLD), an important component of metabolic syndrome (MetS). NAFLD can be detected quantified using the vibration controlled transient elastography (VCTE) attenuation parameter (CAP), whereas traditional two-dimensional speckle tracking echocardiography (2D-STE) reveal subclinical abnormalities in heart function. We sought see if there was a link between left cardiac...
Primary lactose intolerance (PLI) is characterized by the inability to digest lactose. Homozygotes for lactase gene polymorphisms (CC or GG) are considered be genetically predisposed PLI. Still, symptoms may only present later in life. The evidence supporting a link between PLI, dairy intake, and quality of life (QoL) limited children.This study investigates LCT suggestive influence genetic predisposition PLI on intake QoL Romanian children.We recruited consecutive children evaluated our...