A5037519397- Dialysis and Renal Disease Management
- Ultrasound Imaging and Elastography
- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
- Ultrasound and Hyperthermia Applications
- Parathyroid Disorders and Treatments
- Renal and Vascular Pathologies
- Cardiovascular Health and Disease Prevention
- Renal Diseases and Glomerulopathies
- Liver Disease Diagnosis and Treatment
- Nephrotoxicity and Medicinal Plants
- Systemic Sclerosis and Related Diseases
- Electrical and Bioimpedance Tomography
- Potassium and Related Disorders
- Central Venous Catheters and Hemodialysis
- Cardiovascular Function and Risk Factors
- Thyroid Cancer Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Biomedical Research and Pathophysiology
- Hepatitis C virus research
- Diabetes Treatment and Management
- Muscle and Compartmental Disorders
- Vascular Procedures and Complications
- Urinary Tract Infections Management
- Vitamin K Research Studies
Victor Babeș University of Medicine and Pharmacy Timișoara
2016-2025
Clinical Emergency Hospital Bucharest
2007-2023
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara
2022-2023
West University of Timişoara
2006-2018
Pediatric Nephrology of Alabama
2013-2015
Başkent University
2006
Dammam Central Hospital
2006
Shiraz University of Medical Sciences
2006
University Clinical Centre
2006
Camera de Comerț Industrie și Agricultură Timișoara
2005
Epidemiological data of renal disease are available from large national biopsy registries Central and Western European countries; in contrast, detailed epidemiological Eastern countries missing. This report is the first review histological data, over a period 10 years (1995-2004), covering population 6 million inhabitants two distinct regions an East country - Romania.635 eco-guided kidney biopsies Moldova (North-Eastern Romania, 8 counties, 4 754 048 inhabitants) Banat (Western 3 1 454 747...
Chronic kidney disease (CKD) is a prevalent cause of morbidity and mortality worldwide. A hallmark CKD progression renal fibrosis characterized by excessive accumulation extracellular matrix (ECM) proteins. In this study, we aimed to investigate the correlation urinary proteome classifier CKD273 individual peptides with degree fibrosis. total, 42 biopsies urine samples were examined. The percentage per total tissue area was assessed in Masson trichrome stained tissues. analysed capillary...
to assess the inter-operator reproducibility of kidney shear wave speed, evaluated by means Acoustic Radiation Force Impulse (ARFI) elastography, and factors which influence it.Our prospective pilot study included 107 subjects with or without pathology in speed was ARFI elastography. Intraclass correlation coefficient (ICC) used elastography reproducibility.A strong agreement obtained between measurements two operators: ICC = 0.71 (right kidney) 0.69 (left kidney). Smaller ICCs were "healthy...
The aim of the study was to establish relationship between estimated glomerular filtration rate (GFR) and kidney shear wave speed values assessed by acoustic radiation force impulse (ARFI) elastography.Our included 104 patients with or without chronic disease in which evaluated ARFI elastography correlated GFR. Five measurements were performed parenchyma each kidney. A median value expressed as meters per second calculated.Five valid elastographic obtained right all left 97.1% patients. mean...
The aim of this study was to evidence trends and changes in mortality, comorbid conditions, prognosis, causes death after 5 years continuous evolution hemodialysis (HD) patients Romania.We included two cohorts stable HD (901 from 2012 1396 2017). Both were followed up for 1 year. 5-year survivors the cohort identified 2017 their data assessed.The older, with longer time on dialysis, higher serum creatinine urea levels, required ultrafiltration volume per dialysis. They also had lower...
Background/Objectives: Urinary tract infections (UTI) represent a global problem with implications for mortality and morbidity. Published data present different bacterial incidences antibiotic resistance. The objective of our study is to evaluate the bacteria distribution in positive urine cultures mixed adult population differences resistance in- outpatients. Methods: We analyzed 1186 2021 from Emergency County Hospital “Pius Brinzeu” Timisoara, Romania. evaluated stratified by outpatients...
Background End stage renal disease (ESRD) patients on replacement therapy (RRT) with diabetes mellitus (DM) have a higher mortality rate and an increase prevalence of vitamin D deficiency compared to those without DM. It is still debated if risk factor or prognostic marker for in these patients. This study investigated the its impact all-cause HD Methods Our prospective non-interventional cohort included 600 hemodialysis (HD) (median aged 56, interquartile range (19) years, 332 (55.3%)...
Introduction Acute kidney injury (AKI) increases the risk of death in acute ischemic stroke (AIS) patients. Intravenous thrombolytic therapy (iv. rt-PA) seems to be most effective treatment for AIS The effects AKI on iv. rt-PA treated cases is less studied. Our paper addresses this issue. Methods 45 consecutive patients with (median age = 64 years; 29 male) and 59 sex matched controls not eligible have been enrolled our study. Subjects were followed-up until hospital release or follow up...
A renal biopsy represents the gold standard in diagnosis, prognosis, and management of patients with glomerulonephritis. So far, non-invasive elastographic techniques have not confirmed their utility replacing a biopsy; however, new improved software from Hologic Supersonic Mach 30 is promising method for assessing tissue's stiffness viscosity. We investigated whether this elastography technique could reveal tissue fibrosis chronic glomerulonephritis.Two-dimensional-shear wave (SWE) PLUS...
<b><i>Background:</i></b> End-stage renal disease patients can be considered as ‘cardiovascular time bombs' due to their tremendous cardiovascular risk. Our study has determined the impact of 3 months exercise training during dialysis on some risk factors (arterial stiffness, body composition and physical performance) in a chronic hemodialyzed population. <b><i>Methods:</i></b> The group (n = 19) control 16) hemodialysis from Timisoara,...
Patients with end-stage renal disease (ESRD) have an increased risk of all-cause mortality. The prognostic value the new cardiac biomarkers, cardiotrophin 1 (CT-1) and galectin 3 (GAL-3), has not yet been defined in hemodialysis (HD) patients. aim this study was to determine use these novel biomarkers for predicting mortality HD Plasma GAL-3 CT-1 concentrations were determined (at baseline) 88 patients followed 22.2 ± 4.7 months. During follow-up period, 21 (23.9%) deaths recorded. According...
Chronic kidney disease is a rising cause of morbidity and mortality in developed countries, including end-stage renal (ESRD). The prevalence thyroid comorbidities persons with chronic documented higher than normal population. study aims to investigate the morphological functional disorders patients disease, replacement therapy (hemodialysis).A cross-sectional was performed on 123 consecutive stage 5, hemodialysis during period one month (May 2019-June 2020). All were enrolled for maintenance...
Studies published so far using ultrasound-based elastography in the kidneys, lack to prove a clear relationship between kidney shear wave speed (KSWS) and renal disease progression. Taking into account that is highly vascularized organ, present study aims find KSWS vascular factors (blood pressure [BP], arterial stiffness). Our included 38 diabetic patients (mean age 56.52 ± 16.12 years, 19 female, male). KSWS, an indicator of stiffness, was measured point Shear Wave Elastography (pSWE;...
Abstract This study aimed to analyze the utility of bidimensional shear-wave elastography for renal assessment and in prediction chronic kidney disease (CKD). The included 92 subjects: 50 healthy volunteers 42 patients with different degrees CKD (mean age, 57.5 ± 13.4; 50% were female), excluding those undergoing replacement therapies, obstructive pathology, or lithiasis. We performed velocity (KSWV) determinations midportion parenchyma each kidney. median values expressed meters per second....
Introduction Kidney dysfunction is prevalent in oncology patients and has an impact on their treatment quality of life. The aim our study was to analyze the prevalence CKD a large cohort several types cancer East European Region. Material methods We conducted observational retrospective 5831 consecutive, biopsy-diagnosed between January 2019 –December 2020 largest hospital outpatient clinic Western Romania. 4342 subjects were included statistical analysis. Results discussion From 24 types,...
Elastography is a useful noninvasive tool for the assessment of renal transplant recipients. 2D-shear wave elastography (SWE) PLUS and viscosity plane-wave ultrasound (Vi PLUS) have emerged as novel techniques that promise to offer improved stiffness measures due processing algorithms. Methods: We performed cross-sectional study 50 kidney transplanted patients (16 women, 34 men; mean age 47.5 ± 12.5; estimated glomerular filtration rate (eGFR) by Chronic Kidney Disease Epidemiology...