The aim of this study was to evidence trends and changes in mortality, comorbid conditions, prognosis, causes death after 5 years continuous evolution hemodialysis (HD) patients Romania.We included two cohorts stable HD (901 from 2012 1396 2017). Both were followed up for 1 year. 5-year survivors the cohort identified 2017 their data assessed.The older, with longer time on dialysis, higher serum creatinine urea levels, required ultrafiltration volume per dialysis. They also had lower...

Introduction: Contrast-induced nephropathy (CIN) has emerged as a prevalent and serious complication associated with the administration of iodinated contrast media during diagnostic therapeutic procedures. Given rising global prevalence chronic kidney disease(CKD,) it is crucial to gain deeper understanding risks linked exposure. Therefore, aim this study, conducted at Vascular Surgery Clinic in tertiary hospital Eastern Europe (Timisoara, Romania), assess incidence CIN identify its risk...

Background/Objectives: Urinary tract infections (UTI) represent a global problem with implications for mortality and morbidity. Published data present different bacterial incidences antibiotic resistance. The objective of our study is to evaluate the bacteria distribution in positive urine cultures mixed adult population differences resistance in- outpatients. Methods: We analyzed 1186 2021 from Emergency County Hospital “Pius Brinzeu” Timisoara, Romania. evaluated stratified by outpatients...

Neonatal sepsis (NS) remains a significant cause of morbidity and mortality in newborns, particularly preterm low-birthweight infants. It has been shown previously that interleukin-6 (IL-6) can predict sepsis, its non-invasive determination be performed quickly, leading to the diagnosis appropriate treatment for each case. Elevated IL-6 levels have associated with early late-onset NS, showing potential as an indicator infection before onset clinical symptoms. IL-6, conjunction other...

In developed countries, heart disease is the primary cause of maternal mortality during pregnancy. Arterial stiffness, an independent risk factor for atherosclerosis and a predictor cardiovascular complications, can be assessed using augmentation index (AIx) pulse wave velocity (PWV). this prospective study, we aimed to evaluate diverse hemodynamic parameters arterial stiffness in pregnant women before after participating structured, personalized exercise training program.

Introduction Kidney dysfunction is prevalent in oncology patients and has an impact on their treatment quality of life. The aim our study was to analyze the prevalence CKD a large cohort several types cancer East European Region. Material methods We conducted observational retrospective 5831 consecutive, biopsy-diagnosed between January 2019 –December 2020 largest hospital outpatient clinic Western Romania. 4342 subjects were included statistical analysis. Results discussion From 24 types,...

Background: Acute kidney disease (AKD) is a known risk factor for increased mortality and evolution towards chronic (CKD) in adults. The data regarding children are scarce. purpose of our study to explore the AKD impact following an acute injury (AKI) episode on new-onset CKD. Methods: We retrospectively evaluated 736 with ages between 2 18 years old AKI admitted tertiary care hospital from west Romania over 9 period. Results: incidence was 17%. Patients that developed were older, higher...

End-stage kidney disease patients (ESKD) receiving hemodialysis (HD) are at a greater risk of hepatitis virus (HV) infections due to the invasive nature procedures, frequent hospital stays and surgeries, as well immune deficiency status ESKD.This study was reassess prevalence in HD population Romania after 5 years oral DAAs therapy assess impact on patients' outcomes two cohorts (2015 2019).We compared ESKD treated with 10 centers from historical regions 2015 (n = 1401, Mean age 59.7 ± 12.92...

Chronic kidney disease patients treated by hemodialysis present a high cardio-vascular morbidity and mortality. There is an imperative need for novel biomarkers in identifying to offer possible therapeutically intervention these patients. We performed prospective observational cohort study on 77 the period October 2021 – 2023. measured serum plasma levels of Interleukin 1-Beta, Galectin 3, human suppression tumorigenicity factor 2, bone morphogenetic protein 2 fibroblastic growth...

The increase in bacterial resistance is currently a global burden for the health care system. In order to evaluate rates of several bacteria from most encountered cultures clinical practice, we performed retrospective analysis all positive year 2021 tertiary hospital Romania. Our captured 3299 cultures. median age patients was 62 years (IQR: 41-71 old) with slight predominance among females (53.1%). Overall, common were urocultures, wound secretion and blood cultures, identified

Background: Changing the term/concept of non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction associated (MAFLD) may broaden pathological definition that can include chronic renal involvement, and, possibly, changes kidney disease's (CKD's) epidemiological association with disease, because CKD is disorders and almost all patients present some form an atherogenic dyslipidemia. Our study explores relationship between MAFLD using Transient Elastography (TE) a Controlled Attenuated...

Abstract Left ventricular (LV) structure and function anomalies are frequent during the CKD continuum associated with increased risk of mortality. Cross section longitudinal ultrasound data available for advanced transition to ESKD. Less information is about LV changes stable, long-term hemodialysis (HD) treatment. All stable HD patients from 9 centers (1034 patients, 671 males, age 58.71 ± 12.94 years) have been enrolled in January 2015. The cohort was followed-up 4 years, kidney...

Chronic kidney disease patients treated by hemodialysis present a high cardiovascular morbidity and mortality. There is an imperative need for novel biomarkers identifying these to offer possible therapeutically interventions. We performed prospective observational cohort study on 77 in the period of October 2021–October 2023. measured serum plasma levels interleukin 1-beta, galectin 3, human suppression tumorigenicity factor 2, bone morphogenetic protein 2 fibroblastic growth 23 at...

Background: Acute kidney disease (AKD) is a known risk factor for increased mortality and evolution towards chronic (CKD) in adults. The data regarding AKD children are scarce. purpose of our study was to explore the factors developing based on exposures susceptibilities with AKI doubled by biological parameters from first day identified AKI. In addition, we followed trajectory following an acute injury (AKI) episode during hospital admission after discharge special considerations...

The most recent research conducted for the International Federation of Gynecology and Obstetrics indicates that, depending on stage cervical cancer (CC), several therapies can provide similar overall survival progression-free rates. To determine hematologic toxicities during concurrent chemotherapy cancer, we evaluated these two (cisplatin or carboplatin). Hematologic markers have been studied using statistical models descriptive statistics. Artificial intelligence were built treatment data...

Background/Objectives: Urinary tract infections represent a global problem with implications on mortality and morbidity. Published data present different bacterial incidence antibiotics resistances. With this study, we aimed to evaluate bacteria distribution antibiotic resistance in tertiary care hospital from the Western part of Romania. Methods: evaluated all positive urine culture year 2021 Emergency County Hospital “Pius Brinzeu” Timisoara, We 1264 cultures identified following bacteria:...

Background/Objectives: Magnesium plays a crucial role in immune function, influencing immunoglobulin synthesis, antibody-dependent cytolysis, and other processes. In renal transplant patients, magnesium deficiency is primarily induced by calcineurin inhibitor treatment, through the reduction of transporter proteins tubules, leading to loss. Methods: To assess correlation between serum levels long-term outcomes graft recipients, we conducted retrospective study on 87 patients who have had for...

Background and Objectives: Pelvic floor dysfunction sexual health issues are common postpartum due to weakened pelvic muscles, significantly impacting women's quality of life (QoL). muscle training (PFMT) is a widely used approach address these issues. This study aimed compare the effectiveness two rehabilitation methods-vibrating vaginal cones (VCG) PFMT exercises (CG)-in improving strength, reducing dyspareunia, enhancing function in women. Materials Methods: 1-year retrospective...

Liver biopsy is the gold standard method for staging liver fibrosis, but it an invasive procedure that associated with some complications. There are also non-invasive techniques assessing such as elastography and biological tests, these can fail in detection or generate false measurements depending on subject’s condition. This study aimed to determine whether fibrosis be evaluated using contrast-enhanced ultrasonography arrival time parametric imaging ultrasound machine’s image software,...

Abstract Background and Aims Neoplasia is considered a risk factor for the development of CKD, many reasons: aggressive repeated therapeutic interventions, malnutrition, hyperuricemia disease per se. Taking into account improved cancer survival due to novel possibility patients with CKD reach advanced stages increasing. The information about still scarce. This paper tends fill gap by analyzing relation between in large database from western Romania. Method 5831 (3365 female, average age 62.6...

Abstract BACKGROUND AND AIMS Vascular calcifications have been recognized as frequent findings in patients with end-stage renal disease (ESRD) and intricate mechanisms, including chronic kidney disease—mineral bone disorders (CKD-MBD), inflammation advanced atherosclerosis. The pathogenesis of arteriovenous fistula (AVF) is not fully understood, since it involves many other factors related to haemodialysis (HD) such haemodynamic variables or vessel wall shear stress. current study aims...