Non-alcoholic fatty liver disease (NAFLD) is the most common chronic worldwide. This study aimed to evaluate performance of four ultrasound-based techniques for non-invasive multiparametric (MPUS) assessment fibrosis (LF), steatosis (HS), and inflammation in patients with NAFLD. We included 215 consecutive adult NAFLD (mean age: 54.9 ± 11.7; 54.5% were male), whom LF, HS, viscosity evaluated same session using new embedded on Aixplorer MACH 30 system: ShearWave Elastography (2D-SWE.PLUS),...

Background: Sarcopenia is now recognized more and as a biomarker with poor outcomes in cirrhotic patients. Aims: The purpose of this study was to investigate the prevalence sarcopenia patients liver cirrhosis prospectively association between different complications its impact on survival. Material Methods: This prospective included admitted our department from 2018 2020. assessed according EWGSOP2 criteria, incorporating low Handgrip strength (<27 kg for men <16 women)...

To evaluate the performance of 2D shear-wave elastography from General Electric (2D-SWE.GE) for noninvasiveassessment liver fibrosis and to identify stiffness (LS) cut-off values predicting different stages fibrosisusing Transient Elastography (TE) as reference method.We included 331 consecutive subjectswith or without chronic hepatopathies in whom LS was evaluated same session by means 2 elastographic techniques:TE 2D-SWE.GE. Reliable measurements were defined TE median value 10 with a...

Type 2 diabetes mellitus (T2DM), obesity, hyperlipidemia, and hypertension are considered risk factors for developing non-alcoholic fatty liver disease (NAFLD). This study aims to assess steatosis fibrosis severity in a cohort of T2DM patients, using vibration controlled transient elastography (VCTE) attenuation parameter (CAP).We performed prospective which, each patient, we aimed 10 valid CAP stiffness measurements (LSM). To discriminate between stages, used the following VCTE cut-offs: F...

Liver stiffness (LS) measurement by Transient Elastography (TE) has been widely accepted as a tool for fibrosis assessment. The aim of this study was to assess LS dynamics in group patients with HCV liver cirrhosis after interferon free treatment (IFT).This two-center clinical trial included 225 compensated (all genotype 1b), who received IFT 12 weeks. All were evaluated means TE at the beginning and end (EOT), subgroup (170 patients) also weeks EOT; all them had sustained viral response...

Malnutrition and sarcopenia are common complications of liver cirrhosis. This study compares the performance different nutritional assessment techniques in detecting malnourished patients. Data from 156 patients with cirrhosis were collected. We assessed status these according to: Subjective Global Assessment (SGA); Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT), skinfold thickness (TSF), mid-upper arm circumference (MUAC), muscle (MUMC), handgrip strength (HGS), body mass index...

The aim of this study was to assess the dynamics epicardiac adipose tissue (EAT) thickness and total volume as well that systolic diastolic dysfunction in a group patients with type 2 diabetes (T2D) after initiation sodium glucose co-transporter (SGLT 2) inhibitors therapy.This prospective, observational included 53 T2D who received SGLT-2 for 24 weeks. In all patients, echocardiographic screening EAT, non-contrast computed tomography scans were performed, both before weeks inhibition....

Nonalcoholic Fatty Liver Disease (NAFLD) is increasing in frequency daily practice and evaluation of liver steatosis, fibrosis inflammation severity are essential for prognosis assessment. The aim was to evaluate the usefulnessof a new steatosis quantification system - Ultrasound-Guided Attenuation Parameter (UGAP) from General Electric Healthcare, using Controlled (CAP) as reference method.179 consecutive subjects, whom assessed same session UGAP, implemented on LOGIQ E10 (GE Healthcare),...

The management of Helicobacter pylori (H. pylori) infection raises important challenges, still being the most common chronic worldwide in all age groups. In high-prevalence regions, paediatric patients need a specific focus, as acquisition takes place childhood. objective this study was to analyze endoscopic and histopathologic changes gastric mucosa H. infected children.A retrospective performed on consecutive patients, ranging from 0 18 years age, who underwent an upper gastrointestinal...

Lille score at Day 7 (LM7) helps to predict the outcome of patients with severe alcoholic hepatitis (sAH) undergoing corticotherapy. Several scores such as Maddrey’s discriminant function (MDF), MELD, ABIC, and GAHS are used for a 28-day mortality prognosis. Our study aimed evaluate if assessment 4 days (LM4) is useful response corticosteroids utility severity admission predicting prognosis liver cirrhosis (LC) (sAH). A retrospective was performed, all consecutive AH MDF > 32 without...

Acute upper gastrointestinal bleeding (UGIB) is a typical medical emergency, with an incidence of 84 to 160 cases per 100,000 individuals and mortality rate approximately 10%. This study aimed identify all UGIB hospitalized in tertiary gastroenterology department, possible predictive factors involved rebleeding mortality, potential associations between different elements the severity bleeding, differences digestive hemorrhage due nonvariceal variceal bleeding. was observational,...

Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic diseases worldwide. The aim our study was to evaluate a population diabetic patients regarding severity steatosis and fibrosis.The included 392 type 2 prospectively randomized, evaluated in same session by transabdominal ultrasound assess elastography fibrosis (Transient Elastography - TE, FibroScan, EchoSens). Steatosis graded using semi-quantitative scale (S0-no steatosis; S1-mild S2-moderate S3-severe steatosis)....

Aim: To evaluate the feasibility of two elastographic methods, point Shear Wave Elastography (pSWE) and dimensional (2D-SWE), integrated in same ultrasound machine, for liver fibrosis (LF) assessment, using Transient (TE) as reference method.Material methods: We included study 115 subjects which LF was evaluated session by TE (FibroScan, EchoSens), pSWE 2D-SWE (Samsung-Medison RS85). Reliable stiffness (LS) measurements were defined: median value 10 with interquartile range (IQR/M)≤30%,while...

Aim: The study compared the usefulness of 2D-SWE and attenuation measurements obtained using Aplio i800 from Canon together with Transient Elastography (TE) Controlled Attenuation Parameter (CAP) as reference method.Material methods: We included 112 consecutive adults reliable LS measurements, 44 healthy subjects 68 chronic hepatopathies in whom liver stiffness (LS) steatosis were evaluated same session employing two elastography techniques: implemented on FibroScan® 530 Compact system Two...

Non-invasive methods to assess the severity of chronic liver diseases have become more and popular. The aim our study was evaluate correlation four Shear Waves Elastographic in a cohort patients with mixed etiologies compare their performances for fibrosis evaluation. A prospective conducted on 127 consecutive etiologies. LS measurements were performed all subjects, one session, during same day, by means 4 elastographic methods: Transient Elastography (TE), Virtual Touch Quantification...

The study aimed to establish the benefits of using spleen stiffness values measured by two elastography techniques as noninvasive markers for predicting varices needing treatment and comparing their performances. A prospective was performed, including 107 subjects with compensated liver cirrhosis, who underwent upper digestive endoscopy, well measurements means techniques: pSWE (point shear wave Virtual Touch Quantification-Siemens Acuson S2000) 2D-SWE (2D-shear elastography-LOGIQ E9,...

End-stage kidney disease patients (ESKD) receiving hemodialysis (HD) are at a greater risk of hepatitis virus (HV) infections due to the invasive nature procedures, frequent hospital stays and surgeries, as well immune deficiency status ESKD.This study was reassess prevalence in HD population Romania after 5 years oral DAAs therapy assess impact on patients' outcomes two cohorts (2015 2019).We compared ESKD treated with 10 centers from historical regions 2015 (n = 1401, Mean age 59.7 ± 12.92...

Background: Changing the term/concept of non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction associated (MAFLD) may broaden pathological definition that can include chronic renal involvement, and, possibly, changes kidney disease's (CKD's) epidemiological association with disease, because CKD is disorders and almost all patients present some form an atherogenic dyslipidemia. Our study explores relationship between MAFLD using Transient Elastography (TE) a Controlled Attenuated...

To evaluate the range of liver stiffness (LS) cut-off values for predicting different stages fibrosis (LF) 2D-SWE-GE implemented on three systems from General Electric Healthcare (LOGIQ E9, LOGIQ S8, P9).We performed a comparative study evaluating performance P9) LF using Transient Elastography (TE) as reference method. All patients (with or without chronic hepatopathies) were evaluated by TE, 331 included in E9 study, 179 S8 and 234 P9 study. Reliable measurements (LSM) defined TE median...

Background: Multiparametric ultrasound (MPUS) is a concept whereby the examiner encouraged to use latest features of an machine. The aim this study was reanalyze inconclusive focal liver lesions (FLLs) that had been analyzed via contrast enhanced (CEUS) using MPUS approach with help tree-based decision classifier. Materials and methods: We retrospectively FLLs were upon CEUS examination in our department, focusing attention on samples taken over period two years (2017−2018). reanalysis...