A5100748546- Cardiac Ischemia and Reperfusion
- Anesthesia and Neurotoxicity Research
- Acupuncture Treatment Research Studies
- Ophthalmology and Eye Disorders
- Liver Disease and Transplantation
- Medical Research and Treatments
- Anesthesia and Pain Management
- Mechanical Circulatory Support Devices
- Acute Ischemic Stroke Management
- Respiratory viral infections research
- Neonatal and fetal brain pathology
- Cancer Research and Treatments
- Obstructive Sleep Apnea Research
- Traditional Chinese Medicine Studies
- Boron Compounds in Chemistry
- Facial Trauma and Fracture Management
- Anesthesia and Sedative Agents
- Glaucoma and retinal disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Nitric Oxide and Endothelin Effects
- Microbial infections and disease research
- Neurological Disease Mechanisms and Treatments
- Spinal Cord Injury Research
- Cardiac Arrest and Resuscitation
- Bone and Dental Protein Studies
Nanjing Medical University
2020
Zunyi Medical University
2020
Affiliated Hospital of Southwest Medical University
2018
Shanghai Jiao Tong University
2018
Shanghai Children's Medical Center
2012-2018
West China Hospital of Sichuan University
2017
Sichuan University
2017
Tianjin Hospital
2017
Shanxi Medical University
2015
Mudanjiang Medical University
2015
Ischemic post‑conditioning (IPO) and diazoxide (DPO) has been proven to reduce myocardial ischemia reperfusion injury (MIRI); however, the mechanisms of IPO/DPO are still not clear. The present study aimed investigate whether mitochondrial ATP‑sensitive potassium channels (mitoKATP) activated by IPO/DPO, which may further activate hypoxia inducible factor 1/hypoxic response element (HIF‑1/HRE) pathway mitigate MIRI. Using a Langendorff perfusion device, healthy male (250‑300 g) Sprague...
The purpose of this study was to investigate the possible protective effect N-acetylserotonin (NAS) against acute hepatic ischemia-reperfusion (I/R) injury in mice. Adult male mice were randomly divided into three groups: sham, I/R, and I/R + NAS. model generated by clamping artery, portal vein, common bile duct with a microvascular bulldog clamp for 30 min, then removing allowing reperfusion 6 h. Morphologic changes hepatocyte apoptosis evaluated hematoxylin-eosin (HE) terminal...
The relationship between plaque characteristics and their predictive value for perioperative cerebral blood flow (CBF) are unknown.To investigate the carotid CBF utilizing MRI.Prospective.In all, 131 patients with moderate-to-severe stenosis referred endarterectomy (CEA).3T, black-blood T1 - T2 -weighted, 3D time-of-flight, simultaneous noncontrast angiography intraplaque hemorrhage.The relative (rCBF = CBFindex-hemisphere /CBFcontralateral-hemisphere ) difference ratio (DRCBF [CBFpost-CEA...
The authors aim to investigate protective effects of fasciotomy against ischemia reperfusion injury skeletal muscle in rabbit and compare the treatment prereperfusion + postreperfusion muscle. 24 healthy male Japanese white rabbits were randomly divided into 3 groups, 4 hours' was established these through surgery. Six performed group A; postfasciotomy B; prefasciotomy C. Result showed that could protect injury, reduced MDA (malondialdehyde) expression, MPO (myeloperoxidase) apoptosis...
Objective To observe the effectiveness of OPN and it’s competive antagonist GRGDSP in treating subarachnoid hemorrhage rats, study relationship osteopontin (OPN) vascular endothelial growth factor (VEGF), brain derived neurotrophic (BDNF) after (SAH) revealing mechanism pathogenesis SAH. Methods The rats were divided into five different experimental groups: such as Control (6), Sham SAH+ vehicle(12), (12), OPN+ (12). OPN, or vehicle was timely injected left ventricle induced SAH. The...
Objective To evaluate the clinical efficacy and application value of FilmArray Respiratory Panel (FilmArray RP) for Mycoplasma pneumoniae (MP) detection. Methods Methodological evaluation. A total 360 nasopharyngeal swabs or sputum samples were collected from hospitalized children with community acquired pneumonia in Shanghai Children′s Medical Center, Jiao Tong University School Medicine (SCMC) November 2016 to May 2017. Among them, there 197 males 163 females. There 185 cases 0-2...
Objective To evaluate the role of mitochondrial KATP (mito-KATP) channel in pinacidil postconditioning-induced reduction myocardial ischemia-reperfusion (I/R) injury rats. Methods SPF healthy male Sprague-Dawley rats, aged 16-20 weeks, weighing 250-300 g, were anesthetized with pentobarbital.Their hearts excised and perfused a Langendorff apparatus K-H solution saturated 95% O2-5% CO2 at 36.5-37.5 ℃.Thirty-two Langendorff-perfused divided into 4 groups (n=8 each) using random number...