A5068522074- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Pancreatic and Hepatic Oncology Research
- Electrospun Nanofibers in Biomedical Applications
- Medical Research and Treatments
- Medicinal Plant Pharmacodynamics Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Mechanisms and Therapy
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Pancreatitis Pathology and Treatment
- Adipose Tissue and Metabolism
- Acute Myocardial Infarction Research
- Cancer, Lipids, and Metabolism
- Osteoarthritis Treatment and Mechanisms
- MicroRNA in disease regulation
- Skin Protection and Aging
- Lipid metabolism and disorders
- Healthcare and Venom Research
- Dermatologic Treatments and Research
- Aortic aneurysm repair treatments
- Vitamin D Research Studies
Soochow University
2010-2025
First Affiliated Hospital of Soochow University
2010-2025
First Affiliated Hospital of Bengbu Medical College
2025
Tianjin Agricultural University
2024
Hunan University of Technology
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2021
Chongqing Medical University
2021
Xian Central Hospital
2013-2018
People's Hospital of Bishan District
2013
Nanjing Children's Hospital
2013
Introduction: Laennec’s capsule serves as a critical anatomical landmark in liver resection. Despite its potential, lack of large-scale prospective studies limits the widespread use Laennec approach for minimally invasive hepatectomy. This multicenter cohort study aimed to compare outcomes traditional and approaches hepatectomy across multiple centers China. Methods: A total 445 patients from 11 were included, with 339 undergoing 106 receiving approach. Intraoperative parameters such...
The treatment outcomes of traditional patches for chronic soft tissue defects (CSTDs) are unsatisfactory in clinical, owing to the lack intrinsic bioactivities orchestrate intricate regenerative process. To tackle this deficiency, nature-derived microneedles (NMs) composed silk methacrylate and snail mucus developed study. resultant NMs have excellent mechanical strength biological adhesiveness, ensuring suture-free but reliable fixation on implanted site. enhance bioactivities,...
Background Previous studies have shown that metabolic dysfunction associated fatty liver disease (MAFLD) is with thyroid hormones (THs), immunity, and inflammation status, but few involved autoimmunity. This study aimed to evaluate the role of THs, autoantibodies, inflammatory biomarkers in MAFLD, its cofactors, other possible determinants. Materials Methods In study, a total 424 Chinese patients were selected categorized as non-MAFLD MAFLD. Serum hormone, autoantibody high-sensitive...
Intrahepatic cholangiocarcinoma (ICC) is a malignancy with dismal prognosis, thus the discovery of promising diagnostic markers and treatment targets still required. In this study, 1,852 differentially expressed genes (DEGs) were identified in GSE45001 dataset for weighted gene co-expression network analysis (WGCNA), turquoise module was confirmed as key module. Next, subnetworks 1,009 analyzed by MCODE, MCC, BottleNeck algorithms nine overlapping (CAT, APOA1, APOC2, HSD17B4, EHHADH, APOA2,...
Abstract Polyvinyl alcohol (PVA) is well-known for its excellent mechanical properties and eco-friendliness in food packaging. Recently, PVA has gained significant attention research due to potential as antibacterial substrates. However, because of high hydrophilicity, practical application pure film been limited by low water resistance rapid bacterial growth humid conditions. Diverse effective strategies have developed decrease hydrophilicity endow films with properties. This review...
BACKGROUND:miR-181a is a small non-coding RNA known to be dysregulated in osteoarthritis (OA), but the role of miR-181a human OA remains unclear. The aim this study was identify its function and molecular target chondrocytes during pathogenesis. MATERIAL AND METHODS:The assessed by gain-of-function studies chondrocytes. Potential targets were predicted using series bioinformatics intersection analysis, then confirmed luciferase reporter assay. Gene expression quantified quantitative reverse...
Patients with hepatic fibrosis (HF) have a high risk of developing liver cirrhosis and hepatocellular carcinoma, there is an urgent need for preventive strategies to block this process. Previous studies found that disordered inflammation oxidative damage play important roles in HF progression, suggesting two attractive therapeutic targets. Herein, new kind bioinspired microcapsules core-shell structure generated using microfluidics. Polydopamine nanoparticles (PDANPs), synthetic analogue...
Glutathione peroxidase 2 (GPX2) is a selenium-dependent enzyme and protects cells against oxidative damage. Recently, GPX2 has been identified as candidate gene for backfat feed efficiency in pigs. However, it unclear whether regulates the development of porcine preadipocytes skeletal muscle cells. In this study, adenoviral transfer was used to overexpress GPX2. Our findings suggest that overexpression inhibited proliferation preadipocytes. And process accompanied by reduction p-p38....
In the PANDA III trial, novel poly-lactide-co-glycolide polymer-based BuMA sirolimus-eluting stent (SES) was non-inferior to polylactide Excel SES for primary endpoint of one-year target lesion failure (TLF), with a lower incidence thrombosis. We sought investigate whether effectiveness profile SES, more rapid drug elution and polymer absorption kinetics, would persist at two years.A total 2,348 patients (mean age, 61.2±10.6 years; 24.3% diabetics; 31.2% acute myocardial infarction within...
The aim of the study was to investigate correlation between levels 25-hydroxyvitamin D3, vitamin B12 and C endothelial function patients with coronary heart disease (CHD). Forty CHD diagnosed in Shanghai Tenth People's Hospital from May 2016 April 2017 were selected as observation group. A total 45 healthy individuals control participants included 54 males 31 females. General information collected. Peripheral serum biochemical indicators, C, homocysteine (Hcy), nitric oxide (NO) NOS (eNOS)...
Implantation of early-generation metallic drug-eluting stents (DES) in patients with acute myocardial infarction (AMI) is associated poor vessel wall healing. Use biodegradable polymer (BP) DES might improve safety outcomes; however, the impact varying drug elution and absorption kinetics BP-DES on clinical outcomes AMI population unknown.This subgroup analysis randomized PANDA III trial included 732 (366 each group) presenting recent (<1 month) AMI. Primary endpoint was 1-year target lesion...
Abstract Objectives The aim of the present report was to compare 2‐year safety outcomes two biodegradable polymer (BP) sirolimus‐eluting stents (SESs) with different drug eluting and absorption kinetics in a subgroup complex patients lesions. Background previously published PANDA III study showed BuMA BP SES, faster elution absorption, non‐inferior Excel SES target lesion failure (TLF). Methods In trial, who fulfilled one or more following criteria were included: Small vessel disease...
Metabolic reprogramming is a feature of tumour cells and essential to support their rapid proliferation. The glycolytic activity liver cancer significantly higher than that normal cells, the rapidly proliferating are powered by aerobic glycolysis. Lipid metabolism enables meet needs for highly proliferative growth an important driving force development hepatocellular carcinoma (HCC).To explore influence different metabolic subtypes HCC analyse significance in guiding prognosis treatment...