- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Lung Cancer Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Cardiovascular Effects of Exercise
- Ion channel regulation and function
- Lung Cancer Treatments and Mutations
- Neuroscience and Neural Engineering
- Cardiac Valve Diseases and Treatments
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Hip and Femur Fractures
- Cardiac Structural Anomalies and Repair
- Bone fractures and treatments
- Homelessness and Social Issues
- Restraint-Related Deaths
- Orthopedic Surgery and Rehabilitation
- Autopsy Techniques and Outcomes
- Foreign Body Medical Cases
- Management of metastatic bone disease
- Vasculitis and related conditions
- Medical Malpractice and Liability Issues
- Muscle and Compartmental Disorders
University of Utah
2022-2025
Commonwealth Medical College
2022
Community Medical Center
2020-2022
San Francisco General Hospital
2021
University of California, San Francisco
2017-2021
Queen Alexandra Hospital
2014-2018
Institute of Medical Sciences
2018
Northwestern University
2010-2015
University of Wollongong
2015
Nizam's Institute of Medical Sciences
2013
Although the development of abnormal myocardial mechanics represents a key step during transition from hypertension to overt heart failure (HF), underlying ultrastructural and cellular basis remains unclear. We therefore investigated how changes in transverse (T)-tubule organization resulting altered intracellular Ca(2+) cycling large cell populations underlie model chronic hypertension. Hearts spontaneously hypertensive rats (SHRs; n = 72) were studied at different ages stages disease early...
Background: Abnormalities in intracellular calcium (Ca) cycling during Ca overload can cause triggered activity because spontaneous release (SCR) activates sufficient Ca-sensitive inward currents to induce delayed afterdepolarizations (DADs). However, little is known about the mechanisms relating SCR and on tissue scale. Methods Results: Laser scanning confocal microscopy was used measure spatiotemporal properties of within large myocyte populations intact rat heart. Computer simulations...
ABSTRACT Background There are no established predictors of post‐operative atrial fibrillation (POAF) in non‐cardiac thoracic surgery. Pre‐operative left imaging has been shown to identify patients with POAF undergoing cardiac The purpose this study was determine whether pre‐operative strain (LAS) predicts lung resection. Methods One hundred forty‐nine who underwent cancer resection were retrospectively analyzed. involved conventional transthoracic echocardiography comprehensive...
Background: Sudden cardiac death (SCD) studies report higher incidence in men and Black people but presume cause. We sought to identify sex racial differences rates causes of presumed SCDs a prospective postmortem study San Francisco County. Methods: All incident meeting the World Health Organization definition ages 18 90 were autopsied via active surveillance consecutive out-of-hospital deaths POST SCD (Postmortem Systematic Investigation Cardiac Death; February 1, 2011, March 2014)....
Abstract Introduction In patients with chronic idiopathic thrombocytopenic purpura ( cITP ), the platelet count tends to be quite variable and, in majority of cases, specific therapy is not warranted on a regular basis. However, low (<30 nL) or bleeding complications would require therapy, such as prednisolone, intravenous immunoglobulin infusions, splenectomy and/or immunosuppression. Romiplostim, thrombopoietin agonist, has also proven useful improving counts. can associated...
Over 580 000 people in the US experience homelessness, with one of largest concentrations residing San Francisco, California. Unhoused individuals have a life expectancy approximately 50 years, yet how sudden death contributes to this early mortality is unknown.
Spontaneous Coronary Artery Dissection (SCAD) is an important cause of myocardial infarction that typically affects women without traditional cardiovascular risk factors. It the most common in pregnant and postpartum women. SCAD often underdiagnosed due to lack clinician familiarity, patients with pregnancy-associated have more severe clinical presentations than those without. We present a case multiparous woman who presented acute chest pain period.
Spontaneous Leak of Cerebrospinal fluid (CSF) into the middle ear cavity can occur in adults without a history temporal bone trauma or fracture, meningitis any obvious cause, it may result from number congenital deformities ear.Mondini deformity an abnormal development cochlea is frequently associated with CSF leakage therefore clues be lacking that would alert otolaryngologist medial to intact drum are emanating perforation likely fluid.Here we presenting case spontaneous leaks two sites...
7552 Background: Current NCCN guidelines recommend post-operative radiotherapy (PORT) for patients with resected non-small cell lung cancer (NSCLC) N2-involvement. We investigated the relationship between nodal-stage and local-regional recurrence (LR), distant (DR) overall survival (OS) having an R0 resection. Methods: A multi-institutional database of consecutive undergoing R0resection Stages I-IIIA NSCLC from 1998-2009 was used. Patients receiving any radiation therapy before relapse were...
Super Vasmol is one of the commonly used, cheap, freely available hair dye poisoning emerging a major cause suicidal in India, and dyes mainly contain paraphenylene diamine (PPD) resorcinol.Acute by PPD causes characteristic sever angio-neurotic oedema upper air way associated with swollen, dry, hard protruding tongue, systemic intoxication results multisystem involvement can rhabdomyolysis, acute renal failure (ARF).There no specific antidote for treatment supportive, emergency tracheostomy...