A5023657268- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Cancer-related Molecular Pathways
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Medical Imaging and Pathology Studies
- Trauma Management and Diagnosis
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Salivary Gland Tumors Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Respiratory Support and Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Congenital Diaphragmatic Hernia Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Esophageal Cancer Research and Treatment
- Head and Neck Cancer Studies
- Pneumothorax, Barotrauma, Emphysema
- Amoebic Infections and Treatments
- Microtubule and mitosis dynamics
- Cancer and Skin Lesions
- Neuroendocrine Tumor Research Advances
Penn State Milton S. Hershey Medical Center
2014-2024
Baptist Hospital of Miami
2023
Pennsylvania State University
2007-2022
Cancer Institute (WIA)
2000-2022
University of Cincinnati Medical Center
2003-2020
Queen Elizabeth University Hospital
2017
Gartnavel General Hospital
2017
Harvard University
1998-2016
Hershey (United States)
2015
Thoracic Surgery Foundation
2015
A series of about 2200 children who received X-ray treatment for ringworm the scalp (tinea capitis) during 1940s and 1950s, a comparable group 1400 treated without X ray, have been followed by mail questionnaire an average 26 years since to tabulate incidence skin cancer. The consisted 300-380 R five overlapping fields on scalp, cause complete depilation. This delivered doses 300-600 rad various portions with lower face neck. In irradiated group, 41 persons had one or more basal cell...
Rationale: Less invasive, nonsurgical approaches are needed to treat severe emphysema.Objectives: To evaluate the effectiveness and safety of Spiration Valve System (SVS) versus optimal medical management.Methods: In this multicenter, open-label, randomized, controlled trial, subjects aged 40 years or older with severe, heterogeneous emphysema were randomized 2:1 SVS management (treatment) alone (control).Measurements Main Results: The primary efficacy outcome was difference in mean FEV1...
Objective: The aim of this study was to analyze outcomes open lobectomy (OL), VATS, and robotic-assisted (RL). Summary Background Data: Robotic-assisted has seen increasing adoption for treatment early-stage lung cancer. Comparative data regarding these approaches is largely from single-institution case series or administrative datasets. Methods: Retrospective collected 21 institutions 2013 2019. All consecutive cases performed clinical stage IA-IIIA cancer were included. Neoadjuvant...
Serial embolizations of an extremity arteriovenous malformation with alcohol via direct percutaneous punctureWF Yakes, P Pevsner, M Reed, HJ Donohue and N GhaedAudio Available | Share
Background: Colorectal cancer (CRC) metastasectomy improves survival, however most patient develop recurrences. Circulating tumor cells (CTCs) are an independent prognostic marker in stage IV CRC. We hypothesized that CTCs can be enriched during applying different isolation techniques. Methods: 25 CRC patients undergoing liver (16 (64%)) or lung (9 (36%)) were prospectively enrolled (clinicaltrial.gov identifier: NCT01722903). Central venous (liver) radial artery (lung) outflow blood (7.5...
Chronic obstructive pulmonary disease (COPD) is a lethal progressive lung culminating in permanent airway obstruction and alveolar enlargement. Previous studies suggest CTL involvement COPD progression; however, their precise role remains unknown. Here, we investigated whether the activation receptor NK cell group 2D (NKG2D) contributes to development of COPD. Using primary murine epithelium isolated from mice chronically exposed cigarette smoke cultured epithelial cells extract vitro,...
Objective: The aim of this study was to analyze overall survival (OS) robotic-assisted lobectomy (RL), video-assisted thoracoscopic (VATS), and open (OL) performed by experienced thoracic surgeons across multiple institutions. Summary Background Data: Surgeons have increasingly adopted RL for resection early-stage lung cancer. Comparative data following these approaches is largely from single-institution case series or administrative sets. Methods: Retrospective collected 21 institutions...
The synthesis of cyclin D1 and its assembly with cyclin-dependent kinase 4 (CDK4) to form an active complex is a rate-limiting step in progression through the G1 phase cell cycle. Using activated allele mitogen-activated protein 1 (MEK1), we show that this plays significant role positively regulating expression D1. This was found both quiescent serum-starved cells expressing dominant-negative Ras. Despite observation target MEK1, cycling cells, but not D1, capable overcoming arrest induced...
Operative intervention for thoracic trauma typically requires thoracotomy. We hypothesized that thoracoscopy may be safely and effectively utilized the acute management of injuries.The Trauma Registry a Level I center was queried from 1999 through 2010 all video-assisted procedures within 24 h admission. Data collected included initial vital signs, operative indication, intraoperative course, postoperative outcome.Twenty-three patients met inclusion criteria: 3 (13%) following blunt injury...