- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Esophageal and GI Pathology
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Healthcare professionals’ stress and burnout
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Diversity and Career in Medicine
- Cardiac Ischemia and Reperfusion
- Organ Transplantation Techniques and Outcomes
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Transplantation: Methods and Outcomes
- Central Venous Catheters and Hemodialysis
- Pelvic floor disorders treatments
- Congenital Anomalies and Fetal Surgery
- Obsessive-Compulsive Spectrum Disorders
- Anorectal Disease Treatments and Outcomes
- Treatment of Major Depression
- Foreign Body Medical Cases
- Maternal and fetal healthcare
- Mental Health and Psychiatry
- Retirement, Disability, and Employment
University of Michigan–Ann Arbor
2019-2025
Boston Children's Hospital
2025
Harvard University
2025
C. S. Mott Children's Hospital
2019-2025
Michigan Medicine
2019-2024
Columbia University
1990-2023
Regional West Medical Center
2023
ORCID
2022
Michigan United
2019
Women's Hospital
2019
Background Moclobemide, a reversible inhibitor of monoamine oxidase A, previously has been reported to have efficacy in the treatment social phobia. Method Seventy-seven non-responders one week single-blind placebo were randomly assigned moclobemide or for eight weeks double-blind treatment. Outcome was assessed by independent evaluator, treating psychiatrist and self-ratings. After weeks, patients who at least minimally improved continued further weeks. Results Intention-to-treat sample...
<ns4:p><ns4:bold>Background:</ns4:bold> The authors analyzed the distribution of medical student debt and identified demographic features that placed students at high risk for increased financial stress.</ns4:p><ns4:p> <ns4:bold>Methods: </ns4:bold>From April to May 2019, a cross-sectional, anonymous, web-based survey was administered first-year (M1) fourth-year (M4) University Michigan assess literacy, burden, stress, factors. A total 216 680 (32%) completed survey. Respondents voluntarily...
Eight patients with depersonalization disorder or symptoms in association obsessive-compulsive and panic disorders were treated serotonin reuptake blockers. There was clinical overlap of disorder, the co-occurrence features these associated a favorable treatment outcome. The chronicity illness lack prior response to variety treatments highlights positive outcome this treatment. In addition, issues are raised regarding current hierarchical exclusion presence disorders.
Lower-extremity ischemia is a significant complication in children on femoral venoarterial extracorporeal membrane oxygenation (VA ECMO). Our institution currently routinely uses distal perfusion catheters (DPCs) all arterial cannulations attempts to reduce ischemia. We performed single-center, retrospective review of pediatric patients supported with VA ECMO from January 2005 November 2015. The outcomes prophylactic DPC placement at cannulation (prophylactic DPC) were compared historical...
Currently, normothermic ex vivo heart perfusion (NEVHP) is limited to 6-12 hours. NEVHP for 24 hours or more would allow organ treatment, assessment of function, and near-perfect recipient matching. We present a model using continuous hemofiltration (HFn) with sustained myocardial viability up Twenty hearts from 6-10 kg piglets were procured maintained on our circuit. HFn (n = 10) underwent HFn, whereas controls used alone. All vs. four viable at h (p 0.004). At end perfusion, had higher...
Objectives: The purpose of this study was to assess the financial literacy level medical&nbsp;students, evaluate their perceptions about importance literacy, and&nbsp;determine optimal timing and delivery for education. Methods: From April May 2019, a cross-sectional, anonymous, web-based survey administered convenience sample first-year (M1) fourth-year (M4) medical students at University Michigan Medical School, with 216 680 (32%) completing survey. Respondents voluntarily answered...
Extracorporeal life support (ECLS) has grown in its application since first clinical description the 1970s. The technology been used to a wide variety of mechanical modalities and diseases, including respiratory failure, cardiorespiratory cardiac failure. Over many decades safety efficacy studies, followed by randomized trials thousands uses, ECLS is considered as an accepted treatment option for severe pulmonary selected cardiovascular involves use artificial organs, membrane lung blood...
The artificial placenta (AP) promotes organ development and reduces injury in a lamb model of extreme prematurity. This study evaluates hepatic outcomes after AP support with total parenteral nutrition (TPN) administration. Premature lambs (116–121 days estimated gestational age; term = 145) were cannulated for 7 support. Lambs received TPN SMOFlipid (n 7) or Intralipid 5). Liver function compared between the two groups biochemically histologically. Groups by ANOVA Tukey’s multiple...
A radical paradigm shift in the treatment of premature infants failing conventional is to recreate fetal physiology using an extracorporeal Artificial Placenta (AP). The aim this study evaluate effects changing hemoglobin percent (HbF%) on and circuit function during AP support ovine model.
Patients with vestibular fistula have a good functional outcome after posterior sagittal anorectoplasty (PSARP). While continence is often preserved, close follow-up and management of constipation are required. Redo anorectal surgery has been associated worse outcomes compared primary procedures, possibly due to injury scarring the pelvic floor musculature sphincter complex. Our group growing experience in use intraoperative real-time magnetic resonance imaging (MRI) for malformation...
Background: Enterostomies provide fecal diversion for numerous conditions, but anatomical complications-prolapse, stricture, and retraction-occur in up to 25%. Given 76% of these complications require surgical intervention, effective minimally invasive repair techniques their management are needed. This article describes a new technique prolapse utilizing image-guided surgery incisionless ostomy prolapse. Methods: To perform the procedure, prolapsed bowel is reduced evaluated feasibility...
A pumpless artificial lung has the potential to provide a bridge recovery or transplantation in children with respiratory failure. Pulmonary artery inflow and left atrial outflow are necessary for low-gradient, systems; however, long-term cannulation of fragile atrium remains problematic. In this technique, pulmonary were exposed through anterior thoracotomy. Inflow was created using an end-to-side anastomosis artery. Device established atrium. single-stage venous cannula passed free PTFE...
Alpidem, an imidazopyridine that acts at the γ-aminobutyric acid/benzodiazepine receptor complex, has been reported to be effective anxiolytic with a more favorable side effect profile than benzodiazepines. The of alpidem was investigated in 8-week, open, clinical trial 13 patients panic disorder, or without agoraphobia. Three were responders (much improved very much improved), five nonresponders, and dropped out after less 6 weeks treatment. Significant improvement seen sample as whole for...