T. Nakaya

ORCID: 0000-0002-5239-1512
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About
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Research Areas
  • Nutrition, Genetics, and Disease
  • Enhanced Recovery After Surgery
  • Healthcare Regulation
  • Maternal and Neonatal Healthcare
  • Electrolyte and hormonal disorders
  • Cardiac, Anesthesia and Surgical Outcomes
  • Nosocomial Infections in ICU
  • Psychosomatic Disorders and Their Treatments
  • Gout, Hyperuricemia, Uric Acid
  • Thermoregulation and physiological responses
  • Palliative and Oncologic Care
  • Metabolomics and Mass Spectrometry Studies
  • Pain Management and Placebo Effect
  • Biological Research and Disease Studies
  • Healthcare Technology and Patient Monitoring
  • Maternal and Perinatal Health Interventions
  • Vascular Malformations and Hemangiomas
  • Cancer Research and Treatment
  • Neonatal and Maternal Infections
  • Nutrition and Health in Aging
  • Genetic Associations and Epidemiology
  • Burn Injury Management and Outcomes
  • Dental Anxiety and Anesthesia Techniques
  • Vagus Nerve Stimulation Research
  • Hormonal Regulation and Hypertension

Universidade Estadual de Londrina
2018-2024

University of Fukui Hospital
2017-2019

University of Fukui
2015-2017

Saitama International Medical Center
2016

Self-Defense Forces Central Hospital
2007

Kanazawa University
1991-1999

In response to an increase in osmolarity or a decrease plasma volume, surgical patients often experience thirst during the perioperative period. Thirst causes intense discomfort for patients, but nurses and health care providers have received minimal direction on how address this concern. This article presents evidence related advances management of patients' discusses clinical strategies that personnel can safely implement their preoperative postoperative periods. The Study Research Group...

10.1002/aorn.12931 article EN AORN Journal 2020-01-29

Objetivo: Avaliar a prevalência, intensidade e o desconforto da sede no período pós-operatório imediato. Método: Estudo epidemiológico, transversal, descritivo, quantitativo, realizado em um hospital universitário do Sul Brasil, de agosto setembro 2012. A amostra foi composta 386 pacientes recuperação anestésica cirurgias eletivas urgência. Foi utilizado questionário semiestruturado composto dados demográficos, clínicos variáveis relacionadas à sede. Resultados: prevalência 78% (303...

10.5327/z1414-4425201900020006 article PT Revista Sobecc 2019-07-05

<p>Objetivo: avaliar o tempo de jejum pré-operatório, presença e intensidade da sede no pós-operatório imediato. Método: pesquisa documental, quantitativa, descritiva, realizada em 2018, hospital escola, com amostra 749 pacientes. Resultados: médio absoluto foi 15:00 (DP 6:30). Pacientes cirúrgicos urologia apresentaram maior (16:56; DP 9:09). Em relação à faixa etária, variou 13:29 7:34) para crianças, a 15:06 6:32) adultos 15:41 4:37) idosos. A um desconforto presente 84,5% dos...

10.18471/rbe.v32.27679 article PT cc-by-nc Revista Baiana de Enfermagem‏ 2018-12-27

A 59-year-old woman who was known to have large hepatic cysts presented with a positive fecal occult blood test. Her physical examination unremarkable, and laboratory testing revealed no abnormalities. double-contrast barium study showed round, radiolucent area in the descending colon. Colonoscopy light-red, sessile lesion, about 15 mm diameter, which consisted of variously-sized nodules covered white exudate ([Fig. 1]). The rest colonic mucosa unremarkable. When specimen biopsied massive...

10.1055/s-2007-966485 article EN Endoscopy 2007-12-01

To analyze the effects of ice popsicle on vasopressin, osmolality, thirst intensity, and discomfort.This is a quasi-experimental, pre- post-test study conducted in laboratory. The sample consisted nine healthy male volunteers, who received 2% hypertonic saline solution.Popsicle intake did not result statistically significant reduction vasopressin levels (F=0.876 p=0.428). However, there was hormonal physiological profile from 7.1 pg/ml to 5.8 after first two interventions. Osmolality...

10.1590/1983-1447.2021.20190449 article EN cc-by-nc Revista gaúcha de enfermagem 2021-01-01

ABSTRACT Objective: to understand the physiological aspects involved in pre-absorptive thirst satiety based on advances neurophysiology and their applicability healthcare. Method: this is a reflective study that compiles phenomena related form of satiety, describing neurophysiological pathway for satiety. Results: anticipatory mechanisms inhibition are thermoreceptors, osmoreceptors, mechanoreceptors, gastric cognitive mechanisms. The use cold temperature key as its stimuli transmitted...

10.1590/1980-265x-tce-2023-0357en article EN cc-by Texto & Contexto - Enfermagem 2024-01-01

RESUMO Objetivo: Compreender os aspectos fisiológicos envolvidos na saciedade pré-absortiva da sede baseados em avanços neurofisiologia e sua aplicabilidade para a assistência de saúde. Método: estudo reflexivo, que compila fenômenos relacionados forma saciar, descrevendo o caminho neurofisiológico Saciedade Pré-absortiva Resultados: Os mecanismos antecipatórios inibição relacionam-se com termorreceptores, osmorreceptores, mecanorreceptores, gástricos cognitivos. A utilização temperatura...

10.1590/1980-265x-tce-2023-0357pt article PT cc-by Texto & Contexto - Enfermagem 2024-01-01

To implement the preoperative Thirst Management Model, measuring its adoption, coverage, acceptability, feasibility and fidelity by nursing in a burn unit.Quasi-experimental, pre- post-test intervention study. Sample of 59 patients at pre-implementation 40 post-implementation 36 professionals participating implementation unit from August (2019) to March (2020). Statistical analysis used Mann-Whitney Chi-square.Adoption management ranged 0.0% 72.5% post-implementation. The capacity coverage...

10.1590/1983-1447.2022.20220220.en article EN PubMed 2023-01-01

Objetivo: analisar o tempo de jejum e tipo dieta prescrita para reintrodução alimentar no pós-operatório diferentes especialidades cirúrgicas. Método: estudo quantitativo, retrospectivo, documental descritivo dos prontuários pacientes cirúrgicos, com amostra randomizada estratificada 464 pacientes, realizado em hospital universitário público grande porte Paraná. Realizou-se análise estatística descritiva, apresentando medidas tendência central seus intervalos confiança. Resultados: a média...

10.35699/2316-9389.2022.38657 article PT cc-by Reme Revista Mineira de Enfermagem 2022-04-08

Objective: It is well known that the renin angiotensin system (RAS) plays a pivotal role in development of diabetic nephropathy (DMN). Recent genome-wide association studies have identified number common genetic variants associated with blood pressure variation east Asians. One such loci angiotensinase A (ENPEP), which converts II to III RAS. We therefore tested hypothesis ENPEP could show significant prevalence DMN. Design and method: enrolled consecutive 345 subjects who had consulted our...

10.1097/01.hjh.0000491533.03138.28 article EN Journal of Hypertension 2016-08-10

Objective: Calcium channel blocker (CCB) is one of the most useful anti-hypertensive agents without severe adverse effects. However, activation renin-angiotensin system (RAS) unfavorable characteristics CCB in a stand point organ protection. N type calcium thought to be involved renin release via sympathetic and aldosterone from adrenal cortex. Accordingly, N/L has probability less elevation concentrations among CCBs. The objective study compare circulatory RAS levels (plasma activity (PRA),...

10.1097/01.hjh.0000468802.03579.13 article EN Journal of Hypertension 2015-06-01

Objective: Recent genome-wide association studies have identified multiple variants that confer risk of type 2 diabetes mellitus (DM). However, established associations explain only a part the heritability. Thus, even at GWAS era, candidate gene approach should be still useful. interventional against renin angiotensin system (RAS) showed reduction new onset DM, implying is involved in onset. We substantiated hypothesis genetic RAS significant with prevalence DM. Design and method: enrolled...

10.1097/01.hjh.0000468934.73357.4c article EN Journal of Hypertension 2015-06-01

O presente estudo objetivou relatar o isolamento de Pseudonomas aeruginosa resistente à Colistina após tentativas tratar uma pneumonia hospitalar. As informações foram obtidas por meio da revisão do prontuário médico identificação Pseudomonas pelo Laboratório Microbiologia própria instituição. Considerações finais: caso relatado retoma a discussão das dificuldades atuais na terapêutica antimicrobiana destinada infecção hospitalar, principalmente quando acomete pacientes idosos e internados...

10.5433/2316-5200.2013v2n3espp233 article PT BBR - Biochemistry and Biotechnology Reports 2013-08-05

A infeccao hospitalar no paciente recem-nascido e facilitada pela propria condicao de imaturidade do sistema imune. As bacterias multirresistentes sao caracteristicas ambiente hospitalar. O estudo em questao descreve as encontradas culturas positivas pacientes unidade neonatal hospital universitario, assim como a resistencia cada bacteria o material coletado caso. Evidencia-se que ha prevalencia relacao resistentes aos carbapenemicos, sendo Klebsiella pneumoniae MR mais presente nas...

10.5433/2316-5200.2013v2n3espp224 article PT BBR - Biochemistry and Biotechnology Reports 2013-08-05

Objective: The high heritability of plasma renin activity was confirmed in recent investigations. A variation located near the strong enhancer human gene (REN), C-5312T, has been shown to have different transcription levels depending on its allele: 5312T allele shows that are 45% greater than those 5312C allele. purpose this study confirm hypothesis variations region REN involved regulating renal expression renin. Design and method: Sixty-four subjects with biopsy-proven diseases were...

10.1097/01.hjh.0000524037.48627.f7 article EN Journal of Hypertension 2017-07-30

Objective: The renin-angiotensin system (RAS) plays crucial roles in the development of cardiovascular, renal and metabolic conditions. Previous clinical studies have reported that RAS inhibitions organ protective effects a suppressive effect on new onset type 2 diabetes mellitus (T2DM). Recently, novel component RAS, Chromosome 9 Open Reading Frame 3 (C9orf3) which is an aminopeptidase cleaving angiotensin III to generating IV had been identified addition ANPEP characteristics should be...

10.1097/01.hjh.0000523650.67646.13 article EN Journal of Hypertension 2017-07-30

Objective: It is well known that the renin angiotensin system (RAS) plays a pivotal role in development of cardiovascular, renal and metabolic conditions. Angiotensin IV receptor (AT4) newly emerging component RAS. AT4 membrane type aminopeptidase also designated as LNPEP. Actually converts III to further degraded fragments. Thus it thought exerts enzyme action for direction reduction II. We therefore tested hypothesis genetic variants could show significant effects on plasma II...

10.1097/01.hjh.0000523387.81474.55 article EN Journal of Hypertension 2017-07-30

Objective: Uric acid is thought to be one of risk factors for atherosclerotic disorders. The mechanisms have been include endothelial dysfunction, inflammation, oxidative stress and the renin angiotensin system (RAS) activation. It known that RAS plays a pivotal role in However, evidence uric involved activation not sufficient. We therefore tested hypothesis genetic variant transporter, glucose transporter 9 (GLUT9) could show significant association with prevalence hyper-reninemic state....

10.1097/01.hjh.0000539181.62214.8a article EN Journal of Hypertension 2018-06-01

Objective: Hyperuricemia is thought to be one of risk factors for cardiovascular and renal conditions. Several responsible genes gout have been identified including uromodulin (UMOD). UMOD known as the disease gene familial juvenile hypouricemic nephropathy. On other hand, recent GWAS revealed associated with hypertension. We therefore tested hypothesis that a genetic variant could show significant association uric acid (UA) concentrations blood pressure (BP). Design method: enrolled...

10.1097/01.hjh.0000571132.58944.57 article EN Journal of Hypertension 2019-06-22

Objetivo: Avaliar o potencial hidrogeniônico e volume salivar antes depois do uso da goma de mascar mentolada em voluntários saudáveis. Método: Estudo quantitativo, quase-experimental tipo pré-teste pós-teste, realizado com 45 saudáveis entre 18 60 anos. A amostra saliva foi coletada forma não estimulada, seguindo método spitting. O voluntário deveria acumular na boca cuspir num frasco milimetrado, a cada minuto, receber mentolada, por dez minutos etapa. Resultados: Na primeira etapa coleta,...

10.5433/anh.2022v4.id44034 article PT Advances in Nursing and Health 2022-06-24
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