M Nigam

ORCID: 0000-0002-5247-7973
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Structural Anomalies and Repair
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Arrhythmias and Treatments
  • Mechanical Circulatory Support Devices
  • Cardiac and Coronary Surgery Techniques
  • Congenital Heart Disease Studies
  • Pericarditis and Cardiac Tamponade
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Function and Risk Factors
  • Cardiac tumors and thrombi
  • Cardiovascular Conditions and Treatments
  • Cardiovascular and Diving-Related Complications
  • Cardiac Arrest and Resuscitation
  • Blood transfusion and management
  • Tracheal and airway disorders
  • Cardiovascular Issues in Pregnancy
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Aortic Disease and Treatment Approaches
  • Atrial Fibrillation Management and Outcomes
  • Intracranial Aneurysms: Treatment and Complications
  • Airway Management and Intubation Techniques
  • Cancer Diagnosis and Treatment
  • Ubiquitin and proteasome pathways
  • Chemotherapy-induced cardiotoxicity and mitigation

Harvard University
2024

Mass General Brigham
2024

Education and Training Service for Hamburg Businesses
2024

Massachusetts General Hospital
2023

Brigham and Women's Hospital
2023

Burdwan Medical College & Hospital
2013

Govind Ballabh Pant Hospital
1990-2004

University of Pittsburgh
1993

University of Lucknow
1967

The ras oncogene product p21ras requires farnesylation and subsequent plasma membrane association for its transforming activity. This key post-translational modification is catalyzed by farnesyltransferase, which transfers farnesyl from farnesylpyrophosphate to the cysteine of CA1A2X carboxyl-terminal tetrapeptide p21ras. In present report, we describe potent inhibition farnesyltransferase peptidomimetics containing no peptidic amide bonds. We synthesized a series analogues where 2 aliphatic...

10.1016/s0021-9258(19)36832-2 article EN cc-by Journal of Biological Chemistry 1993-10-01

The success with occlusion devices for the closure of atrial septal defects and patent ductus arteriosus prompted transcatheter single multiple muscular ventricular (VSD). procedure VSD was first attempted by Lock et al. in 1988 originally designed other intracardiac (Rashkind umbrella device, clamshell, Cardioseal, coils, Sideris buttoned device etc.) were used a variable rate residual shunt. Recently, specially Amplatzer occluder are use. has been undergoing clinical trial since 1998 after...

10.1111/j.1540-8183.2004.09872.x article EN Journal of Interventional Cardiology 2004-04-01

Autoimmune encephalitis due to glial fibrillar acidic protein (GFAP) astrocytopathy is a rare cause of subacute neuropsychiatric changes. In this case, young patient presented with viral prodrome and meningismus, followed by progressive encephalopathy movement disorders over the span 2 weeks. Due his clinical trajectory, inflammatory cerebrospinal fluid (CSF) analysis, initial normal brain imaging negative serum autoimmune panel, diagnosis was presumed meningoencephalitis. The recurrence...

10.1136/bcr-2024-260628 article EN BMJ Case Reports 2024-05-01

To describe the design, implementation, and evaluation of a nerve block training program for neurology residents.

10.1212/wnl.0000000000206650 article EN Neurology 2024-04-09

To evaluate a simulation case on red flag symptoms and signs of headache for incoming neurology residents.

10.1212/wnl.0000000000205760 article EN Neurology 2024-04-09

A 55 yr. old woman attended emergency with acute intestinal obstruction. The patient underwent surgical procedure of resection after straight X-ray,few haematological and biochemical investigations. On gross examination ileal stricture due to mass in ileocaecal region mesenteric lymph nodes found which on histological came out be a squamous cell carcinoma metastatic deposit node. had hysterectomy done 3&1/2 years back for Stage IIB cervix she received chemoradiation.The obstruction very...

10.3329/bjms.v12i4.16666 article EN cc-by Bangladesh Journal of Medical Science 2013-10-26

Acta Obstet Gynecol Scand 2003; 82: 89–90. © 2003

10.1034/j.1600-0412.2003.820116.x article EN Acta Obstetricia Et Gynecologica Scandinavica 2003-01-01
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