A5025303126- Heart Rate Variability and Autonomic Control
- Diabetes Management and Research
- Diabetes Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes and associated disorders
- Tuberculosis Research and Epidemiology
- Cardiovascular Syncope and Autonomic Disorders
- Blood Pressure and Hypertension Studies
- RNA modifications and cancer
- Tracheal and airway disorders
- Anesthesia and Pain Management
- Lipid metabolism and disorders
- Food Allergy and Anaphylaxis Research
- Mechanical Circulatory Support Devices
- Cancer, Lipids, and Metabolism
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Animal health and immunology
- Economic and Financial Impacts of Cancer
- Cerebrovascular and Carotid Artery Diseases
- Sleep and Work-Related Fatigue
- Surgical Simulation and Training
- Cystic Fibrosis Research Advances
- Medication Adherence and Compliance
Vanderbilt University
2011-2023
Genomics (United Kingdom)
2023
Aintree University Hospitals NHS Foundation Trust
2022
University of Liverpool
2020-2022
University of Sheffield
2014-2021
Sheffield Teaching Hospitals NHS Foundation Trust
2017-2021
Leighton Hospital
2019
Heart Research UK
2017
University of Nevada, Las Vegas
2017
Severn Trent (United Kingdom)
2016
Recent trials of intensive glycemic control suggest a possible link between hypoglycemia and excess cardiovascular mortality in patients with type 2 diabetes. Hypoglycemia might cause arrhythmias through effects on cardiac repolarization changes autonomic activity. Our aim was to study the risk during spontaneous diabetic risk. Twenty-five insulin-treated diabetes history disease or two more factors underwent simultaneous continuous interstitial glucose ambulatory electrocardiogram...
OBJECTIVE Hypoglycemia may exert proarrhythmogenic effects on the heart via sympathoadrenal stimulation and hypokalemia. Hypoglycemia-induced cardiac dysrhythmias are linked to “dead-in-bed syndrome,” a rare but devastating condition. We examined effect of nocturnal daytime clinical hypoglycemia electrocardiogram (ECG) in young people with type 1 diabetes. RESEARCH DESIGN AND METHODS Thirty-seven individuals diabetes underwent 96 h simultaneous ambulatory ECG blinded continuous interstitial...
Background: Sodium-glucose co-transporter-2 (SGLT2) inhibitors have now become established as important second line agents for the management of type 2 diabetes, and are known to clinical glycaemic, renal cardiovascular benefits. The development genital mycotic infections is more common with SGLT2 (overall incidence in trials 4% 6%) compared other oral hypoglycaemic agents, can dissuade patients from persisting treatment. Aims: To determine whether provision hygiene advice beneficial...
We examined whether polymorphisms in interleukin-12B (IL12B) associate with susceptibility to pulmonary tuberculosis (PTB) two West African populations (from The Gambia and Guinea-Bissau) independent from North South America.Nine (seven SNPs, one insertion/deletion, microsatellite) were analyzed 321 PTB cases 346 controls Guinea-Bissau 280 286 Gambia.For replication we studied 281 case 179 control African-American samples 221 144 of European ancestry the US Argentina.First-stage single locus...
<div>Abstract<p><b>Background:</b> African-Americans generally have lower circulating levels of 25 hydroxyvitamin D [25(OH)D] than Whites, attributed to skin pigmentation and dietary habits. Little is known about the genetic determinants 25(OH)D nor whether degree African ancestry associates with 25(OH)D.</p><p><b>Methods:</b> With use a panel 276 informative markers, we estimated European admixture for sample 758 African-American non-Hispanic...
We examined whether polymorphisms in interleukin-12B (IL12B) associate with susceptibility to pulmonary tuberculosis (PTB) two West African populations (from The Gambia and Guinea-Bissau) independent from North South America.Nine (seven SNPs, one insertion/deletion, microsatellite) were analyzed 321 PTB cases 346 controls Guinea-Bissau 280 286 Gambia.For replication we studied 281 case 179 control African-American samples 221 144 of European ancestry the US Argentina.First-stage single locus...
Health care resource utilization and costs may be indicators of disease severity overall health status. In observational studies, these factors could influence patients' probability receiving or benefiting from a particular treatment. We compared pre-index in diabetes patients initiating saxagliptin versus other non-insulin anti-diabetic regimens. Individuals age ≥18 years with evidence T2DM (ICD-9-CM 250.x0 250.x2) were identified US plan database. Patients ≥1 pharmacy claim for (SAXA)...