- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- DNA Repair Mechanisms
- Immune cells in cancer
- Esophageal Cancer Research and Treatment
- Cervical Cancer and HPV Research
- Machine Learning in Bioinformatics
- Histone Deacetylase Inhibitors Research
- Wnt/β-catenin signaling in development and cancer
- Advanced machining processes and optimization
- Hippo pathway signaling and YAP/TAZ
- Cancer-related Molecular Pathways
- Signaling Pathways in Disease
- Epigenetics and DNA Methylation
- Chemotherapy-induced cardiotoxicity and mitigation
- Gastroesophageal reflux and treatments
- Lung Cancer Treatments and Mutations
- CAR-T cell therapy research
- PARP inhibition in cancer therapy
- Immunotherapy and Immune Responses
- Genetic factors in colorectal cancer
- Hedgehog Signaling Pathway Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced Surface Polishing Techniques
North China University of Science and Technology
2021-2024
Changhai Hospital
2023
Second Military Medical University
2023
Sichuan University
2021
West China Hospital of Sichuan University
2021
Bristol-Myers Squibb (United States)
2018-2021
Tongji University
2010-2021
Nankai University
2021
Xi'an Jiaotong University
2021
North China Institute of Science and Technology
2021
Colorectal cancer (CRC) is one of the most commonly diagnosed malignant tumors digestive tract. H2-calponin (CNN2), an actin cytoskeleton-binding protein, isoform calponin protein family whose role in CRC still unknown. Research based on clinical samples showed up-regulation CNN2 and its association with tumor development, metastasis, poor prognosis patients. Both vitro loss-of-function gain-of-function experiments that participates development through influencing cell phenotypes. In vivo,...
Lung cancer, with its high morbidity and mortality, presents a major significant public health challenge. CD147, linked to cancer progression metastasis, is promising therapeutic target, including for lung cancer. The genetic variation may influence the expression of gene consequently risk This study aims investigate single nucleotide polymorphisms (SNPs) in CD147 understand their association developing Han Chinese population.
Lung cancer is primarily classified as NSCLC, which distinguished by a wide range of genetic variations. This study focused on
Human papillomavirus (HPV) vaccine is approved by the U. S. Food and Drug Administration in 2006 for female cancer prevention. There are currently three types of prophylactic HPV vaccines, its application developed countries can significantly reduce infection rates cervical lesion rates. In developing countries, vaccination low due to lack knowledge funds. At same time, concerns about safety have led a reduction countries. Countries facing challenge increasing rates. Key words:...
Abstract Background The middle stages colorectal cancer (CRC) patients are severely differentiated, so suitable biomarkers required to distinguish the cohort with high recurrence risk. We hypothesized that among specimens retained after surgery, those from who relapsed quickly surgery may be more capable find high-risk markers. Methods A lable-free analysis was employed identify candidate proteins markers in CRC tissues within three years since surgery. Combined MEIS3 immunohistochemistry...