A5025230138- Pancreatic and Hepatic Oncology Research
- MRI in cancer diagnosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Artificial Intelligence in Healthcare and Education
- Adrenal and Paraganglionic Tumors
- Medical Imaging Techniques and Applications
- Liver Disease Diagnosis and Treatment
- COVID-19 diagnosis using AI
- Privacy-Preserving Technologies in Data
- Pancreatitis Pathology and Treatment
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Cancer, Hypoxia, and Metabolism
- Esophageal Cancer Research and Treatment
- Hormonal Regulation and Hypertension
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Colorectal Cancer Treatments and Studies
- Ultrasound in Clinical Applications
- Renal cell carcinoma treatment
- Angiogenesis and VEGF in Cancer
Tufts University
2020-2022
Tufts Medical Center
2020
Boston Medical Center
2008-2018
University Medical Center
2016-2018
Boston University
2010-2018
University School
2011
Massachusetts General Hospital
2006-2009
Harvard University Press
2005-2009
Harvard University
2006-2008
Hy-Line (United States)
2007
Purpose: To prospectively assess computed tomographic (CT) perfusion for evaluation of tumor vascularity advanced hepatocellular carcinoma (HCC) and to correlate CT parameters with grade serum markers. Materials Methods: The study was HIPAA compliant approved by the institutional review board. Patients provided informed consent. Thirty patients (22 men, eight women; mean age, 60 years; range, 28–79 years) unresectable or metastatic HCC were studied. Dynamic first-pass performed in primary (n...
Abstract Background. Hepatocellular carcinoma (HCC) is a highly vascularized tumor with poor prognosis. In phase II study that combined bevacizumab gemcitabine and oxaliplatin in advanced HCC, we examined computed tomography perfusion (CTp) scan parameters as surrogate markers of angiogenesis after administration. Methods. HCC patients received alone i.v. at 10 mg/kg on day 1 during cycle 1. CTp scanning was performed baseline days 10–12 to assess changes tissue blood flow (BF), volume (BV),...
The objective of our study was to evaluate a large cohort patients with PET/CT determine whether qualitative (visual) assessment, quantitative standardized uptake value (SUV), or ratio (SUR) techniques should be used when attempting characterize adrenal masses in cancer.The group composed 150 consecutive (78 men, 72 women; mean age, 60 years; range, 24-88 years) documented lesions. All were known have an underlying primary malignancy and referred for the metastatic tumor burden. Definitive...
Abstract Artificial intelligence provides a promising solution for streamlining COVID-19 diagnoses; however, concerns surrounding security and trustworthiness impede the collection of large-scale representative medical data, posing considerable challenge training well-generalized model in clinical practices. To address this, we launch Unified CT-COVID AI Diagnostic Initiative (UCADI), where artificial (AI) can be distributedly trained independently executed at each host institution under...
Abstract Artificial intelligence can potentially provide a substantial role in streamlining chest computed tomography (CT) diagnosis of COVID-19 patients. However, several critical hurdles have impeded the development robust AI model, which include deficiency, isolation, and heterogeneity CT data generated from diverse institutions. These bring about lack generalization model therefore prevent it applications clinical practices. To overcome this, we proposed federated learning-based Unified...
The purpose of this study is to evaluate the added role magnetic resonance imaging (MR) in characterizing subcentimeter focal liver lesion(s) detected on multidetector row helical computed tomography (MDCT).A retrospective analysis was performed 59 noncirrhotic patients with a 4- or 16-slice MDCT. All had gadolinium enhanced MR 1.5-T systems within 6 weeks after Imaging diagnosis graded an ordinal scale 0-5 (0, normal; 1, definitely benign; and 5, malignant). final established either by...
Objectives: To compare low-radiation dose nonenhanced fluorine 18 fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET)/computed (CT) (NE-PET/CT), contrast-enhanced PET/CT (CE-PET/CT), and gadolinium-enhanced liver magnetic resonance imaging (MRI) for the detection characterization of lesions in patients with colorectal cancer (CRC). Methods: In this retrospective review database CRC suspected metastases, 33 (22 men, 11 women; mean age, 63 years) evaluated NE-PET/CT, CE-PET/CT,...
Liver-related illness is increasingly recognized as a source of morbidity in HIV-infected patients. Fatty infiltration the liver potentially an important consequence HIV and treatment with antiretroviral (ARV) therapy. The aim present study was to evaluate men women for hepatic steatosis using noninvasive magnetic resonance spectroscopy (MRS) assess relationship between fat content, insulin resistance, other associated risk factors. We examined 33 consecutively recruited adults without...
Objective: The aim of this study was to assess the potential perfusion computed tomography (CTp) for monitoring induction chemotherapy in patients with squamous cell carcinoma (SCCA) upper aerodigestive tract. Materials and Methods: Twenty-five advanced SCCA underwent CTp volumetric CT before after chemotherapy. Perfusion parameters were calculated tumor, normal tissue, muscles correlated tumor volume. Results: blood flow (BF), volume (BV), permeability surface significantly higher, mean...
In this study we aimed to assess the image quality and degree of vascular enhancement using low-concentration contrast media (LCCM) (300 mg I ml(-1)) high-concentration (HCCM) (370 on 64-slice multidetector row CT (MDCT) abdominal angiography (CTA). addition, feasibility HCCM with a reduced total iodine dose.CTA abdomen MDCT was performed 15 anaesthetised pigs. Study pigs were divided into three groups five each based concentration dose received: Group A (LCCM; 300 ml(-1)), B (HCCM; 370 C...
The purpose of this study is to estimate the optimal time delay before initiation arterial phase scanning for detection hypervascular hepatocellular carcinoma (HCC) on 16-MDCT when a rapid bolus injection contrast medium administered.In prospective study, 25 patients (19 men and six women; mean age, 63.5 years; age range, 50-81 years) with pathologically confirmed HCC were included. Dynamic imaging was performed in cine mode using 70 mL nonionic iodinated (300 mg I/mL) at an rate 7 mL/s....