L. Escudero
A5048077517- Neutrino Physics Research
- Particle physics theoretical and experimental studies
- Astrophysics and Cosmic Phenomena
- Radiomics and Machine Learning in Medical Imaging
- Dark Matter and Cosmic Phenomena
- Particle Detector Development and Performance
- Ovarian cancer diagnosis and treatment
- Atomic and Subatomic Physics Research
- Artificial Intelligence in Healthcare and Education
- AI in cancer detection
- Nuclear Physics and Applications
- Advanced X-ray and CT Imaging
- Particle accelerators and beam dynamics
- Muon and positron interactions and applications
- MRI in cancer diagnosis
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Image Retrieval and Classification Techniques
- Mental Health and Patient Involvement
- Radiology practices and education
- COVID-19 diagnosis using AI
- Electronic Health Records Systems
- Advanced Image and Video Retrieval Techniques
- Medical Coding and Health Information
- Lung Cancer Diagnosis and Treatment
University of Cambridge
2017-2025
Cancer Research UK Cambridge Center
2021-2024
Cancer Research UK
2022-2023
Universitat de València
2011-2016
Instituto de Física Corpuscular
2016
Consejo Superior de Investigaciones Científicas
2014
Unidades Centrales Científico-Técnicas
2014
Colorado State University
2011
The T2K experiment observes indications of ν(μ) → ν(e) appearance in data accumulated with 1.43×10(20) protons on target. Six events pass all selection criteria at the far detector. In a three-flavor neutrino oscillation scenario |Δm(23)(2)| = 2.4×10(-3) eV(2), sin(2)2θ(23) 1 and sin(2)2θ(13) 0, expected number such is 1.5±0.3(syst). Under this hypothesis, probability to observe six or more candidate 7×10(-3), equivalent 2.5σ significance. At 90% C.L., are consistent 0.03(0.04) < 0.28(0.34)...
The T2K experiment has observed electron neutrino appearance in a muon beam produced 295 km from the Super-Kamiokande detector with peak energy of 0.6 GeV. A total 28 events were detected an distribution consistent signal, corresponding to significance 7.3σ when compared 4.92±0.55 expected background events. In Pontecorvo-Maki-Nakagawa-Sakata mixing model, signal depends on several parameters including three angles θ12, θ23, θ13, mass difference Δm232 and CP violating phase δCP. this...
This paper describes the design and construction of MicroBooNE liquid argon time projection chamber associated systems. is first phase Short Baseline Neutrino program, located at Fermilab, will utilize capabilities detectors to examine a rich assortment physics topics. In this document details specifications, assembly procedures, acceptance tests are reported.
We report on measurements of neutrino oscillation using data from the T2K long-baseline experiment collected between 2010 and 2013. In an analysis muon disappearance alone, we find following estimates 68% confidence intervals for two possible mass hierarchies: Normal Hierarchy: $\sin^2\theta_{23}=0.514^{+0.055}_{-0.056}$ $\Delta m^2_{32}=(2.51\pm0.10)\times 10^{-3}$ eV$^2$/c$^4$ Inverted $\sin^2\theta_{23}=0.511\pm0.055$ m^2_{13}=(2.48\pm0.10)\times The accounts multi-nucleon mechanisms in...
The Tokai-to-Kamioka (T2K) experiment studies neutrino oscillations using an off-axis muon beam with a peak energy of about 0.6 GeV that originates at the J-PARC accelerator facility. Interactions neutrinos are observed near detectors placed 280 m from production target and far detector -- Super-Kamiokande (SK) located 295 km away. flux prediction is essential part successful interaction rates T2K important input to oscillation cross section measurements. A FLUKA GEANT3 based simulation...
New data from the T2K neutrino oscillation experiment produce most precise measurement of mixing parameter ${\ensuremath{\theta}}_{23}$. Using an off-axis beam with a peak energy 0.6 GeV and set corresponding to $6.57\ifmmode\times\else\texttimes\fi{}1{0}^{20}$ protons on target, has fit energy-dependent ${\ensuremath{\nu}}_{\ensuremath{\mu}}$ probability determine parameters. The 68% confidence limit ${\mathrm{sin}}^{2}({\ensuremath{\theta}}_{23})$ is...
The T2K collaboration: reports evidence for electron neutrino appearance at the atmospheric mass splitting, |\Delta m_{32}^2|=2.4x10^{-3} eV^2. An excess of interactions over background is observed from a muon beam with peak energy 0.6 GeV Super-Kamiokande (SK) detector 295 km beam's origin. Signal and predictions are constrained by data near detectors located 280 m production target. We observe 11 candidate events SK when 3.3\pm0.4(syst.) expected. background-only hypothesis rejected...
The development and operation of liquid-argon time-projection chambers for neutrino physics has created a need new approaches to pattern recognition in order fully exploit the imaging capabilities offered by this technology. Whereas human brain can excel at identifying features recorded events, it is significant challenge develop an automated, algorithmic solution. Pandora Software Development Kit provides functionality aid design implementation pattern-recognition algorithms. It promotes...
We describe the concept and procedure of drifted-charge extraction developed in MicroBooNE experiment, a single-phase liquid argon time projection chamber (LArTPC). This technique converts raw digitized TPC waveform to number ionization electrons passing through wire plane at given time. A robust recovery from both induction collection anode planes will augment 3D reconstruction, is particularly important for tomographic reconstruction algorithms. building blocks overall are described. The...
T2K has performed the first measurement of ${\ensuremath{\nu}}_{\ensuremath{\mu}}$ inclusive charged current interactions on carbon at neutrino energies $\ensuremath{\sim}1\text{ }\text{ }\mathrm{GeV}$ where is reported as a flux-averaged double differential cross section in muon momentum and angle. The flux predicted by beam Monte Carlo external data, including results from NA61/SHINE experiment. data used for this were taken 2010 2011, with total...
We present several studies of convolutional neural networks applied to data coming from the MicroBooNE detector, a liquid argon time projection chamber (LArTPC). The algorithms studied include classification single particle images, localization and neutrino interactions in an image, detection simulated event overlaid with cosmic ray backgrounds taken real detector data. These demonstrate potential for identification or on interactions. also address technical issues that arise when applying...
The single-phase liquid argon time projection chamber (LArTPC) provides a large amount of detailed information in the form fine-grained drifted ionization charge from particle traces. To fully utilize this information, deposited must be accurately extracted raw digitized waveforms via robust signal processing chain. Enabled by ultra-low noise levels associated with cryogenic electronics MicroBooNE detector, precise extraction induction wire planes LArTPC is qualitatively demonstrated on data...
The low-noise operation of readout electronics in a liquid argon time projection chamber (LArTPC) is critical to properly extract the distribution ionization charge deposited on wire planes TPC, especially for induction planes. This paper describes characteristics and mitigation observed noise MicroBooNE detector. MicroBooNE's single-phase LArTPC comprises two one collection sense plane with total 8256 wires. Current induced each TPC amplified shaped by custom low-power, ASICs immersed...
We have developed a convolutional neural network that can make pixel-level prediction of objects in image data recorded by liquid argon time projection chamber (LArTPC) for the first time. describe design, training techniques, and software tools to train this network. The goal work is develop complete deep based reconstruction chain MicroBooNE detector. show demonstration network's validity on real LArTPC using collection plane images. performed stopping muon...
Abstract High grade serous ovarian carcinoma (HGSOC) is a highly heterogeneous disease that typically presents at an advanced, metastatic state. The multi-scale complexity of HGSOC major obstacle to predicting response neoadjuvant chemotherapy (NACT) and understanding critical determinants response. Here we present framework predict the patients NACT integrating baseline clinical, blood-based, radiomic biomarkers extracted from all primary lesions. We use ensemble machine learning model...
We report a measurement of muon-neutrino disappearance in the T2K experiment. The 295-km beam from Tokai to Kamioka is first implementation off-axis technique long-baseline neutrino oscillation With data corresponding $1.43\ifmmode\times\else\texttimes\fi{}{10}^{20}$ protons on target, we observe 31 fully-contained single $\ensuremath{\mu}$-like ring events Super-Kamiokande, compared with an expectation $104\ifmmode\pm\else\textpm\fi{}14\text{ }(\mathrm{syst})$ without oscillations. best-fit...
The T2K Collaboration reports a precision measurement of muon neutrino disappearance with an off-axis beam peak energy 0.6 GeV. Near detector measurements are used to constrain the flux and cross section parameters. Super-Kamiokande far detector, which is 295 km downstream production target, collected data corresponding $3.01\ifmmode\times\else\texttimes\fi{}{10}^{20}$ protons on target. In absence oscillations, $205\ifmmode\pm\else\textpm\fi{}17$ (syst) events expected be detected while...
We report the first measurement of double-differential and total muon neutrino charged current inclusive cross sections on argon at a mean energy 0.8 GeV. Data were collected using MicroBooNE liquid time projection chamber located in Fermilab Booster beam correspond to 1.6×10^{20} protons target exposure. The measured differential are presented as function momentum, multiple Coulomb scattering momentum technique, angle with respect direction. compare event generators find better agreement...
The observation of the recent electron neutrino appearance in a muon beam and high-precision measurement mixing angle |$\theta _{13}$| have led to re-evaluation physics potential T2K long-baseline oscillation experiment. Sensitivities are explored for CP violation neutrinos, non-maximal |$\sin ^22\theta _{23}$|, octant mass hierarchy, addition measurements |$\delta _{{\rm CP}}$|, ^2\theta |$\Delta m^2_{32}$|, various combinations |$\nu$|-mode |$\bar {\nu }$|-mode data-taking. With an...
Abstract Artificial intelligence provides a promising solution for streamlining COVID-19 diagnoses; however, concerns surrounding security and trustworthiness impede the collection of large-scale representative medical data, posing considerable challenge training well-generalized model in clinical practices. To address this, we launch Unified CT-COVID AI Diagnostic Initiative (UCADI), where artificial (AI) can be distributedly trained independently executed at each host institution under...
Uncertainty quantification in automated image analysis is highly desired many applications. Typically, machine learning models classification or segmentation are only developed to provide binary answers; however, quantifying the uncertainty of can play a critical role for example active human interaction. especially difficult when using deep learning-based models, which state-of-the-art imaging The current approaches do not scale well high-dimensional real-world problems. Scalable solutions...
The T2K off-axis near detector, ND280, is used to make the first differential cross-section measurements of electron neutrino charged current interactions at energies ~1 GeV as a function momentum, scattering angle and four-momentum transfer interaction. total flux-averaged $\nu_e$ on carbon measured be $1.11\pm0.09~(stat)\pm0.18~(syst)\times10^{-38} cm^2/nucleon$. agree with predictions two leading interaction generators, NEUT GENIE. prediction $1.23\times10^{-38} cm^2/nucleon$ GENIE...
The MicroBooNE liquid argon time projection chamber (LArTPC) has been taking data at Fermilab since 2015 collecting, in addition to neutrino beam, cosmic-ray muons. Results are presented on the reconstruction of Michel electrons produced by decay rest abundantly TPC, and given their well known energy spectrum can be used study MicroBooNE's detector response low-energy (electrons with energies up ~ 50 MeV). We describe fully-automated algorithm developed reconstruct electrons, which a sample...