Caitlin Pretz
A5006791475- SARS-CoV-2 detection and testing
- Biosensors and Analytical Detection
- SARS-CoV-2 and COVID-19 Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Mobile Health and mHealth Applications
- Respiratory viral infections research
- Advanced biosensing and bioanalysis techniques
- Asthma and respiratory diseases
- Misinformation and Its Impacts
- Cardiac Health and Mental Health
- Infection Control and Ventilation
- COVID-19 epidemiological studies
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Data-Driven Disease Surveillance
- COVID-19 and Mental Health
- Genetic factors in colorectal cancer
University of Massachusetts Chan Medical School
2022-2025
Guardant (United States)
2023
It is important to document the performance of rapid antigen tests (Ag-RDTs) in detecting SARS-CoV-2 variants.To compare Ag-RDTs Delta (B.1.617.2) and Omicron (B.1.1.529) variants SARS-CoV-2.Secondary analysis a prospective cohort study that enrolled participants between 18 October 2021 24 January 2022. Participants did collected samples for reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.The parent throughout mainland United States through digital...
The performance of rapid antigen tests (Ag-RDTs) for screening asymptomatic and symptomatic persons SARS-CoV-2 is not well established.To evaluate the Ag-RDTs detection among participants.This prospective cohort study enrolled participants between October 2021 January 2022. Participants completed reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.Participants were digitally throughout mainland United States. They self-collected anterior nasal swabs RT-PCR...
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality in the United States. Frequent exacerbations result higher use emergency services hospitalizations, to poor patient outcomes high costs. The objective this study demonstrate feasibility multimodal, community-based intervention treating acute COPD exacerbations. Results Over 18 months, 1,333 patients were approached 100 (7.5%) enrolled (mean age 66, 52% female). Ninety-six...
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and healthcare utilization, with frequent exacerbations contributing to emergency department visits hospitalizations. This study evaluates multimodal, community-based digital health intervention's association changes in acute care utilization among patients COPD develop preliminary estimates intervention effects. In this decentralized, nonrandomized pilot clinical trial, participants moderate severe were offered...
There is a need to understand the performance of rapid antigen tests (Ag-RDT) for detection Delta (B.1.61.7; AY.X) and Omicron (B.1.1.529; BA1) SARS-CoV-2 variants.Participants without any symptoms were enrolled from October 18, 2021 January 24, 2022 performed Ag-RDT RT-PCR every 48 hours 15 days. This study represents non-pre-specified analysis in which we sought determine if sensitivity differed participants with compared variant. Participants who positive on first day testing period...
Performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) varies over the course an infection, and their performance in screening is not well established. We aimed to evaluate Ag-RDT detection symptomatic asymptomatic participants.Participants >2 years old across United States enrolled study between October 2021 February 2022. Participants completed molecular testing (RT-PCR) every 48 hours 15 days. This analysis was limited participants who were tested negative on first day participation....
Abstract Background: Rapid antigen detection tests (Ag-RDT) for SARS-CoV-2 with emergency use authorization generally include a condition of to evaluate the test’s performance in asymptomatic individuals when used serially. We aim describe novel study design that was generate regulatory-quality data serial Ag-RDT detecting virus among individuals. Methods: This prospective cohort siteless, digital approach assess longitudinal Ag-RDT. Individuals over 2 years old from across USA no reported...
Abstract Chronic obstructive pulmonary disease (COPD) is a common, costly, and morbid condition. Pulmonary rehabilitation, close monitoring, early intervention during acute exacerbations of symptoms represent comprehensive approach to improve outcomes, but the optimal means delivering these services uncertain. Logistical, financial, social barriers providing healthcare through face-to-face encounters, paired with recent developments in technology, have stimulated interest exploring...
Background The ongoing SARS-CoV-2 pandemic necessitates the development of accurate, rapid, and affordable diagnostics to help curb disease transmission, morbidity, mortality. Rapid antigen tests are important tools for scaling up testing SARS-CoV-2; however, little is known about individuals’ use rapid at home how facilitate user experience. Objective This study aimed describe feasibility acceptability serial self-testing with SARS-CoV-2, including need assistance reliability...
Rapid antigen tests (Ag-RDT) for SARS-CoV-2 with Emergency Use Authorization generally include a condition of authorization to evaluate the test's performance in asymptomatic individuals when used serially.To describe novel study design generate regulatory-quality data serial use Ag-RDT detecting virus among individuals.Prospective cohort using decentralized approach. Participants were asked test and molecular comparators every 48 hours 15 days.Participants throughout mainland United States...
<title>Abstract</title> Chronic Obstructive Pulmonary Disease (COPD) is a common, costly, and morbid condition. rehabilitation, close monitoring, early intervention during acute exacerbations of symptoms represent comprehensive approach to improve outcomes, but the optimal means delivering these services uncertain. Logistical, financial, social barriers providing healthcare through face-to-face encounters, paired with recent developments in technology, have stimulated interest exploring...
Understanding changes in diagnostic performance after symptom onset and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure within different populations is crucial to guide the use of diagnostics for SARS-CoV-2. The Test Us at Home study was a longitudinal cohort that enrolled individuals across United States between October 2021 February 2022. Participants performed paired antigen-detection rapid tests (Ag-RDTs) reverse-transcriptase polymerase chain reaction (RT-PCR) home...
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality in the United States. Frequent exacerbations result higher use emergency services hospitalizations, to poor patient outcomes high costs.
Abstract Background The performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) in temporal relation to symptom onset or exposure is unknown, as the impact vaccination on this relationship. Objective To evaluate Ag-RDT compared with RT-PCR based day after order decide ‘when test’. Design, Setting, and Participants Test Us at Home study was a longitudinal cohort that enrolled participants over 2 years old across United States between October 18, 2021 February 4, 2022. All were asked...
<sec> <title>BACKGROUND</title> The ongoing pandemic necessitates the development of accurate, rapid, and affordable diagnostics to help curb SARS-CoV-2 disease transmission, morbidity, mortality, as well safely navigate social re-engagement. </sec> <title>OBJECTIVE</title> To describe feasibility acceptability serial self-testing for SARS-CoV-2, including need assistance reliability self-interpretation. <title>METHODS</title> A total 206 adults in United States with Smartphones were...