Carly Herbert
A5074292303- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Biosensors and Analytical Detection
- COVID-19 epidemiological studies
- Respiratory viral infections research
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Data-Driven Disease Surveillance
- Pneumonia and Respiratory Infections
- Child and Adolescent Psychosocial and Emotional Development
- Long-Term Effects of COVID-19
- Energy and Environment Impacts
- Health disparities and outcomes
- Zoonotic diseases and public health
- Community Health and Development
- COVID-19 and Mental Health
- Food Security and Health in Diverse Populations
- Air Quality and Health Impacts
- Bacterial Infections and Vaccines
- Resilience and Mental Health
- Adolescent Sexual and Reproductive Health
- Child Abuse and Trauma
- Advanced biosensing and bioanalysis techniques
- Innovations in Medical Education
- COVID-19 Impact on Reproduction
University of Massachusetts Chan Medical School
2020-2025
Oak Ridge Associated Universities
2024
Environmental Protection Agency
2024
Georgetown University
2024
University of Massachusetts Boston
2023
Washington University in St. Louis
2018
It is important to document the performance of rapid antigen tests (Ag-RDTs) in detecting SARS-CoV-2 variants.To compare Ag-RDTs Delta (B.1.617.2) and Omicron (B.1.1.529) variants SARS-CoV-2.Secondary analysis a prospective cohort study that enrolled participants between 18 October 2021 24 January 2022. Participants did collected samples for reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.The parent throughout mainland United States through digital...
The performance of rapid antigen tests (Ag-RDTs) for screening asymptomatic and symptomatic persons SARS-CoV-2 is not well established.To evaluate the Ag-RDTs detection among participants.This prospective cohort study enrolled participants between October 2021 January 2022. Participants completed reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.Participants were digitally throughout mainland United States. They self-collected anterior nasal swabs RT-PCR...
Pneumococcal conjugate vaccines (PCVs) that are ten-valent (PCV10) and 13-valent (PCV13) became available in 2010. We evaluated their global impact on invasive pneumococcal disease (IPD) incidence all ages. Serotype-specific IPD cases population denominators were obtained directly from surveillance sites using PCV10 or PCV13 national immunisation programmes with a primary series uptake of at least 50%. Annual rate ratios (IRRs) estimated comparing the before any PCV each year post-PCV10...
Abstract Background SARS-CoV-2 rebound, defined as recurrence of a positive test after testing negative during an acute infection, has received attention in patients treated with nirmatrelvir/ritonavir. We examined the association between rebound untreated delayed viral clearance and subsequent self-reported long COVID. Methods From October 2021 to February 2022, Test Us at Home (TUAH) study enrolled 7361 participants self-collect anterior nasal specimens for RT-PCR every 24-48 hours 10-14...
There is a need to understand the performance of rapid antigen tests (Ag-RDT) for detection Delta (B.1.61.7; AY.X) and Omicron (B.1.1.529; BA1) SARS-CoV-2 variants.Participants without any symptoms were enrolled from October 18, 2021 January 24, 2022 performed Ag-RDT RT-PCR every 48 hours 15 days. This study represents non-pre-specified analysis in which we sought determine if sensitivity differed participants with compared variant. Participants who positive on first day testing period...
Performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) varies over the course an infection, and their performance in screening is not well established. We aimed to evaluate Ag-RDT detection symptomatic asymptomatic participants.Participants >2 years old across United States enrolled study between October 2021 February 2022. Participants completed molecular testing (RT-PCR) every 48 hours 15 days. This analysis was limited participants who were tested negative on first day participation....
Abstract Background: Rapid antigen detection tests (Ag-RDT) for SARS-CoV-2 with emergency use authorization generally include a condition of to evaluate the test’s performance in asymptomatic individuals when used serially. We aim describe novel study design that was generate regulatory-quality data serial Ag-RDT detecting virus among individuals. Methods: This prospective cohort siteless, digital approach assess longitudinal Ag-RDT. Individuals over 2 years old from across USA no reported...
Adolescents' risk-taking behaviors can have profound impacts on their future health. Few studies established a relationship between multiple social environmental factors and adolescent risk behaviors. We used structural equation modeling to examine the role of parental monitoring risks adolescents' behavioral intentions
Abstract Introduction The relationship between SARS-CoV-2 viral dynamics during acute infection and the development of long COVID is largely unknown. Methods A total 7361 asymptomatic community-dwelling people enrolled in Test Us at Home parent study October 2021 February 2022. Participants self-collected anterior nasal swabs for RT-PCR testing every 24-48 hours 10-14 days, regardless symptom or status. who had no history COVID-19 enrollment were subsequently found to have ≥1 positive test...
Background The ongoing SARS-CoV-2 pandemic necessitates the development of accurate, rapid, and affordable diagnostics to help curb disease transmission, morbidity, mortality. Rapid antigen tests are important tools for scaling up testing SARS-CoV-2; however, little is known about individuals’ use rapid at home how facilitate user experience. Objective This study aimed describe feasibility acceptability serial self-testing with SARS-CoV-2, including need assistance reliability...
Importance Widespread distribution of rapid antigen tests is integral to the US strategy address COVID-19; however, it estimated that few test results are reported local departments health. Objective To characterize how often individuals in 6 communities throughout United States used a digital assistant log and report them their Design, Setting, Participants This prospective cohort study based on anonymously collected data from beneficiaries Say Yes! Covid Test program, which distributed...
Background: Approximately ten years after seven-valent pneumococcal conjugate vaccine (PCV7) was licensed, PCV10 and PCV13 became available. We evaluated their impacts globally on invasive disease (IPD) incidence in all ages. Methods: Serotype-specific IPD cases population denominators were obtained directly from surveillance sites. Annual rate ratios (IRRs) estimated comparing the pre-any PCV to each post-PCV10/13 year using Bayesian multi-level, mixed effects Poisson regressions, by site...
Legionellosis is a respiratory infection caused by
Shortly after the first case of SARS-CoV-2 was diagnosed a public health emergency (PHE) declared and multi-agency response initiated within US federal government to create propagate testing capacity. As part this response, an unprecedented program designated Rapid Acceleration Diagnostics (RADx) Tech established by National Institutes Health (NIH) facilitate development point-of-care tests for COVID-19. The RADx Clinical Studies Core (CSC), located at University Massachusetts Chan Medical...
Abstract Background Studies suggest that exposure to ambient air pollution during pregnancy may be associated with increased risks of birth defects (BDs), but conclusions have been inconsistent. This study describes the ethnic distribution major BDs and examines relationship between among different groups in Liuzhou city, China. Methods Surveillance data infants born 114 registered hospitals 2019 were analyzed determine epidemiology across five groups. Concentrations six pollutants (PM2.5,...
Abstract Background There is evidence of an association severe coroanavirus disease (COVID-19) outcomes with increased body mass index (BMI) and male sex. However, few studies have examined the interaction between sex BMI on acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral dynamics. Methods Participants conducted RT-PCR testing every 24–48 hours over a 15-day period. Sex were self-reported, Ct values from E-gene used to quantify load. Three distinct using mixed-effects generalized...
Wide-spread distribution of diagnostics is an integral part the United States’ COVID-19 strategy; however, few studies have assessed effectiveness this intervention at reducing transmission community COVID-19.To assess impact Say Yes! Covid Test (SYCT!) Michigan program, a population-based program that distributed 20,000 free rapid antigen tests within Ann Arbor and Ypsilanti, in June-August 2021, on prevalence SARS-CoV-2.This ecological study analyzed cases SARS-CoV-2 from March to...
Serial testing for SARS-CoV-2 is recommended to reduce spread of the virus; however, little known about adherence schedules and reporting practices health departments.The Self-Testing Our Protection from COVID-19 (STOP COVID-19) study aims examine a risk-based strategy using rapid antigen tests test results departments.STOP 12-week digital study, facilitated smartphone app assistance reporting. We are recruiting 20,000 participants throughout United States. Participants stratified into high-...
Rapid antigen tests (Ag-RDT) for SARS-CoV-2 with Emergency Use Authorization generally include a condition of authorization to evaluate the test's performance in asymptomatic individuals when used serially.To describe novel study design generate regulatory-quality data serial use Ag-RDT detecting virus among individuals.Prospective cohort using decentralized approach. Participants were asked test and molecular comparators every 48 hours 15 days.Participants throughout mainland United States...