A5067683880- Acute Myocardial Infarction Research
- SARS-CoV-2 detection and testing
- Diabetes, Cardiovascular Risks, and Lipoproteins
- SARS-CoV-2 and COVID-19 Research
- Chronic Disease Management Strategies
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lipoproteins and Cardiovascular Health
- Biosensors and Analytical Detection
- Mobile Health and mHealth Applications
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- COVID-19 diagnosis using AI
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiac Imaging and Diagnostics
- Cancer, Lipids, and Metabolism
- Respiratory Support and Mechanisms
- Cardiovascular Disease and Adiposity
- Healthcare Systems and Public Health
- Health Promotion and Cardiovascular Prevention
- Cardiac Arrest and Resuscitation
- Obesity and Health Practices
- Electromagnetic wave absorption materials
University of Massachusetts Chan Medical School
2022-2025
Harvard University
2023
Center for Clinical Research (United States)
2023
McLean Hospital
2023
Behavioral Pharma (United States)
2023
Tel Aviv University
1973-2013
Sheba Medical Center
1993-2009
Israel Ministry of Health
2009
Thomas Jefferson University
2009
European Society of Cardiology
2005
The performance of rapid antigen tests (Ag-RDTs) for screening asymptomatic and symptomatic persons SARS-CoV-2 is not well established.To evaluate the Ag-RDTs detection among participants.This prospective cohort study enrolled participants between October 2021 January 2022. Participants completed reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.Participants were digitally throughout mainland United States. They self-collected anterior nasal swabs RT-PCR...
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality in the United States. Frequent exacerbations result higher use emergency services hospitalizations, to poor patient outcomes high costs. The objective this study demonstrate feasibility multimodal, community-based intervention treating acute COPD exacerbations. Results Over 18 months, 1,333 patients were approached 100 (7.5%) enrolled (mean age 66, 52% female). Ninety-six...
The aim of the study was to assess relationship between paroxysmal atrial fibrillation during acute myocardial infarction and long-term prognosis patients after infarction. incidence a trial among 5803 consecutive hospitalized 9.9% (557/5803). Incidence rose with increasing age (≤59 years, 4.2%), (60–69 10.5%), (≥ 70 16.0%) slightly (but not significantly) higher in women (11.0%) than men (9.6%). presence congestive heart failure mean represented two major discriminants (70% 68.6 years)...
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and healthcare utilization, with frequent exacerbations contributing to emergency department visits hospitalizations. This study evaluates multimodal, community-based digital health intervention's association changes in acute care utilization among patients COPD develop preliminary estimates intervention effects. In this decentralized, nonrandomized pilot clinical trial, participants moderate severe were offered...
Stroke complicating acute myocardial infarction is associated with substantial morbidity and mortality. The purpose of this study was to assess the incidence, predictors, impact on mortality stroke/transient ischemic attacks occurring after hospital discharge in a large unselected population survivors.During secondary prevention nifedipine (SPRINT), demographic, anamnestic, clinical data were collected for 5839 consecutive patients admitted 13 coronary care units Israel. Hospital survivors...
Performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) varies over the course an infection, and their performance in screening is not well established. We aimed to evaluate Ag-RDT detection symptomatic asymptomatic participants.Participants >2 years old across United States enrolled study between October 2021 February 2022. Participants completed molecular testing (RT-PCR) every 48 hours 15 days. This analysis was limited participants who were tested negative on first day participation....
Abstract Background: Rapid antigen detection tests (Ag-RDT) for SARS-CoV-2 with emergency use authorization generally include a condition of to evaluate the test’s performance in asymptomatic individuals when used serially. We aim describe novel study design that was generate regulatory-quality data serial Ag-RDT detecting virus among individuals. Methods: This prospective cohort siteless, digital approach assess longitudinal Ag-RDT. Individuals over 2 years old from across USA no reported...
Objective Emergency services utilization is increasing in older adult populations. Many such encounters may be preventable with better access to acute care the community. Mobile integrated health (MIH) programs leverage mobile resources deliver and patients out‐of‐hospital environment have potential improve clinical outcomes decrease costs; however, they not been widely implemented. We assessed barriers, facilitators, other factors critical implementation of MIH key vested partners.
Abstract Chronic obstructive pulmonary disease (COPD) is a common, costly, and morbid condition. Pulmonary rehabilitation, close monitoring, early intervention during acute exacerbations of symptoms represent comprehensive approach to improve outcomes, but the optimal means delivering these services uncertain. Logistical, financial, social barriers providing healthcare through face-to-face encounters, paired with recent developments in technology, have stimulated interest exploring...
OBJECTIVE, DESIGN AND PATIENTS: Between August 1981 and July 1983, 5839 consecutive myocardial infarction patients were hospitalized in 13 coronary care units Israel. The present study examines 10 year survival among 4037 with a first either Q or non-Q waves. Demographic medical data collected from hospital records, 1 clinical follow-up was complete for 99% of survivors. Mortality extended to June 1992 (mean years follow-up).Five hundred eighty (14%) had infarctions the wave type 3457 type....
Importance Widespread distribution of rapid antigen tests is integral to the US strategy address COVID-19; however, it estimated that few test results are reported local departments health. Objective To characterize how often individuals in 6 communities throughout United States used a digital assistant log and report them their Design, Setting, Participants This prospective cohort study based on anonymously collected data from beneficiaries Say Yes! Covid Test program, which distributed...
The present non-intervention screening study was undertaken to explore the relationships between pre-existing low total cholesterol and all-cause mortality. Eleven thousand, five hundred sixty-three patients with coronary heart disease who attended a visit but were not included in Bezafibrate Infarction Prevention followed-up for mean of 3·3 years after determination baseline cholesterol. Five ninety-five (5%) this largely unselected population had levels ≤ 160 mg. dl−1 formed population....
Shortly after the first case of SARS-CoV-2 was diagnosed a public health emergency (PHE) declared and multi-agency response initiated within US federal government to create propagate testing capacity. As part this response, an unprecedented program designated Rapid Acceleration Diagnostics (RADx) Tech established by National Institutes Health (NIH) facilitate development point-of-care tests for COVID-19. The RADx Clinical Studies Core (CSC), located at University Massachusetts Chan Medical...
Women sustaining myocardial infarction fare worse than men during hospitalization. Reports on long-term survival in women surviving art acute are controversial. The Secondary Prevention Reinfarction Israeli Nifedipine Trial (SPRINT) registry includes 5,839 consecutive patients who were hospitalized 13 coronary care units Israel between 1981 and 1983. authors examined sex differences the of 4,808 hospital survivors (1,120 3,688 men). exhibited a significantly poorer men. After age adjustment,...
Rapid antigen tests (Ag-RDT) for SARS-CoV-2 with Emergency Use Authorization generally include a condition of authorization to evaluate the test's performance in asymptomatic individuals when used serially.To describe novel study design generate regulatory-quality data serial use Ag-RDT detecting virus among individuals.Prospective cohort using decentralized approach. Participants were asked test and molecular comparators every 48 hours 15 days.Participants throughout mainland United States...
Rodent vendors are often utilized interchangeably, assuming that the phenotype of a given strain remains standardized between colonies. Several studies, however, have found significant behavioral and physiological differences Sprague Dawley (SD) rats from separate vendors. Prepulse inhibition startle (PPI), form sensorimotor gating in which low-intensity leading stimulus reduces response to subsequent stimulus, may also vary by vendor. Differences PPI rat strains well known, but divergence...