A5017527636- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Biosensors and Analytical Detection
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mobile Health and mHealth Applications
- COVID-19 diagnosis using AI
- Geriatric Care and Nursing Homes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Chronic Disease Management Strategies
- Respiratory Support and Mechanisms
- Disaster Response and Management
- Diabetes Management and Research
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Restraint-Related Deaths
- Sepsis Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Healthcare Decision-Making and Restraints
- Opioid Use Disorder Treatment
- Nursing Diagnosis and Documentation
- Health Policy Implementation Science
- Electronic Health Records Systems
- COVID-19 epidemiological studies
University of Massachusetts Chan Medical School
2020-2025
UMass Memorial Health Care
2025
Boston Medical Center
2018-2020
Florida Atlantic University
2020
South Shore Hospital
2020
Golden Gate University
2014
Mentor
2009
Royal Society of Arts
2009
University of Cambridge
1993
It is important to document the performance of rapid antigen tests (Ag-RDTs) in detecting SARS-CoV-2 variants.To compare Ag-RDTs Delta (B.1.617.2) and Omicron (B.1.1.529) variants SARS-CoV-2.Secondary analysis a prospective cohort study that enrolled participants between 18 October 2021 24 January 2022. Participants did collected samples for reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.The parent throughout mainland United States through digital...
The performance of rapid antigen tests (Ag-RDTs) for screening asymptomatic and symptomatic persons SARS-CoV-2 is not well established.To evaluate the Ag-RDTs detection among participants.This prospective cohort study enrolled participants between October 2021 January 2022. Participants completed reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours 15 days.Participants were digitally throughout mainland United States. They self-collected anterior nasal swabs RT-PCR...
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality in the United States. Frequent exacerbations result higher use emergency services hospitalizations, to poor patient outcomes high costs. The objective this study demonstrate feasibility multimodal, community-based intervention treating acute COPD exacerbations. Results Over 18 months, 1,333 patients were approached 100 (7.5%) enrolled (mean age 66, 52% female). Ninety-six...
There is a need to understand the performance of rapid antigen tests (Ag-RDT) for detection Delta (B.1.61.7; AY.X) and Omicron (B.1.1.529; BA1) SARS-CoV-2 variants.Participants without any symptoms were enrolled from October 18, 2021 January 24, 2022 performed Ag-RDT RT-PCR every 48 hours 15 days. This study represents non-pre-specified analysis in which we sought determine if sensitivity differed participants with compared variant. Participants who positive on first day testing period...
Digital mental health interventions, such as artificial intelligence (AI) conversational agents, hold promise for improving access to care by innovating therapy and supporting delivery. However, little research exists on patient perspectives regarding AI which is crucial their successful implementation. This study aimed fill the gap exploring patients' perceptions acceptability of agents in healthcare. Adults with self-reported mild moderate anxiety were recruited from UMass Memorial Health...
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and healthcare utilization, with frequent exacerbations contributing to emergency department visits hospitalizations. This study evaluates multimodal, community-based digital health intervention's association changes in acute care utilization among patients COPD develop preliminary estimates intervention effects. In this decentralized, nonrandomized pilot clinical trial, participants moderate severe were offered...
Background: Chronic obstructive pulmonary disease (COPD) is a common and impactful that the target of large portfolio clinical research. However, there limited understanding how individuals with COPD perceive trial designs, outcomes, intervention acceptability. The objective this project was to explore perspectives priorities patients their caregivers toward COPD-focused Methods: Semi-structured interviews were conducted participants living using Theoretical Framework Acceptability (TFA)...
Sepsis is a common, critical, time-sensitive medical emergency, with mortality rates of up to 56%. Early antibiotic administration cornerstone sepsis management, yet prehospital remains uncommon in the United States. This prospective observational study evaluated implementation protocol an urban EMS system. Patients were eligible for if they ≥18 years old, hypotensive (SBP < 90 mm Hg), and febrile or hypothermic (<96.8°F >100.4°F). Paramedics drew blood cultures administered...
Abstract Background Poor care access and lack of proper triage medical complaints leads to inappropriate use acute resources. Mobile integrated health (MIH) programs may offer a solution by providing adaptable on‐demand care. There is little information describing that manage undifferentiated in the community. The objective this study was assess safety feasibility an MIH program responds community older adults. Methods This prospective observational examining pilot program. Seven ambulatory...
Abstract Background: Rapid antigen detection tests (Ag-RDT) for SARS-CoV-2 with emergency use authorization generally include a condition of to evaluate the test’s performance in asymptomatic individuals when used serially. We aim describe novel study design that was generate regulatory-quality data serial Ag-RDT detecting virus among individuals. Methods: This prospective cohort siteless, digital approach assess longitudinal Ag-RDT. Individuals over 2 years old from across USA no reported...
The goal of this study is to describe complications and outcomes prehospital ketamine use for agitation as compared other methods physical or chemical restraint such haloperidol plus benzodiazepine only.We conducted a single-center retrospective review patient encounters in which was administered the setting. At beginning our window, only available paramedics managing agitated patients but subsequently, benzodiazepines were introduced, followed by 2 years later. By comparing before after...
Performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) varies over the course an infection, and their performance in screening is not well established. We aimed to evaluate Ag-RDT detection symptomatic asymptomatic participants.Participants >2 years old across United States enrolled study between October 2021 February 2022. Participants completed molecular testing (RT-PCR) every 48 hours 15 days. This analysis was limited participants who were tested negative on first day participation....
Objective Emergency services utilization is increasing in older adult populations. Many such encounters may be preventable with better access to acute care the community. Mobile integrated health (MIH) programs leverage mobile resources deliver and patients out‐of‐hospital environment have potential improve clinical outcomes decrease costs; however, they not been widely implemented. We assessed barriers, facilitators, other factors critical implementation of MIH key vested partners.
Abstract Chronic obstructive pulmonary disease (COPD) is a common, costly, and morbid condition. Pulmonary rehabilitation, close monitoring, early intervention during acute exacerbations of symptoms represent comprehensive approach to improve outcomes, but the optimal means delivering these services uncertain. Logistical, financial, social barriers providing healthcare through face-to-face encounters, paired with recent developments in technology, have stimulated interest exploring...
Importance Widespread distribution of rapid antigen tests is integral to the US strategy address COVID-19; however, it estimated that few test results are reported local departments health. Objective To characterize how often individuals in 6 communities throughout United States used a digital assistant log and report them their Design, Setting, Participants This prospective cohort study based on anonymously collected data from beneficiaries Say Yes! Covid Test program, which distributed...
Background Burnout is costly to the healthcare system and associated with medical error, absenteeism, attrition. Emergency services (EMS) clinicians endure numerous stressors that predispose them experience burnout.
Shortly after the first case of SARS-CoV-2 was diagnosed a public health emergency (PHE) declared and multi-agency response initiated within US federal government to create propagate testing capacity. As part this response, an unprecedented program designated Rapid Acceleration Diagnostics (RADx) Tech established by National Institutes Health (NIH) facilitate development point-of-care tests for COVID-19. The RADx Clinical Studies Core (CSC), located at University Massachusetts Chan Medical...
Abstract Background: Agitated behaviors are frequently encountered in the prehospital setting and require emergent treatment to prevent harm patients personnel. Chemical sedation with ketamine works faster than traditional pharmacologic agents, though it has a higher incidence of adverse events, including intubation. Outcomes following varying initial doses intramuscular (IM) use have been incompletely described. Objective: To determine whether using lower dose IM protocol for agitation is...
Rapid antigen tests (Ag-RDT) for SARS-CoV-2 with Emergency Use Authorization generally include a condition of authorization to evaluate the test's performance in asymptomatic individuals when used serially.To describe novel study design generate regulatory-quality data serial use Ag-RDT detecting virus among individuals.Prospective cohort using decentralized approach. Participants were asked test and molecular comparators every 48 hours 15 days.Participants throughout mainland United States...
Louise O’Connor is a Trustee for Mentor UK, and an Independent Consultant. As former Head of the Drugs Education Prevention Research Unit (DEPRU) at University Surrey, Roehampton, (now Roehampton University) has published number books research reports examining effectiveness drugs prevention education approaches, multi-agency partnerships, school health education. These include seminal report which subsequently influenced ACPO Government policy on drug in schools, ‘Drug Schools: Identifying...
Introduction: There is concern about the initiation of opiates in healthcare settings due to risk future misuse. Although opiate medications have historically been at core prehospital pain management, several states are introducing non-opiate alternatives care. Prior studies suggest that analgesics non-inferior for many acute complaints, yet there little literature describing practice patterns management Our goal was describe and attitudes paramedics toward after introduction non-opiates a...