- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Sexuality, Behavior, and Technology
- Syphilis Diagnosis and Treatment
- COVID-19 and Mental Health
- HIV/AIDS oral health manifestations
- LGBTQ Health, Identity, and Policy
- SARS-CoV-2 and COVID-19 Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Advanced Computing and Algorithms
- HIV-related health complications and treatments
- Cervical Cancer and HPV Research
- COVID-19 Clinical Research Studies
- Reproductive tract infections research
- Respiratory Support and Mechanisms
- ECG Monitoring and Analysis
- Hepatitis B Virus Studies
- COVID-19 epidemiological studies
- Mobile Health and mHealth Applications
- Adolescent Sexual and Reproductive Health
- Pharmacological Effects and Toxicity Studies
- Memory and Neural Mechanisms
- HIV/AIDS drug development and treatment
- EEG and Brain-Computer Interfaces
Ningbo Center for Disease Control and Prevention
2023-2025
University of Massachusetts Chan Medical School
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2023
Shenyang Center for Disease Control and Prevention
2020-2023
China Medical University
2020-2023
First Hospital of China Medical University
2023
South China Institute of Collaborative Innovation
2023
National Health and Family Planning Commission
2022
The University of Texas at Arlington
2022
Wenzhou Medical University
2019
<h3>Importance</h3> Evidence on HIV preexposure prophylaxis (PrEP) among Chinese men who have sex with (MSM) is critical to guide its large-scale implementation in low- and middle-income countries. <h3>Objective</h3> To evaluate incident infection, adherence, safety, changes sexual behaviors MSM using daily PrEP (D-PrEP) event-driven (ED-PrEP) 4 cities China. <h3>Design, Setting, Participants</h3> This nonrandomized controlled trial was conducted HIV-seronegative from December 11, 2018,...
There are mixed findings in the literature regarding association between HIV status and risk of COVID-19 infection. Thus, we aimed to estimate characteristics infection Infection a Chinese sample. We conducted cross-sectional survey 1995 people living with (PLWH) 3503 HIV-negative adults Ningbo, China. compared prevalence rates SARS-CoV-2 long nucleic acid conversion time (more than 2 weeks) among PLWH participants, respectively. In addition, explored factors associated two groups. Overall,...
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and healthcare utilization, with frequent exacerbations contributing to emergency department visits hospitalizations. This study evaluates multimodal, community-based digital health intervention's association changes in acute care utilization among patients COPD develop preliminary estimates intervention effects. In this decentralized, nonrandomized pilot clinical trial, participants moderate severe were offered...
The progressive nature of Alzheimer's disease (AD) highlights the importance predicting lifetime risk and updating assessments as new data emerge. This study aimed to develop a dynamic model using longitudinal cognitive for updated predictions. used from Religious Orders Study Rush Memory Aging Project (ROSMAP) prediction based on five domains, annually over 10 years. models 2384 participants showed improved area under curve (AUC) time, rising 0.578 at baseline 0.765 with years data. AD...
Background Men who have sex with men (MSM) are disproportionately affected by sexually transmitted infections (STIs). We sought to describe patterns of co-infections and explore factors associated increased acquisition STIs among MSM. Methods enrolled MSM in Shenyang, China, between July December 2020 test for four STIs, including human papillomavirus (HPV), Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Treponema pallidum (TP). Data regarding demographic behavioral characteristics...
Background: Despite the insupportable burden caused by human papillomavirus (HPV) and high vaccine acceptability, vaccination programs are not currently available for men who have sex with (MSM). We aimed to assess HPV infection examining willingness among MSM cost-effectiveness of Chinese 2-valent vaccine. Methods: recruited in Shenyang, China between July December 2020 conduct anal testing an online survey regarding HPV-related knowledge acceptability. performed a analysis evaluate...
Pre-exposure prophylaxis (PrEP) is an effective HIV prevention measure. Clinicians play a crucial role in PrEP implementation, and their knowledge, attitudes, career experience may affect willingness to prescribe PrEP. However, little known about the attitudes of clinicians countries without PrEP-specific guidelines.We aimed determine factors associated with being willing China.Between May June 2019, we conducted online cross-sectional survey 31 provinces across six administrative regions...
Abstract Background There are mixed findings in the literature regarding association between HIV status and risk of COVID-19 infection. Thus, we aimed to estimate characteristics infection Infection a Chinese sample. Methods We conducted cross-sectional survey 1995 people living with (PLWH) 3503 HIV-negative adults Ningbo, China. compared prevalence rates SARS-CoV-2 long nucleic acid conversion time (more than 2 weeks) among PLWH participants, respectively. In addition, explored factors...
Background To date, no randomized controlled trials have specifically addressed behavior changes after HIV self-testing (HIVST) among transgender women. Objective This study aims to evaluate the effects of HIVST on in testing behavior, frequency condomless sex, and partner numbers women China. Methods Participants were recruited from 2 Chinese cities using both online offline methods. Transgender randomly assigned receive an intervention. Data previous 3 months collected at baseline, months,...
<sec> <title>BACKGROUND</title> To date, no randomized controlled trials have specifically addressed behavior changes after HIV self-testing (HIVST) among transgender women. </sec> <title>OBJECTIVE</title> This study aims to evaluate the effects of HIVST on in testing behavior, frequency condomless sex, and partner numbers women China. <title>METHODS</title> Participants were recruited from 2 Chinese cities using both online offline methods. Transgender randomly assigned receive an...
Nonoccupational postexposure prophylaxis (nPEP) is an effective HIV biomedical prevention strategy. The research and use of nPEP are mainly concentrated in the developed world, while little known about knowledge, attitudes, practices among medical care providers developing countries.
<sec> <title>BACKGROUND</title> Men who have sex with men (MSM) high HIV incidence and prevalence burdens but relatively low testing rates. Literature showed insufficient evidence on the efficacy of Social media (WeChat) based self-testing (HIVST) kits distribution approaches among MSM their sexual partners. </sec> <title>OBJECTIVE</title> This study evaluated an HIVST intervention in increasing uptake partners China. <title>METHODS</title> The used a 12-month stepped-wedge randomized...
No randomized controlled trials have involved established HIV-diagnosed men who sex with (MSM) diagnosed for more than 6 months into the assisted partner service (aPS). We compared voluntary aPS involving community-based organizations (CBOs) and HIV self-testing (aPSST) regular (rPS) in MSM irrespective of diagnosis time.In this unblinded, multicentre trial, we enrolled time three cities northern China. Index patients were randomly assigned to aPSST or rPS. group additionally provided a...
Objective: To explore the mediation mechanism of coronary artery lesion among both male and female Kawasaki disease (KD) children. Methods: Children with KD that hospitalized in Wenzhou Medical University affiliated Yuying Children's Hospital from January 2009 to December 2014, were included this study. Differences on demographical characteristics, clinical manifestations, laboratory indicators, regimen time treatment, results pre/post echocardiography treatment between patients, compared....
<sec> <title>BACKGROUND</title> Nonoccupational postexposure prophylaxis (nPEP) is an effective HIV biomedical prevention strategy. The research and use of nPEP are mainly concentrated in the developed world, while little known about knowledge, attitudes, practices among medical care providers developing countries. </sec> <title>OBJECTIVE</title> We aimed to assess knowledge prescribing practice mainland China. <title>METHODS</title> were recruited China during May June 2019 through online...
<sec> <title>BACKGROUND</title> Pre-exposure prophylaxis (PrEP) is an effective HIV prevention measure. Clinicians play a crucial role in PrEP implementation, and their knowledge, attitudes, career experience may affect willingness to prescribe PrEP. However, little known about the attitudes of clinicians countries without PrEP-specific guidelines. </sec> <title>OBJECTIVE</title> We aimed determine factors associated with being willing China. <title>METHODS</title> Between May June 2019, we...