A5041482465- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Anesthesia and Pain Management
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Bone and Joint Diseases
- Blood transfusion and management
- Bone fractures and treatments
- Muscle and Compartmental Disorders
- Hip and Femur Fractures
- Nausea and vomiting management
- Nerve injury and regeneration
- Pelvic and Acetabular Injuries
- Inflammatory mediators and NSAID effects
- Medical Imaging and Analysis
- Bone health and treatments
- Child Abuse and Related Trauma
- Cardiac, Anesthesia and Surgical Outcomes
- Mesenchymal stem cell research
- Synthesis of β-Lactam Compounds
- Shoulder Injury and Treatment
- Cervical and Thoracic Myelopathy
- Anesthesia and Sedative Agents
West China Hospital of Sichuan University
2005-2020
Sichuan University
2009-2020
Taihe Hospital
2008
Neural stem cells (NSCs) have emerged as a potential source for cell replacement therapy following spinal cord injury (SCI). However, poor survival and low neuronal differentiation remain major obstacles to the use of NSCs. Biomaterials with neurotrophic factors are promising strategies promoting proliferation Silk fibroin (SF) matrices were demonstrated successfully deliver growth preserve their potency. In this study, by incorporating NT-3 into SF coating, we developed NT-3-immobilized...
A series study of patients with lower cervical facet dislocation accompanied by traumatic disc herniation treated anterior decompression and nonstructural bone grafting posterior fixation.To describe a surgical technique fixation its clinical outcome in group herniation.The optimal treatment for prolapsed is still controversial.After discectomy endplate preparation, layer morselized cancellous grafts from the iliac crest was placed interspace, held appropriate sagittal position 2 layers...
This study was designed to evaluate the effects of combined treatment with an anti-coagulant (enoxaparin) agent and a lipid-lowering (lovastatin) on prevention or decrease in occurrence steroid-induced osteonecrosis rabbits. A total 112 rabbits, which were injected intramuscularly 20 mg/kg methylprednisolone acetate divided into four groups treated as follows: one group received enoxaparin lovastatin (EL; n = 30), another alone (EA; 28), (LA; 28) last no (non-prophylactic; NP, 26)....
Little has been published on blood management in total hip and knee arthroplasty (THA TKA, respectively) patients focusing both hematopoiesis hemostasis. Our aim was to explore the effectiveness safety of an optimized program THA TKA a large, single-center, retrospective study. We retrospectively reviewed consecutive primary unilateral patients’ data at our institution through National Health Database. They were divided into 3 groups according program: group A—combined use intravenous...
This retrospective cohort study aimed to compare the total hospital cost, length of stay (LOS), and incidence complications between simultaneous bilateral hip arthroplasty (simBTHA) staged (staBTHA).We identified 256 patients who underwent staBTHA matched them a control group simBTHA from 2013 2016. Patients' demographics, costs, complication rates, LOS were recorded compared.Patients undergoing younger (52.0 ± 12.0 vs 54.9 13.2 years, P = .01), more likely be men (55.9% 46.9%, .04). There...
Objectives To evaluate the morphine-sparing effects of sequential treatment versus placebo in subjects undergoing total knee arthroplasty (TKA), on pain relief, inflammation control and functional rehabilitation after TKA safety. Design Double-blind, pragmatic, randomised, placebo-controlled trial. Setting Four tertiary hospitals China. Participants 246 consecutive patients who underwent elective unilateral because osteoarthritis (OA). Interventions Patients were randomised 1:1 to...
This study aimed to compare the efficacy and safety of different tranexamic acid (TXA) routes following primary total hip arthroplasty (THA).We collected data from National Health Database on patients registered January 2013 September 2017. The were divided based TXA administration route into a control group (without TXA), intravenous group, topical combined group. outcome was transfusion; secondary outcomes blood loss, haemoglobin level, decrease in postoperative day 3, incidence...
Object The role of oxygen in disc metabolism remains a matter debate. Whether the effect hypoxic priming on nucleus pulposus phenotype can be maintained vivo is not clear. goal present study was to test hypothesis that low tension vitro could promote vivo. Methods Bovine cells were seeded 3D scaffolds and subjected varying tensions (2% 20%) for 3 weeks. constructs then implanted subcutaneously 8 Changes extracellular matrix evaluated using quantitative real-time reverse transcriptase...
Introduction Total knee arthroplasty (TKA) has been regarded as a most painful orthopaedic surgery. Although many surgeons sequentially use parecoxib and celecoxib routine strategy for postoperative pain control after TKA, high quality evidence is still lacking to prove the effect of this sequential regimen, especially at medium-term follow-up. The purpose study, therefore, evaluate efficacy safety intravenous sodium followed by oral in patients with osteoarthritis (OA) undergoing TKA....
Objective To investigate the status of primary osteoarthritis in population aged 40 years and over China. Methods Six centers were selected from China which are Shijiazhuang, Harbin, Shanghai, Guangzhou, Chengdu Xi'an. The objective study included general Han nationality over. In every center, 1 000 people sampled according to principles hierarchy, multistage cluster random sampling; urban rural areas as well male female accounted for half ratio respectively. For diagnostic criteria...
To investigate the efficacy of sequential treatment with adductor canal nerve block (ACNB) and cyclooxygenase 2 (COX-2) selective inhibitor (parecoxib celecoxib) after primary total knee arthroplasty (TKA).Between January 2015 December 2015, 90 osteoarthritis patients who met inclusion criteria were treated, randomly divided into 3 groups:ACNB+COX-2 group (group A, n=30), COX-2 B, control C, n=30). There was no significant difference in gender, age, body mass index, side, duration between...
To evaluate the effectiveness and safety of restrictive fluid therapy combined with preoperative urination training during perioperative period in an enhanced recovery after surgery (ERAS) program for primary total hip arthroplasty (THA).A retrospective study were conducted 73 patients who underwent unilateral THA liberal intravenous on day between April 2015 March 2016 (control group) 70 November 2017 (trial group). There was no significant difference gender, age, weight, height, body mass...
Abstract Background We sought to determine (1) whether the addition of prophylactic oral mosapride a protocol including dexamethasone and ondansetron further reduces postoperative nausea vomiting (PONV) compared with alone or combination both; (2) preemptive application provides additional clinical benefits for bowel function appetite, thus improving functional recovery. Methods randomized 240 patients undergoing total hip knee arthroplasty receive placebo (Control, n = 80), (10 mg) before...