- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Advanced MRI Techniques and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiomyopathy and Myosin Studies
- Cardiovascular Disease and Adiposity
- Lipoproteins and Cardiovascular Health
- Cardiac pacing and defibrillation studies
- Pericarditis and Cardiac Tamponade
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Analytical Methods in Pharmaceuticals
- Vascular anomalies and interventions
- Global Public Health Policies and Epidemiology
- Cardiac, Anesthesia and Surgical Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Brain Tumor Detection and Classification
- Genetics and Physical Performance
- Neurological Disorders and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
Institut Penyelidikan Veterinar
2019-2024
Ministry of Health
2023
Rijnstate Hospital
2021-2022
Sarawak Biodiversity Centre
2017-2022
Sarawak General Hospital
2014-2022
Flinders Medical Centre
2015
Troponin-positive chest pain patients with unobstructed coronaries represent a clinical dilemma. Cardiovascular magnetic resonance (CMR) imaging has an increasingly prominent role in the assessment of these patients; however, its utility addition to expert judgement is unclear. We sought determine incremental diagnostic value CMR and heterogeneity diagnoses by experienced cardiologists when presented blinded investigative data this population.A total 125 consecutive presenting tertiary...
Abstract Aims Heart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Failure (MY‐HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of identify areas for improvement within national services. Methods results MY‐HF 3‐year prospective, observational study comprising 2717 admitted acute HF. We report description baseline at admission outcomes index hospitalization these patients. mean...
Patients undergoing elective percutaneous coronary intervention (PCI) with drug-eluting stents (DES) who have impaired clopidogrel response, a higher risk of subsequent major adverse cardiovascular events (MACE).To establish the relationship between CYP2C19 genotype, responsiveness and 1-year MACE.Aspirin/clopidogrel responses were assessed Multiplate Analyzer CYP2C19*2 allele by SpartanRx.A total 42.0% carried ≥1 allele. Prevalences aspirin high on-treatment platelet reactivity (HPR; local...
Acute myocardial infarction (AMI) is associated with heightened thrombin generation. There are limited data relating to generation and left ventricular (LV) scarring LV dilatation in post-MI remodeling. We studied 113 patients ST-segment elevation (STEMI) who had undergone primary percutaneous coronary intervention (PPCI) (n = 76) or pharmaco-invasive management (thrombolysis followed by early PCI, n 37). Endogenous potential (ETP) was measured at baseline, 1 month 6 months. Cardiovascular...
Although the burden of premature myocardial infarction (MI) is high in Malaysia, direct evidence on determinants MI this multi-ethnic population remains sparse.The Malaysian Acute Vascular Events Risk (MAVERIK) study a retrospective case-control established to investigate genomic, lipid-related, and other acute Malaysia. In paper, we report protocol early results.By June 2019, had enrolled approximately 2500 patients with their first controls without cardiovascular disease, who were...
Background and Objectives: The aims of this study were (1) to examine the diagnostic accuracy resting time-averaged distal coronary pressure (Pd) mean aortic (Pa) ratio predict hyperemic fractional flow reserve (FFR) (2) identify a Pd/Pa value that can preclude need for FFR assessed with use monorail catheter. Methods: A total 191 stenoses assessed. After exclusions, 157 data sets from 103 patients analyzed. Results: Resting showed poor agreement ( r =0.619, P<0.001). receiver operating...
Background: N-terminal pro-brain natriuretic peptide (NT-proBNP) provides prognostic information regarding the risk of death, acute heart failure and development AF in patients with coronary syndrome. While there are established cut-off values for association between clinical assessment scores in-hospital mortality, is no clear value NT-proBNP to guide stratification MI (AMI). Our study sought evaluate all-cause mortality post AMI compare other available scores. Methods: We conducted a...
There are an increasing number of reports myocarditis associated with mRNA-based COVID-19 vaccination. We describe the case a female patient underlying systemic lupus erythematosus, who developed heart failure symptoms following second dose BNT162b2 vaccine. Despite her history refractory disease remained stable after she began rituximab treatment. She underwent serial transthoracic echocardiogram and cardiac magnetic resonance imaging for evaluation cardiomyopathy. showed improvement in...
BackgroundAcute Inferior ST Elevation Myocardial Infarction (Ac-Inf-STEMI) and associated posterior right ventricular (RV) infarction has been extensively studied with electrophysiology echocardiography.A recent CMR study showed that poor RV function was long term survival post myocardial infarction.However, limited data exists especially on short clinical outcomes in Ac-Inf-STEMI. ObjectivesDetermining the RVEF, atrial ejection fraction (RAEF), other characteristics Ac-Inf-STEMI association...
Abstract Funding Acknowledgements Type of funding sources: Private company. Main source(s): Novartis Corporation Sdn Bhd Background Heart failure is a debilitating disease associated with multiple comorbidities and poor prognosis. Dyslipidemia, the top 5 most common comorbidities, including HF patients. Nonetheless, lipid profiles in population scarcely available poorly understood. Purpose This report aimed to describe in-hospital outcome hospitalized Methods MYHF registry prospective,...