- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Global Public Health Policies and Epidemiology
- Cardiac Arrest and Resuscitation
- Electrolyte and hormonal disorders
- Blood Pressure and Hypertension Studies
- Chronic Disease Management Strategies
- Cardiac Valve Diseases and Treatments
- Attention Deficit Hyperactivity Disorder
- Potassium and Related Disorders
- Congenital Heart Disease Studies
- COVID-19 Impact on Reproduction
- Vaccine Coverage and Hesitancy
- Genetic Associations and Epidemiology
- Hemodynamic Monitoring and Therapy
- Lipoproteins and Cardiovascular Health
- Acute Kidney Injury Research
- Ion channel regulation and function
- Coronary Interventions and Diagnostics
- Cardiovascular Health and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
Ministry of Health
2020-2025
Hospital Kuala Lumpur
2017-2025
Child Development Center
1980
Background: The use of urinary sodium to guide diuretics in acute heart failure is recommended by experts and the most recent European Society Cardiology guidelines. However, there are limited data support this recommendation. ENACT-HF study (Efficacy a Standardized Diuretic Protocol Acute Heart Failure) investigated feasibility efficacy standardized natriuresis-guided diuretic protocol patients with signs volume overload. Methods: was an international, multicenter, open-label, pragmatic,...
Background: Three main phenotypes describe heart failure (HF) according to left ventricular ejection fraction (LVEF). This study aims the characteristics, management and outcomes of hospitalised patients with HF categorised by LVEF. Methods: The Malaysian National Heart Failure (MY-HF) Registry is a 3-year prospective, observational admitted for acute HF. analysis includes 2,651 into: reduced (HFrEF; LVEF ≤40%), mildly (HFmrEF; 41−49%) preserved (HFpEF; ≥50%). Hospital readmission mortality...
Although acute heart failure (AHF) with volume overload is treated loop diuretics, their dosing and type of administration are mainly based upon expert opinion. A recent position paper from the Heart Failure Association (HFA) proposed a step-wise pharmacologic diuretic strategy to increase response achieve rapid decongestion. However, no study has evaluated this protocol prospectively.
Abstract Aims Heart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Failure (MY‐HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of identify areas for improvement within national services. Methods results MY‐HF 3‐year prospective, observational study comprising 2717 admitted acute HF. We report description baseline at admission outcomes index hospitalization these patients. mean...
Bleeding outcomes are crucial primary safety endpoints in studies involving thrombolytic agents. This study aimed to determine the incidence, characteristics and mortality of bleeding following ST-elevation myocardial infarction (STEMI) thrombolysis an Asian population.
Although the burden of premature myocardial infarction (MI) is high in Malaysia, direct evidence on determinants MI this multi-ethnic population remains sparse.The Malaysian Acute Vascular Events Risk (MAVERIK) study a retrospective case-control established to investigate genomic, lipid-related, and other acute Malaysia. In paper, we report protocol early results.By June 2019, had enrolled approximately 2500 patients with their first controls without cardiovascular disease, who were...
Three-factor Prothrombin Complex Concentrate (3F-PCC) containing factors II, IX and X was introduced to Malaysian public hospitals for warfarin reversal since 2017. Local studies on the outcomes of 3F-PCC use are limited. This study aimed determine extent target international normalized ratio (INR) achievement adverse drug reactions (ADRs) associated with in reversal. retrospective cohort analyzed data from adult patients who received anticoagulation between September 2017 January 2020....
Abstract Funding Acknowledgements Type of funding sources: Private company. Main source(s): Novartis Corporation Sdn Bhd Background In real world settings, factors that may affect prognosis HF patients include comorbidities, lack guideline-directed medical therapies (GDMT) and laboratory findings in particular elevated cardiac biomarkers. Purpose This report aimed to provide insights into these important clinical characteristics hospitalized patients. Methods MYHF registry is a prospective,...
Abstract Funding Acknowledgements Type of funding sources: Private company. Main source(s): Novartis Corporation Sdn Bhd Background Heart failure is a debilitating disease associated with multiple comorbidities and poor prognosis. Dyslipidemia, the top 5 most common comorbidities, including HF patients. Nonetheless, lipid profiles in population scarcely available poorly understood. Purpose This report aimed to describe in-hospital outcome hospitalized Methods MYHF registry prospective,...
Category: Research in AKI (Basic, translational, clinical including trials) Presenter: Dr MIN HUI TAN Keywords: Acute kidney injury, coronary care unit, prevalence, aetiology
Category: Research in AKI (Basic, translational, clinical including trials) Presenter: Dr MIN HUI TAN Keywords: heart failure, worsening renal function
Introduction: There is scarcity of big data on Heart Failure (HF) in the Asean region current era guideline directed medical therapy (GDMT). Malaysia (MYHF) Registry was set up 2019 to advance fundamental understanding burden, morbidity and mortality among Malaysian patients with HF Objective: This analysis determine baseline characteristics, diagnostic work treatment pattern admitted diagnosis address unmet growing clinical needs Malaysia. Methods: The first ever National planned as a...