H.A. Zainal

ORCID: 0000-0001-9707-0846
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Advanced MRI Techniques and Applications
  • Cardiomyopathy and Myosin Studies
  • Infective Endocarditis Diagnosis and Management
  • Lipoproteins and Cardiovascular Health
  • HIV-related health complications and treatments
  • Acute Myocardial Infarction Research
  • Cardiovascular Effects of Exercise
  • Viral Infections and Immunology Research
  • Cardiovascular Disease and Adiposity
  • Sports Performance and Training
  • Atrial Fibrillation Management and Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Health and Disease Prevention
  • Cardiac Arrhythmias and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiac pacing and defibrillation studies
  • Kawasaki Disease and Coronary Complications
  • Hemodynamic Monitoring and Therapy
  • Pulmonary Hypertension Research and Treatments
  • Diphtheria, Corynebacterium, and Tetanus
  • Actinomycetales infections and treatment
  • Biomarkers in Disease Mechanisms
  • Cancer, Lipids, and Metabolism

Universiti Teknologi MARA
2016-2025

Goethe University Frankfurt
2018-2024

Hospital Sungai Buloh
2019-2023

University Hospital Frankfurt
2018-2021

German Centre for Cardiovascular Research
2021

Kardiologie Frankfurt-Sachsenhausen
2021

Cardiovascular Center Frankfurt
2019

Left atrial (LA) strain is a prognostic biomarker with utility across spectrum of acute and chronic cardiovascular pathologies. There are limited data on intervendor differences no intermodality for LA strain. We sought to compare the between transthoracic echocardiography (TTE) cardiac magnetic resonance (CMR) derived hypothesized that various components would show good correlation but there be systematic vendors modalities.We evaluated 54 subjects (43 patients clinical indication CMR 11...

10.1093/ehjci/jez303 article EN European Heart Journal - Cardiovascular Imaging 2019-11-18

Profound left ventricular (LV) hypertrophy with diastolic dysfunction and heart failure is the cardinal manifestation of remodelling in chronic kidney disease (CKD). Previous studies related increased T1 mapping values CKD diffuse fibrosis. Native a non-specific readout that may also relate to intramyocardial fluid. We examined concomitant T2 signatures undertook comparisons other hypertrophic conditions.In this prospective multicentre study, consecutive patients (n = 154) undergoing routine...

10.1016/j.ijcard.2020.03.002 article EN cc-by-nc-nd International Journal of Cardiology 2020-03-03

The goal of this study was to examine prognostic relationships between cardiac imaging measures and cardiovascular outcome in people living with human immunodeficiency virus (HIV) (PLWH) on highly active antiretroviral therapy (HAART). PLWH have a higher prevalence disease heart failure (HF) compared the noninfected population. pathophysiological drivers myocardial dysfunction worse HIV remain poorly understood. This prospective observational longitudinal included consecutive long-term HAART...

10.1016/j.jcmg.2021.01.042 article EN cc-by-nc-nd JACC. Cardiovascular imaging 2021-04-15

Background: Three main phenotypes describe heart failure (HF) according to left ventricular ejection fraction (LVEF). This study aims the characteristics, management and outcomes of hospitalised patients with HF categorised by LVEF. Methods: The Malaysian National Heart Failure (MY-HF) Registry is a 3-year prospective, observational admitted for acute HF. analysis includes 2,651 into: reduced (HFrEF; LVEF ≤40%), mildly (HFmrEF; 41−49%) preserved (HFpEF; ≥50%). Hospital readmission mortality...

10.15420/japsc.2024.42 article EN cc-by-nc Journal of Asian Pacific Society of Cardiology 2025-02-28

High sensitivity cardiac troponin T (hs-cTnT) and NT-pro-brain natriuretic peptide (NT-pro BNP) are often elevated in chronic kidney disease (CKD) associated with both cardiovascular remodeling outcome. Relationship between these biomarkers quantitative imaging measures of myocardial fibrosis edema by T1 T2 mapping remains unknown. Consecutive patients established CKD estimated glomerular filtration rate (eGFR) < 59 ml/min/1.73 m2 (n = 276) were compared to age/sex matched eGFR ≥ 60 242)...

10.1186/s12968-021-00762-z article EN cc-by Journal of Cardiovascular Magnetic Resonance 2021-03-01

<h3>Background and aim</h3> Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. The REDISCOVER (<i>Re</i>spon<i>d</i>ing to <i>I</i>ncrea<i>s</i>ing <i>C</i>ardi<i>ov</i>ascular dis<i>e</i>ase p<i>r</i>evalence) study an observational longitudinal community-based that tracks changing lifestyles, risk factors chronic disease urban rural areas of Malaysia. In this study, we aim prevalence AF its associated factors. <h3>Methods</h3> was...

10.1136/heartasia-2016-010775 article EN Heart Asia 2016-11-01

Patients with chronic kidney disease (CKD) have considerable cardiovascular morbidity and mortality. Aortic stiffness is an independent predictor of risk related to left ventricular remodeling heart failure. Myocardial fibrosis the pathophysiological hallmark failing heart. An observational study consecutive CKD patients (n = 276) undergoing comprehensive clinical magnetic resonance imaging. The relationship between aortic stiffness, myocardial fibrosis, severity was examined. Compared...

10.1016/j.ijcha.2019.100389 article EN cc-by-nc-nd IJC Heart & Vasculature 2019-06-26

Troponin elevation in myocardial injury are a common findings hospitalised COVID-19 patient. Biochemistry detection of the changes due to underlying various pathological process. The subclassification process require supplemental investigation particularly with cardiovascular magnetic resonance. Late gadolinium enhancement and parametric mapping offer excellent virtual tissue characterization following insult histological correlation. understanding where biochemistry cardiac imaging cross...

10.1159/000530717 article EN Cardiology 2023-01-01

Myocardial inflammation is increasingly detected noninvasively by tissue mapping with cardiovascular magnetic resonance (CMR). Intraindividual agreement endomyocardial biopsy (EMB) or markers of myocardial injury, high-sensitive cardiac troponin (hs-cTnT) in patients clinically suspected viral myocarditis incompletely understood.

10.1016/j.jocmr.2024.101087 article EN cc-by-nc-nd Journal of Cardiovascular Magnetic Resonance 2024-01-01

<h3>ABSTRACT</h3> We present a rare case of delayed diagnosis mitral stenosis, initially presenting with hoarseness in her voice due to left recurrent laryngeal nerve (LRLN) compression. A 60-year-old woman presented the otorhinolaryngology department following complaints progressive over 6-month period. There was dysphonia but no additional evidence cranial IX or X palsy on examination, subsequent flexible nasopharyngolaryngoscopy demonstrating vocal cord palsy. She referred for cardiology...

10.7861/clinmed.2020-0750 article EN Clinical Medicine 2020-11-01

Right-sided infective endocarditis (IE) is rare and often affects the tricuspid valve. We report a unique case of pulmonary valve IE in patient with predisposing congenital heart defect – ventricular septal (VSD). A 23-year old man VSD was admitted following 3 months’ history fever malaise. An initial transthoracic echocardiogram (TTE) failed to reveal any visible vegetations or mass. However, blood cultures revealed persistent methicillin-sensitive S taphylococcus aureus (MSSA)....

10.1177/2010105820930721 article EN cc-by-nc Proceedings of Singapore Healthcare 2020-06-05

Innovations in echocardiography 893Results: Analysis of a complete valve was performed less than 10 minutes.As compared to normal, FED and BD valves were characterized by progressively increased leaflet thickness (Table ).The distribution differed from that normal (Figure).When focusing on the P2 segment, main prolapsing region both valves, statistically significant thickening observed only ).Leaflet [mm] Normal P Whole Valve 1.31 (1.30-1.70)1.58 (1.37-1.81)*2.21 (1.85-2.66)*# <0.0001...

10.1093/eurheartj/ehx504.p4337 article EN European Heart Journal 2017-08-01

Dimensions, volumes, and mass / Cardiovascular magnetic resonance imaging for myocardial diseases 775 the AE with LL; Despite a significant difference in LL between devices (p<0.001),only patients >3 leads had increased association as (p=0.014).In ICDs, increase number of coils per ICD did not correlate higher risk despite increasing LL.No single coil an AE. 2 AE, but no correlation to was present.Table 1 reflects total change device parameters before after MRI scan.Table 1.Correlation...

10.1093/eurheartj/ehy563.p3700 article EN European Heart Journal 2018-08-01

Objective: There is increasing evidence that elevations in serum troponin levels stable asymptomatic patients with advanced chronic kidney disease are predictive of worse long-term cardiovascular outcomes and survival. The association between highly sensitive T (hs-TnP) early (CKD) not well established. We aimed to study the presence elevated hs-TnP stage 2 CKD patients. Design method: Patients below age 55 years normal renal function were recruited. Demographic details, co-morbidity, risk...

10.1097/01.hjh.0000570276.32502.c7 article EN Journal of Hypertension 2019-06-22

Abstract Introduction Increase in native T1 mapping values provides insight into presence of disease and its evolution. Despite the surge evidence, immediate clinical application these techniques is complicated by several variants sequences, whose diagnostic bioequivalence not known. Methods We undertook an intra-individual comparison two measurements based on modified Look-Locker (MOLLI) schemes, MOLLI 3(2)3(2)5 (flip angle, FA 50°, T1-FFM) 5(3)3 (FA 35°, Long) 30 patients with myocarditis...

10.1093/eurheartj/ehz746.0248 article EN European Heart Journal 2019-10-01
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