A5048609550- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Potassium and Related Disorders
- Diabetes Treatment and Management
- Cardiovascular Issues in Pregnancy
- Pericarditis and Cardiac Tamponade
- Cardiac Health and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Practices and Patient Outcomes
- Electrolyte and hormonal disorders
- Pleural and Pulmonary Diseases
- Cardiac Imaging and Diagnostics
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiovascular and Diving-Related Complications
- Cardiovascular Health and Risk Factors
- Hemoglobinopathies and Related Disorders
- Advanced Glycation End Products research
- Infective Endocarditis Diagnosis and Management
- Digital Mental Health Interventions
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cancer Treatment and Pharmacology
National Heart Institute
2011-2025
Hospital Sungai Buloh
2023
Universiti Teknologi MARA
2023
Instituto de Salud Carlos III
2021
Centro de Investigación Biomédica en Red
2021
Centro de Investigación en Red en Enfermedades Cardiovasculares
2021
Background: The use of urinary sodium to guide diuretics in acute heart failure is recommended by experts and the most recent European Society Cardiology guidelines. However, there are limited data support this recommendation. ENACT-HF study (Efficacy a Standardized Diuretic Protocol Acute Heart Failure) investigated feasibility efficacy standardized natriuresis-guided diuretic protocol patients with signs volume overload. Methods: was an international, multicenter, open-label, pragmatic,...
Background: Three main phenotypes describe heart failure (HF) according to left ventricular ejection fraction (LVEF). This study aims the characteristics, management and outcomes of hospitalised patients with HF categorised by LVEF. Methods: The Malaysian National Heart Failure (MY-HF) Registry is a 3-year prospective, observational admitted for acute HF. analysis includes 2,651 into: reduced (HFrEF; LVEF ≤40%), mildly (HFmrEF; 41−49%) preserved (HFpEF; ≥50%). Hospital readmission mortality...
Although acute heart failure (AHF) with volume overload is treated loop diuretics, their dosing and type of administration are mainly based upon expert opinion. A recent position paper from the Heart Failure Association (HFA) proposed a step-wise pharmacologic diuretic strategy to increase response achieve rapid decongestion. However, no study has evaluated this protocol prospectively.
In the Asia-Pacific region, heart failure (HF) is associated with significant health and socioeconomic burden. Given differences in epidemiology of HF, as well availability healthcare resources between Asian Western countries, an Pacific Society Cardiology (APSC) working group developed consensus recommendations on management chronic HF region. The APSC expert panel reviewed appraised available evidence using Grading Recommendations Assessment, Development Evaluation (GRADE) system....
Identifying patients at risk of developing premature coronary artery disease (PCAD) which occurs age below 45 years old and constitutes approximately 7–10% (CAD) worldwide remains a problem. Oxidative stress has been proposed as crucial step in the early development PCAD. This study was conducted to determine oxidative status PCAD comparison CAD patients. (<45 old) (>60 were recruited with age-matched controls (n = 30, each group). DNA damage score, plasma malondialdehyde (MDA) protein...
Abstract Aims Heart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Failure (MY‐HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of identify areas for improvement within national services. Methods results MY‐HF 3‐year prospective, observational study comprising 2717 admitted acute HF. We report description baseline at admission outcomes index hospitalization these patients. mean...
Abstract Aims Heart failure (HF) affects an estimated 38 million people worldwide and is the leading cause of hospitalization among adults elderly. Evidence suggests that there may be regional ethnic differences in prevalence, outcomes management HF. The aim this study was to understand disease burden treatment patterns patients hospitalized for HF multi‐ethnic Malaysia. Methods results A retrospective, non‐interventional conducted utilizing 10 years medical records from National Institute...
Intramyocardial dissecting haematoma is a rare complication of myocardial infarction (MI) associated with high mortality rates. Studies and research this occurrence are limited largely to isolated case reports or series.We report late presenting MI, where on initial echocardiogram had what was thought be an intraventricular clot. However, upon further evaluation, the patient actually intramyocardial haematoma, supporting echocardiographic features distinguish it from typical left ventricular...
Background: There is sparsity in regional data surrounding heart failure with preserved ejection fraction (HFpEF)-related acute decompensated (ADHF) admissions southeast Asia. This study aims to describe the characteristics, clinical parameters and outcomes related HFpEF-linked ADHF admissions. Methods: A retrospective, observational was conducted a major cardiac tertiary centre Malaysia over 10-year period (2009–2018). total of 4,198 patients were identified, which 632 had HFpEF. Results:...
•Doppler interrogation in bedside POCUS practice is an essential tool.•Various echocardiographic findings exist the face of pulmonary hypertension.•McConnel’s sign, MSN, and 60/60 sign are linked to PE.