- Dental Implant Techniques and Outcomes
- Wound Healing and Treatments
- Endodontics and Root Canal Treatments
- Bone Tissue Engineering Materials
- Bone health and treatments
- Dental Radiography and Imaging
- Oral and Maxillofacial Pathology
- Periodontal Regeneration and Treatments
- Bone Tumor Diagnosis and Treatments
- Cancer Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Burn Injury Management and Outcomes
- Surgical Sutures and Adhesives
- Electrospun Nanofibers in Biomedical Applications
- Ion Channels and Receptors
- dental development and anomalies
- Quinazolinone synthesis and applications
- Head and Neck Surgical Oncology
- Vitamin C and Antioxidants Research
- Dental materials and restorations
- Laser Applications in Dentistry and Medicine
- Orthodontics and Dentofacial Orthopedics
- SARS-CoV-2 detection and testing
- Tuberculosis Research and Epidemiology
- Bone Metabolism and Diseases
Chulalongkorn University
1993-2023
Tokyo Medical and Dental University
2010-2013
Regeneration of bone requires the combination appropriate drugs and an delivery system to control cell behavior. However, multiple heal is complicated by availability carriers. The aim this study was explore a new for selective EP4 receptor agonist (EP4A) in with low-dose morphogenetic protein 2 (BMP-2).Combined EP4A BMP-2 carried out nanogel-based scaffold shape disc, repair critical-size circle-shaped defects calvariae that otherwise did not spontaneously.Combination treatment nanogel...
Vitamin C or L-ascorbic acid has diverse functions in the body, especially healing promotion tissue injury via participating hydroxylation reactions required for collagen formation. Systemic administration of vitamin plays an important role on gingival fibroblast proliferation and functions. Whether local rinsing alters wound behavior remains unclear. The aim this study was to investigate effect utilizing vitro model. Primary human fibroblasts isolated from were rinsed with medium containing...
PurposeThere are two commonly cited modulus of elasticity the human periodontal ligament (EPDL), i.e., 6.89 ✕ 10−5 GPa (E1) and 10−2 (E2), which exactly 1000-fold different from each other. This study aims to clarify ambiguity EPDL used for simulations determine a more accurate value first premolars using experimental simulation approaches.MethodsNumerical finite element analysis were performed analyze PDL deformation under an average Asian occlusal force. To confirm results, simple...
Abstract Objective The effect of different deproteinized bovine bone mineral (DBBM) particle sizes on healing in maxillary sinus floor augmentation remains unclear. This study compared the newly formed tissue and angiogenesis‐related after using large or small DBBM particles. Materials Methods Overall 32 patients were randomly divided into two groups either (1–2 mm) (0.25–1 particles for augmentation. After 6 months, mineralized volume was calculated micro‐computed tomography (micro‐CT)...
Many histologic and histomorphometric studies as well systematic reviews have shown the clinical success of use anorganic bovine bone (ABB, Bio-Oss) in maxillary sinus floor augmentation (MSFA). The molecular processes involved healing are, however, still unknown. aims this study were to explore gene expression associated with remodeling inflammation MSFA sites.The mRNA levels runt related transcription factor 2 (RUNX2), receptor activator NF-kB ligand (RANKL), osteoprotegerin (OPG), matrix...
Vitamin C is essential for wound healing. However, there are no reports concerning the effect of a different dose vitamin on extraction size clinically. Therefore, aim this study was to investigate oral doses A split-mouth, double-blind randomized clinical trial performed in 42 patients who underwent symmetric bilateral noninfected premolar extraction. The were randomly divided into 3 groups, namely, P/600, P/1,500, and 600/1,500 (14 each group); P/600: placebo vs. 600 mg C/d, P/1,500: 1,500...
A split-mouth single-blind randomized-controlled clinical trial study was designed to investigate the effect of local and systemic vitamin C administration on extraction wound healing. Thirty patients who underwent bilateral premolar were randomly divided into three group pairs; 1: control (Con/CSA), 2: a combination (Con/CLSA), 3: (CSA/CLSA). The (600 mg) taken by swallowing (systemic administration) or slow oral dissolution (combined administration). socket size radiographic density...
To investigate the role of phosphatase and tensin homolog (PTEN) in dental pulp cells (hDPs) adipose-derived mesenchymal stem (hADSCs).Genetic variant was identified with exome sequencing. The hDPs isolated from a patient Cowden syndrome were investigated for their proliferation, osteogenesis, adipogenesis, gene expression compared controls. normal hADSCs treated PTEN inhibitor, VO-OHpic trihydrate (VOT), to effect inhibition.A heterozygous nonsense variant, c.289C>T (p.Gln97*), patient's...
Osteochondroma of mandibular condyle is a rare benign tumor.This case report described clinical, radiographic features, differential diagnosis, histopathologic correlation and treatment condylar osteochondroma.Conebeam computed tomography (CBCT) an alternative modality to CT or MRI that should be performed in all cases suspected osteochondroma the condyle.
Marsupialization and decompression are treatments designed to reduce hydrostatic pressure which results in reducing the cystic size increasing bone density of lesion. To compare percentage reduction change radiographic from marsupialisation two types decompression: tube drain stent. Retrospective analysis panoramic films was conducted evaluate intralesional density. Data were analysed 40 cases, including 31 cases odontogenic cyst 9 cyst-like tumour, treated at Chulalongkorn University's...
Background A xenograft material is widely used in bone augmentation including sinus lift procedure. Commercially, Bio-Oss®, xenograft, provides small particle size (0.25–1 mm) and large (1–2 mm). However, the previous data remain unclear whether formation related different of radiographic histomorphometric study. No report demonstrates effect grafting new vascular growth after Aim/Hypothesis To compare healing neovascularization using or xenografts maxillary Material Methods Randomized,...
Potential aerosols containing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral particles can be generated during dental treatment. Hence, patient triage is essential to prevent the spread of SARS-CoV-2 in clinical settings. The present study described use rapid antigen tests for screening prior treatment an academic setting Thailand pandemic. opinions personnel toward test were also assessed. From August 25 October 3, 2021, patients who expected receive generating...