A5056820450- Hepatocellular Carcinoma Treatment and Prognosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mechanical Behavior of Composites
- Occupational and environmental lung diseases
- Structural Behavior of Reinforced Concrete
- Fiber-reinforced polymer composites
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Oral microbiology and periodontitis research
- Neuroscience and Neural Engineering
- Gastrointestinal Tumor Research and Treatment
- Salivary Gland Disorders and Functions
- Peptidase Inhibition and Analysis
- Metastasis and carcinoma case studies
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Fiber Laser Technologies
- Pleural and Pulmonary Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- thermodynamics and calorimetric analyses
- Diabetes and associated disorders
- Pancreatic and Hepatic Oncology Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Protease and Inhibitor Mechanisms
National Defense Medical College
2020-2025
Dokkyo Medical University
2024
Tokyo Medical and Dental University
2012-2022
Kudanzaka Hospital
2021-2022
National Hospital Organization
2021
Saiseikai Utsunomiya hospital
2021
Yokosuka Kyosai Hospital
2021
Monash Health
2017
Monash University
2017
Fujitsu (Japan)
2017
Abstract Glucometers are also widely used in diabetes research conducted using animal models. However, the appropriateness of measuring blood glucose levels glucometers models remains unclear. In this study, we evaluated consistency between measured by 11 and plasma a laboratory biochemical test samples collected retro-orbital sinus puncture or tail-tip amputation. both obtained those amputation, 10 yielded higher values, while 1 lower than values test, differences being direct proportion to...
Abstract Background Neutrophil extracellular traps (NETs) have been implicated in cancer progression by enhancing cell motility through the coiled-coil domain-containing protein 25 (CCDC25). Objective This study aimed to evaluate prognostic value of CCDC25 expression patients with esophageal squamous carcinoma (ESCC). Method Tissue specimens from who underwent radical esophagectomy for ESCC were analyzed investigate relationship between expression, clinicopathological features, and...
We investigated the hematologic abnormalities and prognoses in 16 cats with myelodysplastic syndromes (MDS). Nonregenerative anemia, thrombocytopenia, neutropenia were observed 15, 13, 4, respectively, of MDS. Morphologic characteristic MDS included megaloblastoid rubricytes (9 cats), hyposegmentation neutrophils (7 nuclear abnormality (10 cats) (13 micromegakaryocytes cats). Disease these was subclassified into refractory anemia (RA; 8 RA excess blasts (RAEB; 5 RAEB transformation (RAEB T;...
Studies have demonstrated that periodontal disease is associated with the development of systemic complications in patients type 2 diabetes mellitus (T2DM). The purpose this pilot study was to investigate which markers among various parameters are affected by treatment T2DM. Twelve T2DM were given oral hygiene instructions and subsequent subgingival scaling root planing. status recorded, blood urine samples taken measure glucose control at baseline 1 month following treatment. Serum...
Abstract Background Fibrotic hypersensitivity pneumonitis (HP) is a chronic interstitial lung disease caused by allergic responses to repeated exposures causative antigen. Therapeutic evidence of the use corticosteroids treat fibrotic HP remains lacking, although are recognized as major treatment option. The purpose this study was evaluate efficacy corticosteroid in patients with propensity score-matched cohort. Methods A retrospective review medical records from 2005 2019 single center...
Background Although vaccination can be a useful tool for control of avian influenza epidemics, it might engender emergence vaccine-resistant strain. Field and experimental studies show that some strains acquire resistance ability against vaccination. We investigated, in the context strain, whether program prevent spread infectious disease. also investigated how losses from immunization by imposed resistant strain affect Methods Findings designed analyzed deterministic compartment model...
Orange laser pulses were successfully generated in a Pr‐doped waterproof fluoride glass fibre (Pr:WPFGF) using graphene thin film as saturable absorber (SA). Two pulse generation modes observed: continuous mode with 0.47 µs duration 2.61 repetition period and single giant 9.7 ns duration. The peak wavelength was 603 nm. This result shows that can be effective an SA the visible region, future ultra‐short modelocking technique may demonstrated.
This paper presents a flexible thermoelectric generator (TEG) with heat path films, which efficiently convert vertical temperature difference (ΔT) into lateral ΔT for thermocouple (TC). The film consists of copper-filled-vias low thermal resistance and polymer films high resistance. They were made in two fabrication steps. first used printed circuit board density copper-filled-vias, while the second saw deposition thin TCs. combination offers flexibility application due to its thinness, mass...
Mesothelin is expressed in various types of malignant tumors. The present study immunohistochemically investigated mesothelin expression and its clinicopathological significance each subtype breast cancer, with special reference to cellular localization, particular, membrane expression. Using tissue specimens from 482 patients immunohistochemistry was used help classify localization as or cytoplasmic detected 77 (16.0%) cases the highest triple-negative cancer (31/75; 41.3%), followed by...
Aims/Introduction: Chronic inflammation aggravates glycemic control in patients with type 2 diabetes mellitus. An increase or decrease the release and activities of various inflammatory mediators, such as tumor necrosis factor (TNF)-α, interleukin (IL)-6, C-reactive protein (CRP), are presumed to be responsible for inducing insulin resistance. The purpose present study was examine effects non-surgical periodontal treatment incorporating topical antibiotics on serum mediators mellitus...
Bone development is a dynamic process that requires cell motility and morphological adaptation under the control of actin cytoskeleton. This cytoskeleton system regulated by critical modulators including actin-binding proteins. Among them, profilin1 (Pfn1) key player to fiber structure, it involved in number cellular activities such as migration. During early phase body development, skeletal stem cells osteoblastic progenitor migrate form initial rudiments for future skeletons. this...
Objectives:To determine the impact of intensity early correction hyperglycaemia on outcomes in patients with diabetic ketoacidosis (DKA) admitted to intensive care unit. Methods:We studied adult DKA 171 ICUs Australia and New Zealand from 2000 2013. We used their blood glucose levels (BGLs) fi rst 24 hours after ICU admission whether hyperglycemia ≤180 mg/dL was independently associated hypoglycaemia, hypokalaemia, hypo-osmolarity or mortality, compared partial > 180 as recommended by...
Research patients with combined lung cancer (LC) and interstitial disease (ILD) is insufficient. The objective of the study was to identify frequency such treatments, including best supportive care (BSC), in real world.All LC who were admitted our hospital over a 5-year period from 2013 2017 retrospectively analysed.In this study, 698 enrolled. A total 148 (21.2%) suffered ILD. Seventy-one LC-ILD received chemotherapy, 20 BSC only. Eleven whom physicians thought could receive therapy...
Adjuvant chemotherapy is usually not considered for pT1a pN0 human epidermal growth factor receptor 2 (HER2)‑positive breast cancer due to its low recurrence rate. The present report describes a case of hormone receptor‑positive HER2‑positive with multiple recurrences in the axillary lymph nodes and liver within 1 year after radical surgery. A 58‑year‑old woman underwent left total mastectomy sentinel node biopsy pathological stage IA (pT1a pN0). subtype corresponded luminal B‑like nuclear...
Aim: To establish a novel systemic inflammatory score (SIS) combined with neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), and C-reactive protein/albumin (CAR) to validate its prognostic value relation serum cytokine levels in patients who underwent esophagectomy for esophageal cancer (EC). Patients Methods: Preoperative NLR, PLR, CAR were evaluated 102 undergoing resection EC from 2009 2014. Receiver operating characteristic (ROC) curves censored 5-year survival plotted...