- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Respiratory Support and Mechanisms
- Allergic Rhinitis and Sensitization
- Nosocomial Infections in ICU
- Medical Malpractice and Liability Issues
- Adenosine and Purinergic Signaling
- Climate Change and Health Impacts
- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Infection Control in Healthcare
- Patient Safety and Medication Errors
- Diabetes and associated disorders
- Neonatal and fetal brain pathology
- Radiation Dose and Imaging
- Advanced battery technologies research
- Global Health and Surgery
- Palliative Care and End-of-Life Issues
- Climate variability and models
- Air Quality and Health Impacts
- Sulfur-Based Synthesis Techniques
The University of Melbourne
2022-2025
Western Health
2022-2025
Arthur B. McDonald-Canadian Astroparticle Physics Research Institute
2019
The Royal Melbourne Hospital
2017-2019
Melbourne Health
2018
Princess Alexandra Hospital NHS Trust
2014
University of Warwick
2007-2008
BackgroundA multidisciplinary collaboration investigated the world's largest, most catastrophic epidemic thunderstorm asthma event that took place in Melbourne, Australia, on Nov 21, 2016, to inform mechanisms and preventive strategies.MethodsMeteorological airborne pollen data, satellite-derived vegetation index, ambulance callouts, emergency department presentations, data hospital admissions for as well leading up following were collected between March 31, 2017, analysed. We contacted...
Abstract Adenosine is well known to be released during cerebral metabolic stress and believed neuroprotective. ATP release under similar circumstances has been much less studied. We have now used biosensors measure compare in real time the of adenosine vitro ischaemia hippocampal slices. only occurred following anoxic depolarisation, whereas was apparent almost immediately after onset ischaemia. required extracellular Ca 2+ . By contrast enhanced by removal , whilst TTX had no effect on...
After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less and vasopressor administration than FBT crystalloids. We aimed to determine whether, after reduces the duration of compared crystalloid FBT. conducted a multicentre, parallel-group, open-label, randomised clinical trial in six intensive care units (ICUs) involving surgery patients deemed require 240 receive up 400 mL albumin/day as FBT, followed by 4% for any subsequent on that day, or at least first...
Objectives:To determine the impact of intensity early correction hyperglycaemia on outcomes in patients with diabetic ketoacidosis (DKA) admitted to intensive care unit. Methods:We studied adult DKA 171 ICUs Australia and New Zealand from 2000 2013. We used their blood glucose levels (BGLs) fi rst 24 hours after ICU admission whether hyperglycemia ≤180 mg/dL was independently associated hypoglycaemia, hypokalaemia, hypo-osmolarity or mortality, compared partial > 180 as recommended by...
Objective: To investigate the environmental precipitants, treatment and outcome of critically ill patients affected by largest most lethal reported epidemic thunderstorm asthma. Design, setting participants: Retrospective multicentre observational study. Meteorological, airborne particulate pollen data, a case series 35 admitted to 15 intensive care units (ICUs) due asthma event 21–22 November 2016, in Victoria, Australia, were analysed compared with 1062 total ICU-admitted Australian 2016....
Ventilator-associated pneumonia (VAP) is the leading cause of death amongst hospital-acquired infections and also linked to an increased length stay cost care. The Institute for Healthcare Improvement ventilator bundle comprised a series interventions, which, when implemented together, have been shown decrease incidence VAP. aim this study was determine compliance if <95% [1] devise strategies improve compliance.
The report of the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) 2005 [1] provides recommendations to reduce morbidity mortality among acutely ill patients. It highlights importance for involvement consultants in referral process, clear physiological monitoring plans each patient, review by a consultant intensivist within 12 hours admission critical care. objective audit was assess compliance with these recommendations, ensuring safe management unwell patients...
Ventilator-associated pneumonia (VAP) is the leading cause of death amongst hospital-acquired infections and also linked to an increased length stay cost care. The Institute for Healthcare Improvement ventilator bundle comprised a series interventions, which, when implemented together, have been shown decrease incidence VAP. aim this study was determine compliance if <95% [1] devise strategies improve compliance.