- Pesticide and Herbicide Environmental Studies
- Effects and risks of endocrine disrupting chemicals
- Pesticide Exposure and Toxicity
- Public Health in Brazil
- Healthcare Regulation
- Patient Safety and Medication Errors
- Healthcare during COVID-19 Pandemic
- Reproductive Health and Technologies
- Diabetes and associated disorders
- Weed Control and Herbicide Applications
- Oral microbiology and periodontitis research
- Per- and polyfluoroalkyl substances research
- Pharmaceutical Practices and Patient Outcomes
- Biotin and Related Studies
- Pediatric health and respiratory diseases
- Pharmacovigilance and Adverse Drug Reactions
- Clinical Nutrition and Gastroenterology
Universidade Estadual do Oeste do Paraná
2016-2024
Abstract One of the most consumed pesticides in world is glyphosate, active ingredient herbicide ROUNDUP®. Studies demonstrate that glyphosate can act as an endocrine disruptor and exposure to this substance at critical periods developmental period may program fetus induce reproductive damage adulthood. Our hypothesis maternal during pregnancy lactation mice will affect development male organs, impairing fertility adult life. Female 0.5% glyphosate-ROUNDUP® their drinking water...
Glyphosate (GBH) is a worldwide consumption pesticide and used in the formulation of Roundup®, one most commercialized herbicides world. Maternal exposure to this herbicide can promote changes adaptations offspring; however, effects on skeletal muscle are poorly understood. In sense, present study sought evaluate effect GBH characteristics soleus (SOL) extensor digitorum longus (EDL) muscles. C57BL/6 pregnant female mice were divided into two groups: control (CTL) receiving water glyphosate...
Objective: To investigate the effect of pre and postnatal exposure to a glyphosate-based herbicide on glucose metabolism liver histology in adult F1 mice offspring. Methods: Female (C57Bl/6) received 0.5% glyphosate (Roundup Original DI®) drinking water or purified (Glyphosate Group Control respectively) during pregnancy lactation. Offspring (F1) were submitted insulin tolerance tests euthanized day 150. Body plasma parameters, analyzed. Results: Exposure [...]
Objetivo: Identificar eventos adversos a medicamentos (EAM) em pacientes adultos internados nas clínicas médica e cirúrgica um hospital universitário, bem como caracterizar esses eventos.Materiais Métodos: Foi realizado estudo retrospectivo universitário. A amostra foi constituída pelos prontuários dos entre outubro de 2010 janeiro 2011. Para identificação EAM aplicou-se conjunto rastreadores que são condições podem indicar ocorreu tornam revisão do prontuário mais objetiva direcionada....
Objective: To investigate the influence of MSG obesity and maternal periodontal disease on mandibular bone loss male offspring in adulthood.
 Methods: 60 neonatal Wistar females were used randomly separated into two groups. During first 5 days life, half female pups received subcutaneous injections cervical region monosodium glutamate (MSG), other half-received hyperosmotic saline solution (CTL). All animals experiments water standard feed. At 70 distributed four experimental groups:...
The Parenteral Nutrition (PN) is a high-alert medication, with high-cost, indicated for patients in which oral or enteral nutrition not possible, insufficient contraindicated.There are two PN systems currently available, the custom system, prepared hospital pharmacies outsourced to specialized clinics, and standardized compartmentalized bag system.Currently, it fundamental that application of financial resources health be performed efficiently, considering effectiveness, safety economy.The...
Introdução: Diabetes mellitus é uma doença crônica, considerada um problema de saúde pública mundial. O rastreamento em conjunto procedimentos que possibilita a identificação provável da facilitando diagnóstico e tratamento,pode ser realizado por vários profissionais, incluindo o farmacêutico. Objetivo: Rastrear entre os indivíduos assistidos pelo serviço Farmácia Básica no município CascavelPR, aqueles com alterações glicemia capilar ou sintomas sugestivos DM2Metodologia: Foi estudo...
Introdução: O diabetes mellitus (DM) não controlado pode provocar, a longo prazo, disfunção e falência de vários órgãos, estando associado ao aumento da mortalidade alto risco desenvolvimento complicações micro macrovasculares. Diante disso, o bom controle do DM na atenção primária evita hospitalizações maiores complicações, por isso, detecção retinopatia, nefropatia, neuropatia pé diabético deve ser realizada em tempo oportuno para acompanhamento seguimento cada paciente. Objetivo: objetivo...