- Indoor Air Quality and Microbial Exposure
- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Nanoparticles: synthesis and applications
- Field-Flow Fractionation Techniques
- Effects and risks of endocrine disrupting chemicals
- Nanoparticle-Based Drug Delivery
- Advanced Photocatalysis Techniques
- Microfluidic and Bio-sensing Technologies
- TiO2 Photocatalysis and Solar Cells
- Advanced Chemical Sensor Technologies
- Heavy metals in environment
- Noise Effects and Management
- Extraction and Separation Processes
- Coagulation and Flocculation Studies
- Microplastics and Plastic Pollution
- Smoking Behavior and Cessation
- Vehicle emissions and performance
- Extracellular vesicles in disease
- Infection Control and Ventilation
- Minerals Flotation and Separation Techniques
- Odor and Emission Control Technologies
- Toxic Organic Pollutants Impact
- Global Health and Epidemiology
- Building energy efficiency and sustainability
Joint Research Centre
2016-2025
European Commission
2006-2024
Albanian University
2012
Orszagos Kornyezetegeszsegugyi Intezet
2012
Finnish Institute for Health and Welfare
2012
Institute of Public Health
2012
Institute for Environment and Human Security
2012
E-liquids generally contain four main components: nicotine, flavours, water and carrier liquids. The liquid dissolves flavours nicotine vaporises at a certain temperature on the atomizer of e-cigarette. Propylene glycol glycerol, principal carriers used in e-liquids, undergo decomposition contact with heating-coil forming volatile carbonyls. Some these, such as formaldehyde, acetaldehyde acrolein, are concern due to their adverse impact human health when inhaled sufficient concentrations....
The implementation of the proposal from European Chemical Agency (ECHA) to restrict use nanoplastics (NP) and microplastics (MP) in consumer products will require reliable methods perform size mass-based concentration measurements. Analytical challenges arise at nanometre micrometre interface, e.g., 800 nm–10 µm, where techniques applicable scale reach their upper limit applicability approaches must be pushed lower limits detection. Herein, we compared performances nine analytical by...
Electronic cigarettes have achieved growing popularity since their introduction onto the European market. They are promoted by manufacturers as healthier alternatives to tobacco cigarettes, however debate among scientists and public health experts about possible impact on indoor air quality means further research into product is required ensure decisions of policymakers, care providers consumers based sound science. This study investigated characterised 'vaping' (using electronic cigarettes)...
The measurement of physicochemical properties polydisperse complex biological samples, for example, extracellular vesicles, is critical to assess their quality, resulting from production and isolation methods. community gradually becoming aware the need combine multiple orthogonal techniques perform a robust characterization samples. Three pillars quality attribute EVs are sizing, concentration phenotyping. repeatable vesicle one key-challenges that requires further efforts, in order obtain...
A comprehensive physicochemical characterization of heterogeneous nanoplastic (NPL) samples remains an analytical challenge requiring a combination orthogonal measurement techniques to improve the accuracy and robustness results. Here, batch methods, including dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), tunable resistive pulse sensing (TRPS), transmission electron microscopy (TEM), scanning (SEM), as well separation/fractionation methods such centrifugal liquid...
AF4-ICP-MS for determination of size distribution silver nanoparticles.
Single particle-inductively coupled plasma mass spectrometry (SP-ICPMS) is a promising technique able to generate the number based-particle size distribution (PSD) of nanoparticles (NPs) in aqueous suspensions. However, SP-ICPMS analysis not consolidated as routine-technique yet and typically applied real test samples with unknown composition. This work presents methodology detect, quantify characterise number-based PSD Ag-NPs different environmental (drinking lake waters), derived from...
Analytical ultracentrifugation (AUC) is a powerful tool for the study of particle size distributions and interactions with high accuracy resolution. In this work, we show how analysis sedimentation velocity data from AUC can be used to characterize nanocarrier drug delivery systems in nanomedicine. Nanocarrier distribution ratio free versus nanoparticle-encapsulated commercially available liposomal doxorubicin formulation are determined using interference absorbance based measurements...
Titanium dioxide is a white colourant authorised as food additive E171 in the EU and applied range of products. Currently specifications for do not refer to characterisation particle size distribution; however, this may be requested near future. Only few studies have been published date reporting data on distribution grade titanium dioxide. The aim study was characterise particles contained eight confectionery products pristine samples used each This allowed direct comparison both extracted...
Titanium dioxide is a white colourant authorised as food additive E 171 in the EU, where it used range of alimentary products. As these materials may contain fraction particulates with sizes below 100 nm and current EU regulation requires specific labelling ingredient to indicate presence engineered nanomaterials there now need for standardised validated methods appropriately size quantify (nano)particles matrices. A single-particle inductively coupled plasma mass spectrometry (spICP-MS)...
The use of face masks is among the measures taken to prevent person-to-person transmission virus (SARS-CoV-2) responsible for coronavirus disease (COVID-19). Lately, concern was expressed about possibility that carbon dioxide could build up in mask over time, causing medical issues related respiratory system. In this study, concentration breathing zone measured while wearing a surgical mask, KN95 and cloth mask. For determined under different conditions (office work, slow walking, fast...
In single particle inductively coupled plasma mass spectrometry (spICP-MS), the transport efficiency is fundamental for correct determination of both number concentration and size. present study, was systematically determined on three different days with six carefully characterised gold nanoparticle (AuNP) suspensions in seven European US expert laboratories using ICP-MS instruments spICP-MS software. Both size-(TES)-and frequency-(TEF)-methods were applied. The resulting efficiencies did...
This work proposes the use of multimodal mixtures monodispersed silica nanoparticles (SiO2–NPs) standards for simultaneous determination size and concentration SiO2–NPs in aqueous suspensions by asymmetric flow field-flow fractionation (AF4) coupled to inductively plasma mass spectrometry (ICPMS). For such a purpose, 20, 40, 60, 80, 100, 150 nm were characterized transmission electronic microscopy (TEM), centrifugal liquid sedimentation (CLS), dynamic light scattering (DLS) measuring...
Synthetic amorphous silica (SAS) has been used as food additive under the code E551 for decades and agrifood sector is considered a main exposure vector humans environment. However, there still lack of detailed methodologies determination SAS' particle size concentration. This work presents detection characterization NPs in eleven different food-grade SAS samples, following reasoned sequential methodology. Dynamic Light Scattering (DLS), Multiangle (MALS), Asymmetric Flow-Field Flow...
Previous experimental and epidemiologic studies suggested that exposure to ultrafine particles (UFP) may result in adverse health effects. Metrics such as the number-concentration especially surface-area or lung-deposited surface area (LDSA) appear be appropriate metrics of dose for predicting pulmonary inflammation insoluble poorly soluble particles. Currently not much data including LDSA concentrations is available. The aim this study was therefore measure a variety occupational...
Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, highliting urgent need for new therapeutic strategies. Peptide-based therapies have demonstrated significant potential treating CVDs; however, their clinical application is hindered by limited stability in physiological fluids. To overcome this challenge, an effective drug delivery system essential to protect and efficiently transport peptides intended targets. This study introduces two distinct strategies...
A growing number of studies indicate the significance short-term exposures to airborne particulate matter, such as those occurring in a vehicle cabin. In this study, PM10, PM2.5, PM1 concentrations were measured using optical particle counters eighteen tobacco smoke-free private cars movement. The average 48.6 µg/m3, 26.9 µg/m3 and 22.6 for PM2.5 PM1, respectively. These levels found depend directly on ambient air PM concentration choice ventilation used inside cars. particles with diameter...
Polycyclic Aromatic Hydrocarbons (PAHs) have been detected in rubber and plastic components of a number consumer products such as toys, tools for domestic use, sports equipment, footwear, with carbon black extender oils having identified principal sources. In response to these findings, the European Union Regulation (EU) No. 1272/2013 was adopted December 2013, amending entry 50 Annex XVII Registration, Evaluation, Authorisation, Restriction Chemicals (REACH) directive establishing...