A5024624391- Advanced Proteomics Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Selenium in Biological Systems
- Trace Elements in Health
- Advanced biosensing and bioanalysis techniques
- Mercury impact and mitigation studies
- Dye analysis and toxicity
- Analytical chemistry methods development
- Bone health and treatments
- Heavy Metal Exposure and Toxicity
- Proteins in Food Systems
- Environmental Toxicology and Ecotoxicology
- Occupational exposure and asthma
- Metabolomics and Mass Spectrometry Studies
- Identification and Quantification in Food
- Aquaculture Nutrition and Growth
- Nutritional Studies and Diet
- Contact Dermatitis and Allergies
- Chemical Safety and Risk Management
- Per- and polyfluoroalkyl substances research
- Spectroscopy and Chemometric Analyses
- Diverse academic and cultural studies
- Oral microbiology and periodontitis research
- Polymer Surface Interaction Studies
- Heavy Metals in Plants
Istituto Superiore di Sanità
2020-2023
Sapienza University of Rome
2016-2018
In single particle inductively coupled plasma mass spectrometry (spICP-MS), the transport efficiency is fundamental for correct determination of both number concentration and size. present study, was systematically determined on three different days with six carefully characterised gold nanoparticle (AuNP) suspensions in seven European US expert laboratories using ICP-MS instruments spICP-MS software. Both size-(TES)-and frequency-(TEF)-methods were applied. The resulting efficiencies did...
Graphitized carbon black (GCB) has been employed for extraction of several classes analytes, due to the large surface area and unique chemistry its groups that allows extracting a wide range including polar, acidic compounds. Despite fact structurally related materials, such as graphene, found application hybrid-components in phosphoproteomics, surprisingly, GCB never used selective enrichment phosphopeptides. For this purpose, present work we prepare magnetic composite with TiO2 (mGCB@TiO2)...
In the present study, we addressed knowledge gaps regarding agglomeration behavior and fate of food-grade titanium dioxide (E 171) in human gastrointestinal digestion (GID). After thorough multi-technique physicochemical characterization including TEM, single-particle ICP-MS (spICP-MS), CLS, VSSA determination ELS, GI E 171 was studied by applying vitro GID approach established for regulatory risk assessment nanomaterials Europe, using a standardized international protocol. investigated...
Nanocellulose (NC) is an emerging material in the food sector with several prospective application areas. Three main types of NC exist, i.e. bacterial (BNC), nanofibrillated cellulose (NFC), and nanocrystals (CNC). The biological sources processing conditions affect physicochemical parameters NC. In present project, a NAM-based IATA for addressing data gaps assessment potential hazards associated to oral exposure was considered. This focused on three pillars, (i) uptake crossing intestinal...
Blue whiting (Micromesistius poutassou), pouting (Trisopterus luscus) and common dab (Limanda limanda) are underutilized fish species attractive in terms of sustainability. However, there is limited information about their nutritional characteristics as well potential presence environmental contaminants. Specimens caught European waters were characterised for content essential toxic elements. The three species, along with carp blue mussels, relevant sustainable production too, employed raw...
A method was developed for the determination of total titanium in food and supplements by inductively coupled plasma mass spectrometry (ICP-MS) after microwave-assisted acid digestion samples. Five supplements, including one certified reference material, 15 products were used development. Key factors affecting analytical results, such as composition mixture sample bias from spectral interferences on different isotopes, investigated. Resolution achieved ICP-MS/MS with ammonia adduct formation...
Liquid chromatography coupled to high‐resolution mass spectrometry is the technique of choice for untargeted profiling food matrices. Despite high potential spectrometry, when dealing with complex mixtures, an efficient separation also needed. The novel core‐shell chromatographic columns packed sub‐2 μm sized particles are claimed show very good resolution. However, analytes retention can be significantly altered working under ultra‐high performance conditions. In this work, evaluation four...
Selenium (Se) is an essential trace element required for normal development as well to counteract the adverse effects of environmental stressors. Conditions low Se intake are present in some European countries. Our aim was investigate short- and long-term early-life supply on behavior synaptic plasticity with a focus hippocampus, considering both suboptimal per se its interaction developmental exposure lead (Pb). We established animal model restriction Pb exposure; female rats fed optimal...
Biofortification is a promising strategy to improve the nutrient profile of farmed fish but requires consideration bioaccessible fraction. In this study, in vitro bioaccessibility macro and trace elements was investigated biofortified conventional gilthead seabream common carp, also taking into account effect cooking (by steaming). enhanced iodine selenium levels carp fillets. Steaming increased contents seabream, decreased copper carp. Higher bioaccessibilty (> 80%) observed compared (45%)....