A5100355391- Blood Pressure and Hypertension Studies
- Neurological Disease Mechanisms and Treatments
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Cancer-related molecular mechanisms research
- Atrial Fibrillation Management and Outcomes
- Pressure Ulcer Prevention and Management
- Hormonal Regulation and Hypertension
- Pharmacological Effects of Natural Compounds
- Neurological Disorders and Treatments
- RNA regulation and disease
- Mitochondrial Function and Pathology
- Ergonomics and Musculoskeletal Disorders
- Airway Management and Intubation Techniques
- Advanced Glycation End Products research
- Autophagy in Disease and Therapy
- Boron Compounds in Chemistry
- MicroRNA in disease regulation
- Meta-analysis and systematic reviews
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Acupuncture Treatment Research Studies
- Enhanced Recovery After Surgery
- Cardiac Fibrosis and Remodeling
PLA 306 Hospital
2024
Third Xiangya Hospital
2019-2024
Central South University
2015-2024
First Affiliated Hospital of Xi'an Jiaotong University
2017-2023
Southern Medical University
2023
Xiangya Hospital Central South University
2004-2015
Southwest Medical University
2006-2013
First Affiliated Hospital of Sichuan Medical University
2006-2013
Shanghai University of Traditional Chinese Medicine
2002
Recent studies have revealed that circular RNAs (circRNAs) play important roles in the tumorigenesis of human cancer, including hepatocellular carcinoma (HCC). In present study, we screen RNA expression profiles HCC tissue and investigate molecular on tumorigenesis. Human circRNA microarray analysis showed there were total 1,245 differently expressed RNAs, 756 up-regulated circRNAs 489 down-regulated circRNAs, three pairs adjacent normal tissue. Hsa_circ_0016788 was identified to be both...
Background . Gastrointestinal functional recovery is an important factor affecting postoperative outcome. The aim of this study was to evaluate the effect transcutaneous electrical acupoint stimulation (TEAS) on gastrointestinal function in women undergoing cesarean section. Methods 150 pregnant section were randomly allocated into TEAS, nonacupoint (sham group), and no (control group). primary outcome indications secondary outcomes included time first mobilization, hospital stay, daily...
Aim: Sevoflurane could induce apoptosis of rat hippocampal neurons, while theaflavins (TFs) have antioxidant and anti-inflammatory properties. This study aims to explore whether TFs alleviate sevoflurane-induced neuronal cell injury.Materials methods: Cells were treated by concentration gradient sevoflurane TFs. Cell viability, level reactive oxygen species (ROS) rate determined counting kit-8 (CCK-8) flow cytometry, respectively. Quantitative PCR (qPCR) western blot performed determine mRNA...
In comparison with the most preferred genetic marker utilized in forensic science (STR), insertion/deletion analysis possesses further benefits, like absence of stutter peak, low mutation rate, and enabling mixed stain analysis. At present, a total 169 unrelated healthy Dongxiang individuals dwelling Autonomous county Gansu province were recruited our study to appraise usefulness panel including 30 autosomal diallelic markers. The insertion allele frequencies range 0.1598 at HLD 111 0.8550...
Vortioxetine is a novel antidepressant approved for the treatment of major depressive disorder by US Food and Drug Administration in September 2013. This meta-analysis assessed efficacy safety different doses vortioxetine generalized anxiety adults.PubMed, Cochrane Library, PsycINFO, Clinical Trials databases were searched from 2000 through 2015. The abstracts annual meetings American Psychiatric Association previous reviews to identify additional studies. search was limited individual...
Abstract Background Combined antihypertensive therapy has obvious advantages over single drug therapy. Hypertension guidelines fully affirm the efficacy of dual combination in initial Recent studies have also pointed out that quadruple very low-dose drugs is superior to drugs. However, whether better than unknown. Methods/design A randomized double-blind crossover clinical trial will be conducted compare and safety antihypertensives (irbesartan 75 mg + metoprolol 23.75 amlodipine 2.5...
To investigate the anxiety status of infertile patients and influential factors. A questionnaire survey was performed in 306 patients, who were consulted Xiangya Hospital, Central South University, Productive Genetic Hospital CITIC-Xiangya from June, 2013 to 2014. self-designed general information on due infertility used investigation. The incidence for participants 61.4%. single factor analysis showed that some about including ages, marriage age, duration infertility, number reproductive...
Abstract In this paper, we generated a short hairpin RNA growth differentiation factor‐11 (sh‐GDF11) and evaluated the effects of sh‐GDF11 on pathogenesis acute liver failure (ALF) in vitro vivo. Through bioinformatics study, key gene related to ALF was assayed. Lipopolysaccharide (LPS) D‐galactoamine (D‐GalN) were applied establish mouse model LPS/D‐GalN‐induced injury, TNF‐α D‐Gal used construct an cell model, followed by treatment for analysis proliferation. Bioinformatics showed that...
Tracheal stenosis may occur secondary to trauma, tumors, infections, and inflammatory iatrogenic diseases. Patients with tracheal must be evaluated carefully require comprehensive preoperative examination, including pulmonary function tests radiographic studies. Two male patients (one 18 years of age the other 46 age) were scheduled for resection reconstruction. They given different modes anesthesia (with without intubation). Fiberoptic intubation was selected in 18-year patient,...
To evaluate the accuracy and stability of arterial blood gas (ABG) results by comparison with venous measurements from routine tests, to compare performance two sampling syringes, pre-heparinized syringe (PHS) disposable (DABS), in ABG analysis.We retrospectively analyzed practical use PHS DABS collecting samples, involving 500 400 patients, respectively. For each patient, addition sample, a sample was also collected using collection tube (VBCT) used for tests. Accordingly, patients were...
To investigate the effects of ginsenoside Rb1 on high glucose-induced neurotoxicity and underlying molecular mechanism in primary cultured Schwann cells (SCs).Cultured SCs were divided into six groups that received (a) normal glucose, (b) osmotic control, (c) (d) glucose plus 1 μM Rb1, (e) 10 or (f) 100 alpha lipoic acid (ALA). Intracellular reactive oxygen species (ROS) generation mitochondrial transmembrane potential (ΔΨm) detected by flow cytometric analyses. Apoptosis was confirmed...
The study's goals are to fabricate PLGA nanoparticles (PNPs) loaded with apigenin (AP) and adenosine (AD) using a microfluidic preparation method standard emulsification investigate the possible heart-protective effects of AP-AD PNPs made method. Compared microfluidics, fabricated small-size nanoparticles, which better at encapsulating drugs, retaining more having low viscosity for myocardial infarction (MI) injection. TheMI model was developed SD rats injected under skin 85 mg/kg...
Background. Salvianolic acid B (Sal B) is a bioactive component of Radix Salviae, which has antiinflammation and antiapoptotic activity in diabetic complications. However, the molecular mechanism action Sal on peripheral neuropathy (DPN) unknown. This study was designed to identify for treatment DPN by using pharmacology network, docking, vitro experiments. Methods. DPN-related targets from Gene Cards OMIM platforms were retrieved screened. Then, an analysis possible with STRING Cytoscape...