A5074437100- CAR-T cell therapy research
- Drug-Induced Adverse Reactions
- Monoclonal and Polyclonal Antibodies Research
- Platelet Disorders and Treatments
- Immune Cell Function and Interaction
- Systemic Lupus Erythematosus Research
- Erythropoietin and Anemia Treatment
- Immunotherapy and Immune Responses
- Hematopoietic Stem Cell Transplantation
- Contact Dermatitis and Allergies
- Systemic Sclerosis and Related Diseases
- Immunodeficiency and Autoimmune Disorders
- Cancer Cells and Metastasis
- Pharmacovigilance and Adverse Drug Reactions
- Cancer Immunotherapy and Biomarkers
- PARP inhibition in cancer therapy
- Herpesvirus Infections and Treatments
- Viral Infectious Diseases and Gene Expression in Insects
- Cancer, Hypoxia, and Metabolism
- Advanced Proteomics Techniques and Applications
- Metabolism and Genetic Disorders
- Polyomavirus and related diseases
- Urticaria and Related Conditions
- Blood groups and transfusion
- Asthma and respiratory diseases
Bicêtre Hospital
2020-2025
Assistance Publique – Hôpitaux de Paris
2020-2025
Unité de Technologies Chimiques et Biologiques pour la Santé
2020-2025
Université Paris Cité
2014-2025
Inserm
2020-2025
Centre National de la Recherche Scientifique
2020-2025
Sorbonne Université
2017-2020
Hôpital Tenon
2019-2020
Pitié-Salpêtrière Hospital
2017
Hôpital Saint-Louis
2014
A number of drug treatments are known to alter the dialogue between gut microbiota and immune system components in digestive mucosa. Alterations intestinal homeostasis now well affect peripheral responses favor occurrence a pathologies such as allergies cancers. Erythropoietin’s pleiotropic effects might explain adverse events sometimes observed anemic patients treated by erythropoiesis-stimulating agents (ESA). However, impact this therapeutic cytokine on tract has not previously been...
Abstract The adverse effects observed in some cancer patients treated with erythropoiesis‐stimulating agents such as erythropoietin (EPO) might be due to the latter's well‐known immunosuppressive functions. Here, we used a mouse model of syngeneic triple‐negative breast explore EPO's immunomodulatory role tumour setting. Our results showed that EPO treatment promotes growth, exacerbates ‘immune desert’, and ‘cold tumour’. changed immune cell distribution peripheral blood, secondary lymphoid...
Activating anti-angiotensin type 1 receptor antibodies (AT1R-AA) have been described in patients with systemic scleroderma, an auto-immune disorder clinical fibrotic features. Chronic graft-versus-host disease (cGvHD) after hematopoietic stem cell transplantation may features, whose pathogenesis be similar sclerosis.To evaluate the presence of AT1R-AA and their association biological symptoms cGvHD patients.Sera from 87 including 45 extensive 42 without were retrospectively analyzed for...
Abstract Objectives Given that method validation is mandatory for compliance with the International Organization Standardization (ISO) 15,189 standard requirements, we evaluated analytical performance of AQUIOS CL system (Beckman Coulter) and compared it two bead-based flow cytometry (FCM) protocols (BD FACSCAnto TM- II Beckman Coulter DxFLEX). There are no comparative literature data on standardized counting lymphocyte subsets new-generation cytometer DxFLEX. Methods We CL’s regard to...
Background: Multiple sclerosis (MS) may occur before the age of 18. Differentiation between paediatric MS (PedMS) and other demyelinating syndromes (ODSs) is challenging. In adult with MS, kappa free light chain (KFLC) index has proven to be a reliable marker intrathecal Ig synthesis. Objective: To assess diagnostic value KFLC in cohort patients paediatric-onset, inflammatory disorders CNS. Methods: We included 73 divided them into four groups: PedMS ( n = 16), ODS 17), encephalitis and/or...
In both immediate (IHS) and delayed hypersensitivity reactions (DHS) cross-reactivity between penicillins/cephalosporins is mainly related to side-chain similarities concerns first second-generation cephalosporins (2CG). Historic risk of 10-30% was probably overestimated, actual with different side chain third generation (3CG) could be around 1% (1). Our objective assess 3CG 2CG in penicillin-proven allergic patients. We conducted a retrospective study including 234 adults proven HS...