Roy P. Marcus

ORCID: 0000-0002-5456-7366
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Advanced X-ray and CT Imaging
  • Advanced MRI Techniques and Applications
  • Radiation Dose and Imaging
  • Medical Imaging Techniques and Applications
  • Shoulder Injury and Treatment
  • Cardiovascular Function and Risk Factors
  • Dental Radiography and Imaging
  • Lymphoma Diagnosis and Treatment
  • Shoulder and Clavicle Injuries
  • Ultrasound in Clinical Applications
  • Osteoarthritis Treatment and Mechanisms
  • Immune Response and Inflammation
  • Acute Myocardial Infarction Research
  • Advanced Radiotherapy Techniques
  • Radiation Therapy and Dosimetry
  • Chronic Lymphocytic Leukemia Research
  • Pediatric Urology and Nephrology Studies
  • Foot and Ankle Surgery
  • Inflammatory mediators and NSAID effects
  • Neuroendocrine Tumor Research Advances
  • Apelin-related biomedical research
  • Intestinal and Peritoneal Adhesions
  • Clinical practice guidelines implementation
  • Hormonal Regulation and Hypertension

University of Zurich
2023-2024

Anna Needs Neuroblastoma Answers
2024

Universitätsklinik Balgrist
2023-2024

Schulthess-Klinik
2024

University of Lucerne
2022-2023

Tilburg University
2023

Mayo Clinic
2018-2021

Odense University Hospital
2019

University of Kentucky
2019

Ludwig-Maximilians-Universität München
2011-2018

Purpose To determine the feasibility of computed tomography (CT)-based dynamic myocardial perfusion imaging for detection hemodynamically significant coronary artery stenosis, as defined with fractional flow reserve (FFR). Materials and Methods Institutional review board approval informed patient consent were obtained before enrollment in study. The study was HIPAA compliant. Subjects who suspected having or known to have disease underwent electrocardiographically triggered stress imaging....

10.1148/radiol.11110638 article EN Radiology 2011-08-16

<h3>Objectives</h3> To evaluate the diagnostic accuracy (DA) of CT-myocardial perfusion imaging (CT-MPI) and a combined approach with CT angiography (CTA) for detection haemodynamically relevant coronary stenoses in patients both suspected known artery disease. <h3>Design</h3> Prospective, non-randomised, study. <h3>Setting</h3> Academic hospital-based <h3>Patients</h3> 65 (42 men age 70.4±9) typical or atypical chest pain. <h3>Interventions</h3> CTA CT-MPI adenosine stress using fast...

10.1136/heartjnl-2013-303794 article EN Heart 2013-05-14

Objective: To determine the accuracy of computed tomography (CT) dynamic stress myocardial perfusion imaging to estimate blood flow (MBF) in a porcine animal model with variable degrees induced coronary artery stenosis comparison microsphere-derived MBF. Methods and Materials: Seven domestic pigs (36 ± 4 kg) received stents (confirmed 3.0 mm diameter) left anterior descending distal first diagonal branch. A balloon catheter was placed within stent inflated various obtain defined luminal...

10.1097/rli.0b013e31823fd42b article EN Investigative Radiology 2011-12-16

Purpose To compare a research photon-counting-detector (PCD) CT scanner to dual-source, dual-energy for the detection and characterization of renal stones in human participants with known stones. Materials Methods Thirty study (median age, 61 years; 10 women) underwent clinical stone scan by using subsequent PCD same radiation dose (as represented volumetric index). Two radiologists were tasked stones, which later characterized as uric acid or non-uric commercial analysis package. Stone size...

10.1148/radiol.2018180126 article EN Radiology 2018-08-07

Photon-counting detector (PCD) CT could be useful to help address the typically high radiation doses of conventional energy-integrating (EID) lumbar spine.

10.2214/ajr.23.29950 article EN American Journal of Roentgenology 2023-08-30

Objectives The aim of this study was to compare the effectiveness and clinical utility virtual monoenergetic image (VMI) reconstructions in computed tomography (CT) scans with without tin prefiltration on a photon-counting detector (PCD) CT system reduce metal implant artifacts postoperative ankle. Materials Methods This retrospective included patients internal fixation ankle scanned (Sn) PCD scanner between March October 2023. Virtual images 60 190 keV were reconstructed 10-keV increment...

10.1097/rli.0000000000001058 article EN cc-by-nc-nd Investigative Radiology 2024-01-10

10.1016/j.jmbbm.2017.07.028 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2017-07-20

The purpose of this study was to determine the feasibility global quantitative measurements left ventricular myocardial perfusion derived from stress dynamic CT imaging.The coronary angiographic and imaging datasets 146 patients were visually evaluated for presence artery stenosis defects. For analysis, volumes interest defined over entire myocardium obtain blood flow (MBF), volume (MBV), transfer constant (K(trans)).In without anatomically significant or defects, mean value MBF 137.9 ± 28.8...

10.2214/ajr.13.12328 article EN American Journal of Roentgenology 2014-05-21

To study the predictive value of whole-body magnetic resonance (MR) imaging for occurrence cardiac and cerebrovascular events in a cohort patients with diabetes mellitus (DM).This HIPAA-compliant was approved by institutional review board. Informed consent obtained from all before enrollment into study. The authors followed up 65 DM (types 1 2) who underwent comprehensive, contrast material-enhanced MR protocol, including brain, cardiac, vascular sequences at baseline. Follow-up performed...

10.1148/radiol.13130371 article EN Radiology 2013-09-11

This study aimed to evaluate the diagnostic accuracy, inter-reader agreement, and associated pathologies on MR images of patients with confirmed TC.

10.1007/s00330-023-10304-z article EN cc-by European Radiology 2023-10-19

The vertebral cartilage endplate (CEP), crucial for intervertebral disc health, is prone to degeneration linked chronic low back pain, degeneration, and Modic changes (MC). While it known that cells express toll-like receptors (TLRs) recognize pathogen- damage-associated molecular patterns (PAMPs DAMPs), unclear if CEP (CEPCs) share this trait. has a higher cell density than the disc, making CEPCs an important contributor. This study aimed identify TLRs on their role in pro-inflammatory...

10.3390/cells13171402 article EN cc-by Cells 2024-08-23

Objectives The aim of this study was to quantify and compare fat fraction (FF) muscle volume between patients with failed intact rotator cuff (RC) repair as well a control group nonsurgical conservative treatment define FF cutoff values for predicting the outcome RC repair. Materials Methods Patients full-thickness tears who received magnetic resonance imaging (MRI) before after including 2-point Dixon sequence were retrospectively screened. retear 1 or more tendons diagnosed on MRI (Sugaya...

10.1097/rli.0000000000001024 article EN cc-by-nc-nd Investigative Radiology 2023-09-14

Abstract Background Coronary computed tomography angiography has become the foremost noninvasive imaging modality of coronary arteries and is used as an alternative to reference standard, conventional angiography, for direct visualization detection artery stenoses in patients with suspected disease. Nevertheless, there considerable debate regarding optimal target population maximize clinical performance patient benefit. The most obvious indication disease would be reliably exclude...

10.1186/2046-4053-2-13 article EN cc-by Systematic Reviews 2013-02-15

To investigate and compare several quantification methods of myocardial perfusion measurements, paying special attention to the relation between techniques required measurement duration.Seven patients underwent contrast-enhanced rest stress cardiac measurements at 3T. Three slices were acquired in each patient divided into 16 segments, leading 112 data curves, which analyzed using various tracer kinetic models as well a model-free deconvolution. Plasma flow, plasma volume, reserve for...

10.1002/mrm.25212 article EN Magnetic Resonance in Medicine 2014-03-31

Objective Aim of this ex vivo phantom study was to evaluate the contrast enhancement applying a new frequency split nonlinear blending algorithm (best [BC]) and compare it with standard 120-kV single-energy computed tomography (SECT) images, as well low-kiloelectron volt monoenergetic extrapolations (Mono+ 40–100keV ) from dual-energy CT (DECT) low-kilovolt (70–100 kV) SECT acquisitions. Materials Methods A dilution series iodinated material–filled syringes centered in an attenuation scanned...

10.1097/rli.0000000000000293 article EN Investigative Radiology 2016-05-12
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