A5046201134- Intracranial Aneurysms: Treatment and Complications
- Organ Transplantation Techniques and Outcomes
- Glioma Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Moyamoya disease diagnosis and treatment
- Immune cells in cancer
- Clinical Nutrition and Gastroenterology
- Polysaccharides and Plant Cell Walls
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Seaweed-derived Bioactive Compounds
- Pharmacological Effects of Natural Compounds
- Mechanical stress and fatigue analysis
- Meningioma and schwannoma management
- Transplantation: Methods and Outcomes
- Organ Donation and Transplantation
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Renal Transplantation Outcomes and Treatments
- Cancer Immunotherapy and Biomarkers
- Hematopoietic Stem Cell Transplantation
- Neurological Complications and Syndromes
- Oropharyngeal Anatomy and Pathologies
Kyushu University
2002-2025
Koga Hospital
2015-2025
Kyoto first Red Cross hospital
2020-2024
Kyushu Rosai Hospital
2022-2023
Japanese Red Cross Society Kyoto Daini Hospital
2023
National Hospital Organization
2014-2015
Ureshino Medical Center
2015
Okayama Medical Center
1990-2014
Kochi Medical School Hospital
2007
Organ Technologies (Japan)
2004
Since 1986, percutaneous intradiscal laser nucleotomy (PILN) has been studied in the authors' laboratory. The purpose of this report is to develop PILN as an alternative chemonucleolysis and discectomy, which are currently applied, establish a safe, easy, accurate short-time therapy method for lumbar disc herniation. After irradiation, pressures (IDP) decreased nucleus pulposus was gradually replaced with cartilaginous fibrous tissue. evaluation heat distribution thermocouples thermography...
Combination therapy with ipilimumab and nivolumab is indicated for many types of cancers; however, several patients experience immune-related adverse events (irAEs). We herein report a case cytokine release syndrome (CRS) in 63-year-old woman stage IV left clear cell renal carcinoma. Our patient developed CRS while taking prednisolone, 43 days after the start administration. The was treated steroid pulse therapy, which improved symptoms shock respiratory failure. Increased vascular...
Targeting the unique glioma immune microenvironment is a promising approach in developing breakthrough immunotherapy treatments. However, recent advances immunotherapy, including development of checkpoint inhibitors, have not improved outcomes patients with glioma. A way monitoring biological activity cells neural tissues affected by should be developed to address this lack sensitivity immunotherapy. Thus, study, we sought examine feasibility non-invasive glioma-associated...
Angiogenic factors associated with Moyamoya disease (MMD) are overexpressed in M2 polarized microglia ischemic stroke, suggesting that may be involved the pathophysiology of MMD; however, existing approaches not applicable to explore this hypothesis. Herein we applied blood induced microglial-like (iMG) cells. We recruited 25 adult patients MMD and 24 healthy volunteers. Patients were subdivided into progressive (N = 7) or stable 18) group whether novel symptoms radiographic advancement...
Gliosarcomas are a type of bimorphic tumor composed glial and sarcomatous elements, considered to be variant glioblastoma, WHO grade IV. To date, only rare cases gliosarcoma with oligodendroglial components (oligosarcoma) have been reported. We report case oligosarcoma consisting arising from recurrent oligodendroglioma. A 53‐year‐old man, who had undergone gross total resection oligodendroglioma (WHO II) 11 years earlier, presented local recurrence. The patient underwent second resection,...
Surgical treatment of endodermal cysts requires total removal the cyst wall during first operation to prevent recurrence. Therefore, intraoperative pathological diagnosis plays an important role in determining optimal surgical strategy. We present a rare case spinal and discuss its diagnostic difficulty examination.An 18-year-old male presented with progressive paraparesis precordial oppression. Magnetic resonance (MR) imaging revealed intradural extramedullary cystic mass having same signal...
Lateralized periodic discharges (LPDs), which constitute an abnormal electroencephalographic (EEG) pattern, are most often observed in critically ill patients with acute pathological conditions, and less frequently chronic conditions such as focal epilepsies, including temporal lobe epilepsy (TLE). Here we aim to explore the pathophysiological mechanism of LPD TLE.We retrospectively selected 3 drug-resistant TLE who simultaneously underwent EEG electrocorticography (ECoG) demonstrated LPDs....
Cardiovascular malformations during embryogenesis can lead the inferior laryngeal nerve to branching directly from cervical vagus and entering larynx. This rare anatomical variation is known as a non-recurrent (NRILN), increases risk of accidental injury resulting in postoperative vocal cord paralysis neck surgery. We report case an 83-year-old man who presented with left symptomatic internal carotid artery stenosis right-sided aortic arch aberrant subclavian (ALSCA). performed...
Cranial nerve palsy occurring after carotid endarterectomy (CEA) is the most common recognized complication, along with others such as stroke and myocardial infarction (MI). We examined incidence follow-up of cranial other periprocedural major adverse events in 216 consecutive CEAs performed between January 2006 December 2012. Six palsies (2 dysphonia, 1 dysphagia, tongue hemiparesis, 2 first bite syndromes) were identified 4 patients (1.9%). All symptoms transient recovered within 3 months....
Sulcal hyperintensity on magnetic resonance images with fluid-attenuated inversion recovery sequences (FLAIR) can occur in patients without apparent cerebrospinal fluid (CSF) abnormalities. Taoka et al. speculated that pathological increases of the blood pool to CSF ratio within sulcus, which could be caused by alterations regional hemodynamics including venous congestion, do not suppress water signals FLAIR images. However, few previous reports have described sulcal chronic subdural...
Vagus nerve stimulation (VNS) is a well-known palliative therapy for refractory epilepsy. However, some non-responsive patients experience persistent epileptic seizures after VNS. Aiming to identify the factors affecting response VNS, we retrospectively analyzed temporal relationship between VNS and ictal discharges through electroencephalographic electrocorticographic monitoring in patient. We performed an 8-year-old boy suffering from posttraumatic epilepsy first presurgical evaluation. no...
Abstract INTRODUCTION: As recent advancement of multimodal treatments including immune-check point inhibitors have not led to massive outcome improvement glioma. Targeting the peculiar immune microenvironment glioma is a promising approach innovate breakthrough treatment, however, there remains be technical and ethical burdens for monitoring bioactivities cells in neural tissues. Herein, we examined feasibility non-invasive glioma-associated microglia/macrophages (GAM) properties through...
O394* Aims: Kidney transplant (KTx) from non-heart-beating donors (NHBD) would be one of the countermeasures dealing with organ shortage. In present study, contributing factors to influence early graft function after KTx NHBD were investigated. Methods: Since April 1995, 1279 cases deceased donor done in Japan. 876 among them, triple-lumen/double-balloon catheter (TR/DBC) for situ perfusion (ISP) was inserted into abdominal aorta via femoral vessels before cardiac standstill (CS) and ISP...