- Spinal Dysraphism and Malformations
- Cerebrospinal fluid and hydrocephalus
- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Head and Neck Surgical Oncology
- Neurosurgical Procedures and Complications
- Teratomas and Epidermoid Cysts
- Cerebrovascular and Carotid Artery Diseases
- Spinal Cord Injury Research
- Intracranial Aneurysms: Treatment and Complications
- Spinal Hematomas and Complications
- Neuroscience and Neuropharmacology Research
- Intracerebral and Subarachnoid Hemorrhage Research
- EEG and Brain-Computer Interfaces
- Fetal and Pediatric Neurological Disorders
- Neurological Complications and Syndromes
- Congenital Anomalies and Fetal Surgery
- Vascular Malformations Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Neurological and metabolic disorders
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
Kyushu University
2016-2025
Fukuoka Children's Hospital and Medical Center for Infectious Diseases
2015-2022
Kyushu Rosai Hospital
2013-2020
Kyoto University
2017-2020
Japan Organization of Occupational Health and Safety
2013-2015
Creative Research Enterprises (United States)
2014
Background: Our recent report showed that 1.5-T pulsed arterial spin labeling (ASL) magnetic resonance (MR) perfusion imaging (1.5-T Pulsed ASL [PASL]), which is widely available in the field of neuroemergency, useful for detecting ictal hyperperfusion. However, visualization intravascular signals, namely, transit artifact (ATA), more remarkable than 3-T pseudocontinuous and easily confused with focal To eliminate ATA enhance detectability (peri) hyperperfusion, we developed subtraction...
Magnetic resonance imaging (MRI), including perfusion MRI with arterial spin labeling (ASL) and diffusion-weighted (DWI), are applied in the periictal detection of circulatory metabolic consequences associated epilepsy. Although previous report revealed that prolonged ictal hyperperfusion on ASL can be firstly detected cortical hyperintensity cytotoxic edema DWI secondarily obtained from an epileptically activated cortex, hemodynamic state has not been fully demonstrated. We retrospectively...
Magnetic resonance imaging (MRI), including perfusion MRI with three-dimensional pseudocontinuous arterial spin labeling (ASL) and diffusion-weighted (DWI), are applied in the periictal (including ictal postictal) detection of circulatory metabolic consequences associated epilepsy. Our previous report revealed that hyperperfusion can firstly be detected on ASL, cortical hyperintensity cytotoxic edema secondarily obtained DWI from an epileptically activated cortex. Although magnetic...
Arterial spin labeling (ASL) imaging with multiple postlabeling delays (PLD) can demonstrate the hemodynamics of peri-ictal hyperperfusion. Labeling methods include pulsed ASL (PASL) and pseudocontinuous (pCASL). Although PASL is more widely used in daily clinical practice, it has several disadvantages because lower delivery labeled magnetization. We compared pCASL images acquired after a 24-h interval, using 1.5-Tesla machine, 62-year-old man non-convulsive status epilepticus. The during...
The hemodynamics of ictal hyperperfusion in dual pathology was evaluated using arterial spin labeling perfusion images (ASL) with triple postlabeling delays (PLDs). A 62-year-old man epileptogenic right parietal hematoma cavity and bilateral hippocampal atrophy, particularly on the right, underwent ASL examination during subtle non-convulsive status epilepticus immediately after focal-to-bilateral tonic-clonic seizures. at PLD 1.5 s showed increased signals gray matter both hemispheres,...
Recent our reports showed that 3-T pseudocontinuous arterial spin labeling (3-T pCASL) magnetic resonance perfusion imaging with dual post delay (PLD) of 1.5 and 2.5 s clearly demonstrated the hemodynamics ictal hyperperfusion associated non-convulsive status epilepticus (NCSE). We aimed to examine utility 1.5-T pulsed (1.5-T PASL), which is more widely available for daily clinical use, detecting hyperperfusion.We retrospectively analyzed findings PASL PLD 2.0 in six patients compared...
Background: Cell transplantation is expected to be a promising treatment for Parkinson's disease (PD), in which reinnervation of the host striatum by grafted dopamine (DA) neurons essential.In particular, dorsolateral part important because it target midbrain A9 DA neurons, are degenerated PD pathology.The effect exercise on survival and maturation has been reported several neurological models, but never models.Objective: We investigated how influences cell PD, especially from viewpoint...
<h3>BACKGROUND AND PURPOSE:</h3> The champagne bottle neck sign represents a rapid reduction in the extracranial ICA diameters and is characteristic feature of Moyamoya disease. However, clinical significance unclear. We investigated relationship between hemodynamic stages <h3>MATERIALS METHODS:</h3> analyzed 14 patients with disease before revascularization (5 men, 9 women; age, 43.2 ± 19.3 years). ratio common carotid artery was determined using ultrasonography or cerebral angiography;...
To examine the national, 6-year trends in in-hospital clinical outcomes of patients with subarachnoid haemorrhage (SAH) who underwent clipping or coiling and prognostic influence temporal Comprehensive Stroke Center (CSC) capabilities on patient Japan.
<b><i>Background:</i></b> An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. <b><i>Method:</i></b> Six out of 50 patients malformations had ependymal structures. We retrospectively analyzed clinical, neuroradiological, and histological findings these to demonstrate relationship background retained medullary cord...
Arterial spin-labeling magnetic resonance perfusion imaging (ASL-MRI) allows noninvasive measurement of cerebral blood flow (CBF) but depends on arterial transit time (ATT). To overcome this problem, we developed a simple ASL technique with dual postlabeling delay (PLD) settings. In addition to the routinely used PLD 1.5 seconds, selected another 2.5 seconds assess slowly streaming and detect artifacts (ATAs) resulting from stagnant intravascular magnetically labeled spins.We validated...
Abstract Background “Onset seizures” are acute symptomatic seizures occurring within 24 h after the onset of ischemic stroke, and their pathophysiological states unknown. Electroencephalography is commonly used to diagnose epileptic activities; however, it limited for use with stroke. Magnetic resonance imaging, including diffusion‐weighted imaging perfusion arterial spin labeling, applied mainly in an emergency. Ictal hyperperfusion on labeling cortical hyperintensity cytotoxic edema...