- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- MicroRNA in disease regulation
- Gastroesophageal reflux and treatments
- Colorectal and Anal Carcinomas
- Gastrointestinal disorders and treatments
- Metastasis and carcinoma case studies
- Dysphagia Assessment and Management
- Cancer-related gene regulation
- RNA Research and Splicing
- Ubiquitin and proteasome pathways
- Anorectal Disease Treatments and Outcomes
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Meningioma and schwannoma management
- Stoma care and complications
- Colorectal Cancer Screening and Detection
- Enhanced Recovery After Surgery
- Diverticular Disease and Complications
- Pelvic floor disorders treatments
- Cancer Cells and Metastasis
- Cancer-related Molecular Pathways
- Neurofibromatosis and Schwannoma Cases
Anhui Provincial Children's Hospital
2024
Anhui Medical University
2024
Second Xiangya Hospital of Central South University
2015-2024
Central South University
2015-2024
Yangpu Hospital of Tongji University
2017-2024
Hunan Provincial Center for Disease Control and Prevention
2024
Fifth Affiliated Hospital of Zhengzhou University
2024
Qingdao University
2008-2023
Tongji University
2020-2023
Sichuan University
2015-2022
Quantitative PCR (qPCR), the most accurate and sensitive technique for quantifying mRNA expression, choice of appropriate reference genes internal error controlling in qPCR are essential to understanding molecular mechanisms that drive obesity epidemic its comorbidities. In this study, using high-fat diet (HFD)-induced obese mouse model, we assessed expression 10 commonly used validate gene-expression stability adipose tissue, liver, muscle across different time points (4, 8, 12, 16 weeks...
Accumulating evidence indicates that aberrant expression of microRNAs is involved in tumorigenesis, tumor progression and response to therapy. MicroRNA-375 (miR-375) an important cancer-associated RNA downregulated multiple types cancer. In the present study, potential effects underlying molecular mechanism for miR-375 esophageal cancer were investigated. The paired squamous cell carcinoma (ESCC) non-tumor tissues from 10 patients was quantified using reverse transcription-quantitative...
BACKGROUND:Although many attempts have been made to advance the treatment of complex anal fistula, it continues be a difficult surgical problem. This study aimed describe novel technique video-assisted fistula (VAAFT) and our preliminary experiences using VAAFT with patients fistula. MATERIAL AND METHODS:From May 2015 2016, 52 were treated at Yangpu Hospital Tongji University School Medicine, clinical data these reviewed. RESULTS:VAAFT was performed successfully in all patients. The median...
Selective circular myotomy (CM) is recommended in peroral endoscopic (POEM) for achalasia, but completeness of myotmoy the prerequisite excellent long-term results conventional surgical myotomy. The aim our study was to compare efficacy and safety between full-thickness simple CM treatment severe achalasia.A total 123 achalasia patients who underwent POEM from August 2011 May 2013 were included. They divided into or (FTM) groups according depth Demographics, Eckardt score, procedure-related...
Both peroral endoscopic myotomy (POEM) and pneumatic dilation (PD) has proved to be effective for treating achalasia in patients aged ≥ 65 years. However little is known about the comparison between POEM PD. The aim of study was compare safety efficacy PD treatment these patients.We retrospectively reviewed medical records years-old or more who received at our hospital from January 2010 December 2015, they were divided into group group. Demographics data collected compared two groups.A total...
Tumor-associated fibroblasts are the most abundant population in tumor stroma and impact on initiation progression. However, biological function of tumor-associated pituitary adenomas has not been fully elucidated to date. So, this study aims clarify significance primary cultured adenoma-derived rat adenoma cells. We identified normal based expression α-smooth muscle actin as well morphology. Furthermore, we investigated cell influences cells through indirectly co-culturing with GH3...
MicroRNA (miR)-196a is upregulated in various types of malignancy, including esophageal squamous cell carcinoma (ESCC); however, its role ESCC currently unclear. The present study aimed to investigate the biological and molecular mechanism miR-196a ESCC. expression levels 25 tumor tissues adjacent non-tumor from patients with were measured by reverse transcription-quantitative polymerase chain reaction. In addition, assessed human normal epithelial line Het-1A EC109. effects on...
Abstract Intraventricular meningiomas are rather rare and only represent a small proportion of all intracranial meningiomas. Data still limited toward this peculiar entity surgical resection remains challenging for neurosurgeons. The purpose present study is to demonstrate clinical features, treatment, potential risk factors determined long-term prognosis intraventricular A total 89 surgically treated histopathologically confirmed were identified in our institution from 2008 2018. Clinical...