A5066153091- Smoking Behavior and Cessation
- Gestational Diabetes Research and Management
- Prenatal Screening and Diagnostics
- Maternal and Perinatal Health Interventions
- Obesity, Physical Activity, Diet
- Pregnancy and preeclampsia studies
- Vaccine Coverage and Hesitancy
- Medicinal Plant Extracts Effects
- Pelvic floor disorders treatments
- Congenital Heart Disease Studies
- Cervical Cancer and HPV Research
- Maternal and fetal healthcare
- Endometrial and Cervical Cancer Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Hormonal Regulation and Hypertension
- Nicotinic Acetylcholine Receptors Study
- Adrenal and Paraganglionic Tumors
- Streptococcal Infections and Treatments
- Empathy and Medical Education
- Cardiovascular Issues in Pregnancy
- Carcinogens and Genotoxicity Assessment
- Cannabis and Cannabinoid Research
- Infective Endocarditis Diagnosis and Management
- Global Maternal and Child Health
- Air Quality and Health Impacts
University of Minnesota
2018-2025
University of Minnesota Medical Center
2019-2024
University of Minnesota System
2019-2024
Twin Cities Orthopedics
2022-2023
University of North Carolina at Chapel Hill
2022
University of Minnesota, Duluth
2020-2022
Masonic Cancer Center
2018-2021
Kansas City Public Schools
2019
Highlights•Real-world data shows synergistic benefits of combining both AC and CCS.•Large study finds reduced TE events bleeding risks with combined CCS.•AC alone is linked to the lowest mechanical ventilation mortality.•CCS without associated worse outcomes reflecting severe baseline disease.•Findings bridge trial-practice gap offer insights COVID-19 treatment outcomes.AbstractBackgroundThe pandemic has led widespread use anticoagulation (AC) corticosteroids (CCS) for hospitalized patients,...
Cellular immunotherapy using allogeneic natural killer (NK) cells may overcome chemotherapy-refractory acute myeloid leukemia. Our goal was to document NK cell homing/persistence in the bone marrow following adoptive immunotherapy. cohort included 109 patients who received therapy for refractory leukemia lymphodepleting conditioning +/- denileukin diftitox, low-dose total body irradiation. We evaluated density core biopsies performed an average of 14 days after transfer a CD56...
Abstract Objective National studies report that birth center care is associated with reduced racial and ethnic disparities experiences of mistreatment. In the US, there are very few BIPOC-owned centers. This study examines impact culturally-centered delivered at Roots, a Black-owned center, on experience client autonomy respect. Methods To investigate if was an association between respect for Roots versus national Giving Voice to Mothers (GVtM) participants, we applied Wilcoxon rank-sum...
Objective To pilot test QuitGuide for Natives, a culturally aligned version of the National Cancer Institute’s smartphone app smoking cessation. Methods This randomised controlled trial was conducted remotely during 2022–2023. American Indian adults who smoked and resided in Midwest (n=115) were to Natives or general audience smartphone-based intervention. Group differences feasibility (times initiated), usability, acceptability (‘How likely would you be recommend friend?’), fit with culture...
Tobacco smoking is the primary risk factor for lung cancer, driven by addictive nature of nicotine and indisputable carcinogenicity 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) as well other compounds. The integration cancer chemoprevention with cessation one potential approach to reduce this mitigate mortality. Experimental data from our group suggest that kava, commonly consumed in South Pacific Islands a beverage promote relaxation, may enhancing NNK detoxification reducing...
Objective: Despite calls to incorporate research training into medical school curriculum, minimal has been conducted elucidate trends in knowledge, opportunities, and involvement globally. This study aims to: (1) assess students’ perceptions of the level they received on based their training, (2) evaluate obstacles related conducting as part training. Methods: A 94-question, bilingual survey designed by a small focus group individuals from schools across globe administered students different...
A mandated reduction in the nicotine content of cigarettes could reduce smoking rate and prevalence. However, one concern is that smokers may compensate by increasing intensity with which they smoke each cigarette to obtain more nicotine. This study assessed whether engage compensatory estimating mouth-level intake low smoked during a clinical trial. Smokers were randomly assigned receive five contents for 6 weeks. An additional group received lowest content, but an increased tar yield. The...
Menthol and filter ventilation (FV) contribute to cigarette appeal. This observational study examines the US prevalence of menthol versus non-menthol use by FV how harm perceptions, cigarettes per day biomarkers exposure vary.
Our study aims to understand public knowledge of postmenopausal bleeding as an endometrial cancer symptom and how past provider counseling on affects care-seeking behaviors related bleeding.
The Infectious Diseases Society of America recommends a screening dilated retinal examination by an ophthalmologist for all patients with candidemia. Conversely, the American Academy Ophthalmology against routine in candidemia without symptoms.
Abstract 2-Phenethyl isothiocyanate (PEITC) is a natural product found as conjugate in cruciferous vegetables. It has been reported to have preventative properties against lung cancer and inhibit metabolic activation of tobacco carcinogens. In this study, we evaluated the ability PEITC influence metabolism human carcinogen 1,3-butadiene current smokers phase II clinical trial with crossover design. Urinary mercapturic acids were quantified at baseline during treatment. Seventy-nine randomly...
Abstract Introduction Studies suggest tobacco and cannabis co-users may experience greater toxicant exposure than exclusive cigarette (ET) smokers. No study has systematically tested differences in among co-users, (ECa) smokers, ET Aims Methods Adult daily smokers and/or weekly completed two laboratory visits. Co-users (n = 19) positive for urinary 11-nor-9-carboxy-Δ 9-tetrahydrocannabinol (THCCOOH), self-reported use ≥1 per week, smoked ≥5 cigarettes day (CPD). 18) denied past month use,...
Human exposure to known carcinogen 1,3-butadiene (BD) is common due its high concentrations in automobile exhaust, cigarette smoke, and forest fires, as well widespread use the polymer industry. The adverse health effects of BD are mediated by epoxide metabolites such 3,4-epoxy-1-butene (EB), which reacts with DNA form 1-hydroxyl-3-buten-1-yl adducts on nucleobases. EB-derived mercapturic acids (1- 2-(N-acetyl-l-cysteine-S-yl)-1-hydroxybut-3-ene (MHBMA)...
Background While evidence demonstrates that the industry’s marketing of cigarettes with higher filter ventilation (FV) misleads adults about their health risks, there is no research on relationships between FV, risk perceptions and smoking trajectories among youth (ages 12–17) young 18–24). Methods Data FV levels major US cigarette brands/sub-brands were merged Population Assessment Tobacco Health Study to examine whether level in used by wave 1 youth/young (n=1970) predicted continued at...
A nicotine product standard reducing the content in cigarettes could improve public health by smoking. This study evaluated potential unintended consequences of a reduced examining its effects on (1) smoking behaviors based drinking history; (2) behavior; and (3) daily associations between drinking. Adults who smoke (n = 752) United States were randomly assigned to very low (VLNC) versus normal (NNC; control) for 20 weeks. Linear mixed models determined if baseline moderated VLNC NNC Week...