- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Innovations in Medical Education
- Cardiac Arrest and Resuscitation
- SARS-CoV-2 and COVID-19 Research
- Oral and gingival health research
- Pharmaceutical Practices and Patient Outcomes
- Pharmacological Effects and Toxicity Studies
- Acute Myocardial Infarction Research
- Sepsis Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences Research and Education
- Cardiac Arrhythmias and Treatments
- Interprofessional Education and Collaboration
- Long-Term Effects of COVID-19
- Hematological disorders and diagnostics
- Pancreatitis Pathology and Treatment
- Electrolyte and hormonal disorders
- Renal Transplantation Outcomes and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Problem and Project Based Learning
- Evaluation of Teaching Practices
- Nausea and vomiting management
University of Minnesota
2015-2025
Twin Cities Orthopedics
2021
University of Minnesota, Duluth
2021
Fairview Health Services
2021
American College of Clinical Pharmacy
2020
North Memorial Health Care
2009-2020
University of Minnesota System
2020
University of Wisconsin–Madison
2016
North Memorial Medical Center
2008-2015
University of Nevada, Reno
2011
Background: Prothrombin complex concentrate (PCC) is recommended as a therapy to be considered for the reversal of warfarin's effects. Few published data are available on use PCC this indication in traumatically injured patients. Objective: To determine whether addition standard approaches warfarin more rapidly corrects international normalized ratio (INR) Methods: A retrospective analysis was performed trauma patients who were preinjury from January 2007 September 2009 at North Memorial...
Highlights•Real-world data shows synergistic benefits of combining both AC and CCS.•Large study finds reduced TE events bleeding risks with combined CCS.•AC alone is linked to the lowest mechanical ventilation mortality.•CCS without associated worse outcomes reflecting severe baseline disease.•Findings bridge trial-practice gap offer insights COVID-19 treatment outcomes.AbstractBackgroundThe pandemic has led widespread use anticoagulation (AC) corticosteroids (CCS) for hospitalized patients,...
Although cooked potato tuber texture is an important trait that influences consumer preference, a detailed understanding of textural properties at the molecular level lacking. Previous work has identified pectin methyl esterase activity (PME) as potential factor impacting on properties. In this study, PME isoform and gene expression profiles have been determined in germplasm with differing assessed using amended wedge fracture method sloughing assay, revealing major differences between...
OBJECTIVE To report 2 cases of acute renal failure (ARF) following administration sucrose-stabilized intravenous immune globulin (IVIG), one which did not recur subsequent doses d-sorbitol–stabilized formulation, and review the relevant literature. CASE SUMMARIES A 44-year-old white man awaiting heart transplantation developed ARF requiring hemodialysis IVIG for high alloreactivity to population human leukocyte antigens. Following a return function baseline, were administered without...
The Colorado potato beetle, Leptinotarsa decemlineata (Say), is a major agricultural pest of commercial potatoes. Pest managers use combination control tactics to limit populations, including multiple insecticides. Finding window insecticide susceptibility and understanding genetic responses exposure during growing season may provide novel management recommendations for L. decemlineata.We examined temporal changes (during one season) in phenotypic response between susceptible population an...
Objectives To determine the rate of portal vein thrombosis (PVT) based on pharmacologic prophylaxis protocol and impact PVT islet graft function after total pancreatectomy with autotransplantation (TPIAT). Methods We compared incidence PVT, postsurgical bleeding, thrombotic complications in patients undergoing TPIAT between 2001 2018 at University Minnesota who received either unfractionated heparin (UFH) or enoxaparin for postoperative prophylaxis. Six-month 1-year was developed those did...
Objective The purpose of this study was to determine the type arrhythmias induced with therapeutic versus diagnostic transthoracic low-frequency ultrasound (TLFUS) transducers in presence intravenous microbubbles. Methods Intravenous perfluorocarbon-exposed sonicated dextrose albumin (PESDA) microbubbles were infused or given as a bolus injection while TLFUS applied standard parasternal and apical views either 1-MHz transducer high-mechanical-index (1.7 MHz). Results Significantly more...
Prothrombin complex concentrate (PCC) and recombinant Factor VIIa (rFVIIa) have been used for emergent reversal of warfarin anticoagulation. Few clinical studies compared these agents in reversal. We patients who received either 3 factor PCC (PCC3) or low-dose rFVIIa (LDrFVIIa) anticoagulation.Data were collected from medical charts at least one dose PCC3 (20 units/kg) LDrFVIIa (1000 1200 mcg) August 2007 to October 2011. The primary end-points achievement an INR 1.5 less efficacy...
Abstract High‐quality experiential education builds on didactic to enable graduates meet the full spectrum of entry‐level pharmacy‐related roles and responsibilities, including lifelong learning professional development. The 2019 Educational Affairs Committee A, an ACCP standing committee, was charged review update 2008 white paper position statement quality education. main objective this is provide colleges schools pharmacy (C/SOPs) affiliated partners in with practices expected assist...
Ischemic stroke is a risk associated with atrial fibrillation (AF) and estimated to occur five times more often in afflicted patients than those without AF. Anti-thrombotic therapy recommended for the prevention of ischemic stroke. Risk stratification tools, such as CHADS2, recently CHA2DS2-VASc, predicting AF have been developed determine level assist clinicians selection antithrombotic therapy. Warfarin, AF, most commonly prescribed anticoagulant North America. The purpose this study was...
Objective. To determine if the number of patient encounters during advanced pharmacy practice experiences (APPEs) relates to student self-assessment care skills using entrustable professional activities (EPAs).Methods. During 12-week acute care/institutional (AC/INST) APPEs, 15-week combined community and ambulatory (CPAC) three 5-week AC/INST or CPAC elective fourth-year students completed tracking surveys. Students documented encounters, type provided, primary secondary diagnoses, special...
Abstract Objective To determine the impact of acute SARS-CoV-2 infection on patient with concomitant active cancer and CVD. Methods The researchers extracted analyzed data from National COVID Cohort Collaborative (N3C) database between January 1, 2020, July 22, 2022. They included only patients infection, defined as a positive test by PCR 21 days before 5 after day index hospitalization. Active cancers were last drug administered within 30 admission. “Cardioonc” group consisted CVD cancers....