Nabeel Qureshi
A5103121290- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- COVID-19 Impact on Reproduction
- Machine Learning in Healthcare
- COVID-19 diagnosis using AI
- Sepsis Diagnosis and Treatment
- Healthcare cost, quality, practices
- Data-Driven Disease Surveillance
- Chronic Disease Management Strategies
- Maternal and fetal healthcare
- Grit, Self-Efficacy, and Motivation
- Hemophilia Treatment and Research
- COVID-19 Digital Contact Tracing
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 epidemiological studies
- Abdominal Surgery and Complications
- Healthcare Systems and Challenges
- Pharmacogenetics and Drug Metabolism
- Artificial Intelligence in Healthcare and Education
- HIV/AIDS Research and Interventions
- Artificial Intelligence in Healthcare
- Kawasaki Disease and Coronary Complications
- Medical Coding and Health Information
- HIV/AIDS Impact and Responses
RAND Corporation
2024
University of Nottingham
2024
Hackensack Meridian Health
2020-2021
Addenbrooke's Hospital
2019
Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational clinical are abundant, these largely inaccessible to outside researchers. Statistical, machine learning, causal analyses most successful with large-scale beyond what is available in any given organization. Here, we introduce the National COVID Cohort Collaborative (N3C), an open science community focused on analyzing patient-level from many centers.The...
The National COVID Cohort Collaborative (N3C) is a centralized, harmonized, high-granularity electronic health record repository that the largest, most representative COVID-19 cohort to date. This multicenter data set can support robust evidence-based development of predictive and diagnostic tools inform clinical care policy.
The majority of U.S. reports COVID-19 clinical characteristics, disease course, and treatments are from single health systems or focused on one domain. Here we report the creation National COVID Cohort Collaborative (N3C), a centralized, harmonized, high-granularity electronic record repository that is largest, most representative cohort cases controls to date. This multi-center dataset supports robust evidence-based development predictive diagnostic tools informs critical care policy.In...
Abstract Objective In response to COVID-19, the informatics community united aggregate as much clinical data possible characterize this new disease and reduce its impact through collaborative analytics. The National COVID Cohort Collaborative (N3C) is now largest publicly available HIPAA limited dataset in US history with over 6.4 million patients a testament partnership of 100 organizations. Materials Methods We developed pipeline for ingesting, harmonizing, centralizing from 56...
Prior observational studies suggest that aspirin use may be associated with reduced mortality in high-risk hospitalized patients COVID-19, but aspirin's efficacy moderate COVID-19 is not well studied.To assess whether early lower odds of in-hospital COVID-19.Observational cohort study 112 269 enrolled from January 1, 2020, through September 10, 2021, at 64 health systems the United States participating National Institute Health's COVID Cohort Collaborative (N3C).Aspirin within first day...
Abstract Objective The goals of this study were to harmonize data from electronic health records (EHRs) into common units, and impute units that missing. Materials Methods National COVID Cohort Collaborative (N3C) table laboratory measurement data—over 3.1 billion patient over 19 000 unique concepts in the Observational Medical Outcomes Partnership (OMOP) common-data-model format 55 partners. We grouped ontologically similar OMOP together for 52 variables relevant COVID-19 research,...
Abstract Objective This study sought to evaluate whether synthetic data derived from a national coronavirus disease 2019 (COVID-19) dataset could be used for geospatial and temporal epidemic analyses. Materials Methods Using an original (n = 1 854 968 severe acute respiratory syndrome 2 tests) its derivative, we compared key indicators of COVID-19 community spread through analysis aggregate zip code-level curves, patient characteristics outcomes, distribution tests by code, indicator counts...
Patients with coronavirus disease 2019 (COVID-19) often experience persistent symptoms, known as postacute sequelae of COVID-19 or long COVID, after severe acute respiratory syndrome 2 (SARS-CoV-2) infection. Chronic lung (CLD) has been identified in small-scale studies a potential risk factor for COVID. This large-scale retrospective cohort study using the National COVID Cohort Collaborative data evaluated link between CLD and over 6 months SARS-CoV-2 We included adults (aged ≥18 years) who...
Rates of obesity are rising in patients with inflammatory bowel disease [IBD]. We conducted a US population-based study to determine the effects on outcomes hospitalised IBD.We searched Nationwide Readmissions Database 2016-2017 identify all adult for IBD, using ICD-10 codes. compared obese (body mass index [BMI] ≥ 30) vs non-obese [BMI < 30] IBD evaluate independent readmission, mortality, and other hospital outcomes. Multivariate regression propensity matching were performed.We identified...
Exogenous estrogen is associated with reduced coronavirus disease (COVID) mortality in nonimmunosuppressed/immunocompromised (non-ISC) postmenopausal females. Here, we examined the association of or testosterone hormone replacement therapy (HRT) COVID outcomes solid organ transplant recipients (SOTRs) compared to non-ISC individuals, given known differences sex-based risk these populations. SOTRs ≥45 years old COVID-19 between April 1, 2020 and July 31, 2022 were identified using National...
Abstract Background Anticoagulation (AC) utilization patterns and their predictors among hospitalized coronavirus disease 2019 (COVID-19) patients have not been well described. Methods Using the National COVID Cohort Collaborative, we conducted a retrospective cohort study (2020–2022) to assess AC use identify factors associated with therapeutic employing modified Poisson regression. Results Among 162 842 COVID-19 patients, 64% received 24% AC. Therapeutic declined from 32% in 2020 12% 2022,...
Abstract Objective To determine the impact of acute SARS-CoV-2 infection on patient with concomitant active cancer and CVD. Methods The researchers extracted analyzed data from National COVID Cohort Collaborative (N3C) database between January 1, 2020, July 22, 2022. They included only patients infection, defined as a positive test by PCR 21 days before 5 after day index hospitalization. Active cancers were last drug administered within 30 admission. “Cardioonc” group consisted CVD cancers....
Antithyroid drug-induced severe liver injury is an uncommon but serious complication. We hereby delineate the case of a 38-year-old female who presented to emergency department for impending thyroid storm. After initiation single dose propylthiouracil, her enzymes went into thousands. She was subsequently admitted intensive care unit. Propylthiouracil discontinued and corticosteroids were initiated with resolution elevated enzymes. On follow-up, function at its baseline hormone levels under...
The COVID-19 pandemic has changed the delivery of surgical care.Early in pandemic, an association between SARS-CoV-2 infection and adverse postoperative outcomes prompted implementation risk mitigation strategies, including routine asymptomatic testing postponement procedures 1-3 .In May 2023, WHO declared end to global public health emergency; however, disease's implications with regard perioperative care persist.As novel variants emerge, understanding influence reinfection on is important...
We propose and validate a domain knowledge-driven classification model for diagnosing post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID, using Electronic Health Records (EHRs) data.
Abstract Background Familial Hypercholesterolaemia (FH) is a greatly underdiagnosed genetic lipid disorder with high risk of morbidity from premature cardiovascular disease. However, early diagnosis can significantly reduce lipid-lowering medicines. Patients identified primary dyslipidaemia are recommended for clinic referral to inform patient management. Improving FH identification and addressing ethnic disparities in management, current NHS priority the UK. Aim We aimed explore...
South Africa's Central Chronic Medicine Dispensing and Distribution (CCMDD) program provides community-based medication delivery for clinically stable people with HIV (PWH) on antiretroviral therapy (ART). To evaluate CCMDD implementation, we conducted semi-structured interviews 60 PWH enrolled in at least 12 months. In a directed content analysis based the Practical, Robust Implementation Sustainability Model (PRISM) implementation science framework, key themes were compared qualitative...
ObjectiveThe effects of Coronavirus disease 2019 (COVID-19) infection and altered processes care on nonelective coronary artery bypass grafting (CABG) outcomes remain unknown. We hypothesized that patients with COVID-19 would have longer hospital lengths stay greater mortality compared COVID-negative patients, but these not differ between pre-COVID controls.MethodsThe National COVID Cohort Collaborative 2020-2022 was queried for adult undergoing CABG. Patients were divided into...