A5045795759- COVID-19 Clinical Research Studies
- Education Systems and Policy
- Diabetes and associated disorders
- Evolution and Genetic Dynamics
- Data Quality and Management
- Labor market dynamics and wage inequality
- Long-Term Effects of COVID-19
- Software Engineering and Design Patterns
- Liver Disease Diagnosis and Treatment
- Genetic diversity and population structure
- Scientific Computing and Data Management
- Entrepreneurship Studies and Influences
- COVID-19 and healthcare impacts
- Electronic Health Records Systems
- Mobile and Web Applications
- Nursing Diagnosis and Documentation
- Aquatic Invertebrate Ecology and Behavior
- Hepatitis C virus research
- Big Data and Business Intelligence
- Biomedical Text Mining and Ontologies
- Diabetes Management and Research
- Mathematical and Theoretical Epidemiology and Ecology Models
- Cultural Industries and Urban Development
- Plant and animal studies
- Engineering and Information Technology
University of Minnesota
2016-2025
Collaborative Research Group
2021-2024
Cohort (United Kingdom)
2021-2024
Duke University Health System
2024
Center For Policy Research
2024
Mayo Clinic in Florida
2024
HCA Healthcare
2024
Association of Perioperative Registered Nurses
2024
Leeds Trinity University
2023-2024
National Renewable Energy Laboratory
2022-2023
Harmonized data quality (DQ) assessment terms, methods, and reporting practices can establish a common understanding of the strengths limitations electronic health record (EHR) for operational analytics, improvement, research. Existing published DQ terms were harmonized to comprehensive unified terminology with definitions examples organized into conceptual framework support approach defining whether EHR is 'fit' specific uses.DQ publications, informatics analytics experts, managers...
Abstract Objective In response to COVID-19, the informatics community united aggregate as much clinical data possible characterize this new disease and reduce its impact through collaborative analytics. The National COVID Cohort Collaborative (N3C) is now largest publicly available HIPAA limited dataset in US history with over 6.4 million patients a testament partnership of 100 organizations. Materials Methods We developed pipeline for ingesting, harmonizing, centralizing from 56...
In March 2020, the White House Coronavirus Task Force determined that clinicians in United States needed expert treatment guidelines to optimally manage patients with COVID-19, a potentially life-threatening disease caused by new pathogen for which no specific treatments were known be effective.
Healthcare datasets obtained from Electronic Health Records have proven to be extremely useful for assessing associations between patients' predictors and outcomes of interest. However, these often suffer missing values in a high proportion cases, whose removal may introduce severe bias. Several multiple imputation algorithms been proposed attempt recover the information under an assumed missingness mechanism. Each algorithm presents strengths weaknesses, there is currently no consensus on...
Abstract Purpose – This article proposes the development of a conceptual model to help understand nature management learning in micro business context and inform research policy discourse. Design/methodology/approach The is developed on basis literature search review academic grey literature. Findings highlights unique environment. Meeting diverse interests managers major challenge for agencies seeking promote deliver leadership skills. An intervention approach founded upon relationship...
The authors examine factors that influence the propensity of a firm to take up external business support across four large English towns, using random effects nominal probit regression analysis capture sector heterogeneity. results suggest strong positive association between orientation towards growth and its use advice. ‘Push’ factors, including existence recruitment difficulties, are identified as key triggers These provide valuable guidance public policy organisations concerned with...
We investigated three possible causes of the increased ratio amylase/creatinine clearance observed in acute pancreatitis. The presence rapidly cleared isoamylase was excluded by studies serum and urine, which demonstrated no anomalous isoamylases. In pancreatitis, ratios (±1 S.E.M.) both pancreatic (9.2±0.6 per cent) salivary (8.6±1.6 were significantly (P<0.01) elevated over respective control values (2.4±0.2 1.8±0.2 cent). Increased glomerular permeability to amylase demonstration normal...
Abstract Know your bacteria! Two fluorene‐based, conjugated polymers with oligo(ethylene glycol)‐ and poly(ethylene glycol)‐tethered spacers have been prepared by the Suzuki coupling polymerization reactions. β‐Glucose α‐mannose residues were covalently attached to post‐polymerization functionalization thiol‐functionalized carbohydrates under basic conditions. Investigations on their use as biosensing materials for detection of Escherichia coli are reported (see figure). magnified image...
An outbreak of influenza A(H1N1)v was confirmed in May and June 2009 a boarding school South East England involving 102 symptomatic cases with influenza-like illness. Influenza infection laboratory-confirmed by PCR 62 pupils one member staff. Control measures were implemented as soon case included closure, active finding treatment well post-exposure prophylaxis offered to the entire population. Had had been detected earlier, closed earlier commenced after initial detected, we may have seen...
Policy makers have introduced a number of measures to encourage older workers stay in the labour market, with improving access training particular priority. action appeared justified by evidence that are less likely participate training, and more never been offered employers – key finding Taylor Urwin’s (2001) review Labour Force Survey (LFS) data from 1997. This article models LFS 2007 assess whether age remained predictor inequalities training. It finds men over 50 among those least...
Summary The goal of this study is to apply an ontology based assessment process electronic health record (EHR) data and determine its usefulness in characterizing quality for calculating example eMeasure (CMS178). uses a that references separate quality, domain task ontologies compute measures on proportions constraints are satisfied. These quantities indicate how well the conforms it fits task. was performed de-identified 200,000 encounter sample from hospital EHR. CodingConsistency poor...
OBJECTIVE The purpose of the study is to evaluate relationship between HbA1c and severity coronavirus disease 2019 (COVID-19) outcomes in patients with type 2 diabetes (T2D) acute COVID-19 infection. RESEARCH DESIGN AND METHODS We conducted a retrospective using observational data from National COVID Cohort Collaborative (N3C), longitudinal, multicenter U.S. cohort Patients were ≥18 years old T2D confirmed infection by laboratory testing or diagnosis code. primary outcome was 30-day...
Abstract Background Metformin has decreased SARS-CoV-2 RNA in 4 cell lines. In a RCT of &gt; 1,000 majority vaccinated outpatients, COVID-19 related ED visits/Hospitalization/Death occurred 4.7% the metformin vs 9.0% placebo group by Day 28; clinician-diagnosed Long Covid (LC) 6.2% 10.3% 300; and 14% 23% had detectable nasal viral load on 10. trial 20 adults, 60% 100% 4. Observational analyses report associations between prevalent less severe acute COVID. Given these data, we assessed...
Accrual success is one key determining factor for the of clinical trials. Global data analyses all terminated trials reported that 55% were due to low accrual rates. Failure meet goals have a significant impact on costs sponsors, academic institutions, investigators, and society at large. The ability predict trial with high precision before starts would be highly valuable, preventing allocation critical resources unlikely goals. In present study, we constructed dataset predicting failure...
Purpose The purpose of this article is to discuss methods for leading and managing inclusive entrepreneurial ecosystems (IEEs) that encourage inclusion participation from underrepresented portions their community entrepreneurship represent help all types entrepreneurs in region. Design/methodology/approach This uses an in-depth interview method data collection. Findings Our findings present challenges opportunities striving have more by empathizing with different populations co-creating new...
Objectives/Goals: Our study team won a Public Health Answers to Speed Tractable Results (PHASTR) contract conduct target trial emulation answer “Does metformin show reduction of severe outcomes COVID-19 or Long COVID in the N3C Data Enclave?” We quickly delivered an due productive technical and collaboration support N3C. Methods/Study Population: analytic plan was updated based on helpful feedback from PHASTR program. performed analysis using data, comparing adult new users controls...
abstract The concepts of core, generic or key skills are now ubiquitous in educational discourse and an integral part recommendations for education training programmes from school to university. It is our contention that ‐‐ the sense free‐standing, context‐independent abilities such without philosophical empirical support entirely illusory. Although ideas integrated core units common learning experiences underpinning post‐school curriculum have some justification, pursuit general...
Research evidence suggests that SMEs are significantly less likely than larger employers to provide or fund formal training leading qualifications for employees. The (or more accurately learning) does take place in most tends be informal, on‐the‐job and related short‐term business objectives problems. There strong arguments suggest this type of approach is perfectly rational from the point view small business, but may not produce optimum level mix skills economy as a whole. Moreover, there...