A5028309567- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Sleep and Wakefulness Research
- Gastrointestinal motility and disorders
- Neuroscience and Music Perception
- Neurobiology of Language and Bilingualism
- Advanced MRI Techniques and Applications
- Dementia and Cognitive Impairment Research
- Olfactory and Sensory Function Studies
- Motor Control and Adaptation
- Music Therapy and Health
- Neuroscience and Neuropharmacology Research
- Biochemical Analysis and Sensing Techniques
- Advanced Chemical Sensor Technologies
- Biomedical and Engineering Education
- Estrogen and related hormone effects
- Menopause: Health Impacts and Treatments
- Frailty in Older Adults
- Health, Environment, Cognitive Aging
- Eating Disorders and Behaviors
- Action Observation and Synchronization
- Cancer-related cognitive impairment studies
Linköping University
2015-2024
Western University
2019-2024
Institut des Sciences Cognitives Marc Jeannerod
2021
Hartford Hospital
2010-2015
Hartford Financial Services (United States)
2010-2015
Yale University
2013
University of Wisconsin–Madison
2006-2009
Mayo Clinic in Arizona
2003
Increased perception of visceral stimuli is a key feature Irritable Bowel Syndrome (IBS). While altered resting-state functional connectivity (rsFC) has been also reported in IBS, the relationship between hypersensitivity and aberrant rsFC unknown. We therefore assessed within salience, sensorimotor default mode networks patients with without healthy controls (HCs). An exploratory magnetic resonance imaging study was performed 41 women IBS 20 HCs. Group independent component analysis used to...
Narcolepsy is a chronic sleep disorder caused by loss of hypocretin-1 producing neurons in the hypothalamus. Previous neuroimaging studies have investigated brain function narcolepsy during rest using positron emission tomography (PET) and single photon computed (SPECT). In addition to hypothalamic thalamic dysfunction they showed aberrant prefrontal perfusion glucose metabolism narcolepsy. Given these findings structure narcolepsy, we anticipated that changes functional magnetic resonance...
Changes in brain-gut interactions have been implicated the pathophysiology of chronic visceral pain irritable bowel syndrome (IBS). Different mechanisms sensitization afferent pathways may contribute to reports and associated brain changes that characterize IBS. They include increased gut permeability immune system activation, an imbalance descending inhibitory facilitatory mechanisms. In order study involvement these mechanisms, correlations between epithelial live bacterial passage,...
Olfactory dysfunction is an early manifestation of Parkinson's disease (PD). The present study aimed to illustrate potential differences between PD patients and healthy controls in terms neural activity functional connectivity within the olfactory brain network. Twenty twenty were examined with fMRI resting-state fMRI. Data analysis included data-driven tensorial independent component (ICA) task-driven general linear model (GLM) analyses. probabilistic ICA based on temporal concatenation...
The study investigated brain activity changes during performance of a verbal working memory task in population adolescents with narcolepsy. Seventeen narcolepsy patients and twenty healthy controls performed simultaneous fMRI EEG acquisition. All subjects also underwent MRS to measure GABA Glutamate concentrations the medial prefrontal cortex. Activation levels default mode network left middle frontal gyrus were examined investigate whether is characterized by an imbalance cognitive...
Abstract Irritable bowel syndrome (IBS) is a visceral pain condition with psychological comorbidity. Brain imaging studies in IBS demonstrate altered function anterior insula (aINS), key hub for integration of interoceptive, affective, and cognitive processes. However, alterations aINS excitatory inhibitory neurotransmission as putative biochemical underpinnings these functional changes remain elusive. Using quantitative magnetic resonance spectroscopy, we compared women healthy (healthy...
Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on activation pattern 4 olfactory brain regions: anterior posterior piriform cortex, orbitofrontal insula. Twenty-two healthy participants normal were examined fMRI, 2 lengths (6 s 15 s) TRs (0.901 1.34 s). Data analyzed using General Linear Model (GLM), Tensorial Independent Component Analysis...
Women with early bilateral salpingo-oophorectomy (BSO) have greater Alzheimer's disease (AD) risk than women spontaneous menopause (SM), but the pathway toward this is understudied. Considering associative memory deficits may reflect signs of AD, we studied how BSO affected brain activity underlying memory.
Abstract Altered neural mechanisms are well-acknowledged in irritable bowel syndrome (IBS), a disorder of brain-gut-communication highly comorbid with anxiety and depression. As key hub corticolimbic inhibition, medial prefrontal cortex (mPFC) may be involved disturbed emotion regulation IBS. However, aberrant mPFC excitatory inhibitory neurotransmission potentially contributing to psychological symptoms IBS remains unknown. Using quantitative magnetic resonance spectroscopy (qMRS), we...
There is growing evidence as to the benefits of collecting BOLD fMRI data with increased sampling rates. However, many newly developed acquisition techniques collect ultra-short TRs require hardware, software, and non-standard analytic pipelines that may not be accessible all researchers. We propose incorporate method shifted echo into a standard multi-slice, gradient EPI sequence achieve higher rate TR less than one second acceptable spatial resolution. further temporal averaging...
Abstract The current state of label conventions used to describe brain networks related executive functions is highly inconsistent, leading confusion among researchers regarding network labels. Visually similar are referred by different labels, yet these same labels distinguish within studies. We performed a literature review fMRI studies and identified nine frequently-used that topographically or functionally neural networks: central (CEN), cognitive control (CCN), dorsal attention (DAN),...