- Transplantation: Methods and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Organ Transplantation Techniques and Outcomes
- Mycobacterium research and diagnosis
- Polyomavirus and related diseases
- Cytomegalovirus and herpesvirus research
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Family and Patient Care in Intensive Care Units
- Viral Infections and Immunology Research
- Mechanical Circulatory Support Devices
- Pancreatitis Pathology and Treatment
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Eosinophilic Disorders and Syndromes
- Renal Transplantation Outcomes and Treatments
- Food Allergy and Anaphylaxis Research
- Respiratory viral infections research
- Breast Lesions and Carcinomas
- Organ and Tissue Transplantation Research
- Pulmonary Hypertension Research and Treatments
- Occupational and environmental lung diseases
- Hemophilia Treatment and Research
Northwestern University
2024
INTEGRIS Baptist Medical Center
2016-2020
Saint Thomas Midtown Hospital
2019
Baptist Hospital
2019
Henry Ford Hospital
2003-2013
Henry Ford Health System
2008-2013
University of North Carolina at Chapel Hill
2002
Current treatments for idiopathic pulmonary fibrosis slow the rate of lung function decline, but may be associated with adverse events that affect medication adherence. In phase 2 trials, pamrevlumab (a fully human monoclonal antibody binds to and inhibits connective tissue growth factor activity) attenuated progression without substantial events.
Idiopathic pulmonary fibrosis (IPF) is a rare and progressive disease that causes cough, exertional dyspnea, impaired quality of life, death.
Cytomegalovirus (CMV) is a driver of negative outcomes after lung transplant (LTX) and primary prophylaxis (PPX) with valganciclovir (VGC) standard-of-care. VGC associated myelosuppression, prompting interest in letermovir (LTV).
The case report is presented of a patient with West Nile virus infection and ventilator dependent respiratory failure in whom bilateral diaphragmatic paralysis developed. If the prevalence continues to rise, recognition related complications will become increasingly important pulmonary/critical care physician.
Cytomegalovirus (CMV) is associated with detrimental outcomes after lung transplantation (LTX); primary prophylaxis (PPX) valganciclovir (VGC) guideline-recommended. VGC myelosuppression, spurring interest in letermovir (LTV).
Abstract Background Lung transplantation is the only life-saving therapy for end-stage lung disease. However, has worst survival among all solid organ transplants. 1 We applied machine learning to a large standardized electronic health record (EHR) dataset from United Network Organ Sharing (UNOS) test whether pre- transplant and peri-transplant donor recipient features can predict one-, three- five-year survival, or favorable long-term outcomes in transplant. Methods used data 43,869 first...