A5089437734- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Neuroendocrine regulation and behavior
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Neuropeptides and Animal Physiology
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Neural dynamics and brain function
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Motor Control and Adaptation
- Schizophrenia research and treatment
- Attention Deficit Hyperactivity Disorder
- EEG and Brain-Computer Interfaces
- Neuroscience and Music Perception
- Tryptophan and brain disorders
- Zebrafish Biomedical Research Applications
- Nerve injury and regeneration
- Autism Spectrum Disorder Research
- Olfactory and Sensory Function Studies
- Ion channel regulation and function
CEA Paris-Saclay
2022-2024
Institut de Recherche sur les Lois Fondamentales de l'Univers
2022-2024
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2022-2024
Université Paris-Saclay
2022
Radboud University Nijmegen
2003-2016
Radboud University Medical Center
2005-2016
Maastricht University Medical Centre
2000-2001
Leiden University
1996-2001
Dr Kolbach Kliniek
2001
KU Leuven
2000
Eighteen patients suffering from Parkinson9s disease and nineteen control subjects, who were matched for age intelligence, compared in tests measuring "shifting aptitude" at cognitive motor levels (word production, sorting blocks or animals, finger pushing sequences). It was found that Parkinson produced fewer different names of animals professions one minute than needed more trials detecting a shift criterion, responses change sequence subjects. These results are interpreted as reflecting...
Developing animal models for psychiatric disorders is a complicated process. This principally due to our relatively limited knowledge of the processes underlying such illnesses as depression and schizophrenia. Unfortunately this can lead vicious circle. Our disease leads inability develop proper models, which will an increase about neuronal mechanisms illness. In present review we have tried show that with respect schizophrenia situation slowly changing. Using electrophysiological...
Social cognition is an endophenotype that impaired in schizophrenia and several other (comorbid) psychiatric disorders. One of the modulators social dopamine, but its role not clear. The effects dopamine are mediated through receptors, including D1 receptor (Drd1). Because current Drd1 agonists selective, pharmacological tools sufficient to delineate Drd1. Here, we describe a novel rat model with genetic mutation which measured basic behavioural phenotypes cognition. I116S was predicted...
Abstract Indirect evidence suggests that patients with Parkinson's disease (PD) have deficits not only in motor performance, but also the processing of sensory information. We investigated role information PD a broad range severities and group age‐matched controls. Subjects were tested two conditions: pointing to remembered visual target complete darkness (DARK) presence an illuminated frame light attached index finger (FRAME). Differences errors these conditions reflect effect feedback on...
SummaryInvestigations of the effects advance information on movement preparation in Parkinson's disease using reaction time (RT) measures have yielded contradictory results. In order to obtain direct regarding course preparation, we combined RT measurements a precueing task with multi-channel recordings movement-related potentials present study. Movements index and middle fingers left right hand were either precued or not by side (left hand) required response. Reaction times slower for...
The ability to share time and shift attention between bimanual simultaneous motor tasks were studied in 18 patients with Parkinson9s disease (PD) 19 age- intelligence-matched controls. task consisted of drawing triangles the dominant hand squeezing a rubber bulb nondominant hand. Motor performance was measured using variables: amplitude squeezing, frequency velocity triangles. After eliminating variance due baseline differences single-handed performance, PD controls turned out be similar...